Mike Dorrity

Collectivity in living systems: emergence, function, and evolution

Please join us for this exciting new conference on the emergence, function and evolution of biological collectives - unpacking the wonderful world of self-organization: www.embl.org/about/info/c...

Group Leader – AI in Biology Are you ready to lead groundbreaking research in AI for Biology? Join us at EMBL! We are seeking a visionary scientist to establish their own independent research group bridging innovations in machine...

Are you an AI expert who wants to stay in academia and change the world by understanding the most complex things we know - living organisms? Want to lead your own group, based in Heidelberg DE, working language English? @embl.org is hiring in AI embl.wd103.myworkdayjobs.com/en-US/EMBL/j...

Right back at you Greg !

An Elmo variant I haven’t seen yet - thanks !

Very excited to share - the ERC StG is a game-changer for us 🙏 We're going to learn the rules for timing control across cell types in the embryo and we think we can tune them too 🎛️ ⏳📈- reach out if you’d like to be involved !

Don’t know what I was expecting, ha. But my world was a lot smaller before I found a home here !

EMBL is an amazing place to start a lab and bring new direction to your research program (ask me how I know) - come join us in Heidelberg !

Group Leader - Genome Biology Unit Are you ready to lead groundbreaking research in Genome Biology? Join us at EMBL! We are seeking a motivated scientist to lead an independent research group addressing exciting and original biological...

To all post-docs: The Genome Biology dept ‪@embl.org
has an Independent faculty position. Fantastic place to set up your lab –great package: core funding, fantastic Ph.D. students, cutting edge core facilities & great colleagues. Closing date Sept 19th
embl.wd103.myworkdayjobs.com/en-US/EMBL/j...

Group Leader – Molecular Systems Biology Unit Are you ready to lead groundbreaking research in Molecular Systems Biology? Join us at EMBL! We are seeking a motivated scientist to lead an independent research group, addressing original biological ...

Ready to lead pioneering research that bridges systems-level investigations of biological systems to molecular mechanism? The EMBL Molecular Systems Biology Unit in Heidelberg is hiring a Group Leader!

🔔 Proud to share the preprint of my PhD work in the Petridou group @nicolettapetridou.bsky.social @embl.org ✨

“A closed feedback between tissue phase transitions and morphogen gradients drives patterning dynamics” 🐟 🔁 📶

🔗 www.biorxiv.org/content/10.1...

#devbio #biophysics

🧵⤵️

Discovery and characterisation of gene by environment and epistatic genetic effects in a vertebrate model Phenotypic variation arises from the interplay between genetic and environmental factors. However, disentangling these interactions for complex traits remains challenging in observational cohorts such...

We have updated our preprint on GxE and epipstatic interactions in vertebrates, lead authors Bettina Welz and @saulpierotti.bsky.social, a collaboration between my lab, @wittbrodtlab.bsky.social, Felix Loosli and Kiyoshi Naruse's lab. www.biorxiv.org/content/10.1...

I attended the exciting symposium organized by @floravincent.bsky.social @mwdorr.bsky.social, @nicoledubilier.bsky.social, @gautamdey.bsky.social & Susanna Coelho

LOTs of takeaways from the Symposium (from biology to climate change)

🚨Here are a few important ones in my listicle below 👇

Teeth first evolved as sensory tissue in the armored exoskeletons of ancient fish, fossil scans find Anyone who has ever squirmed through a dental cleaning can tell you how sensitive teeth can be. This sensitivity gives important feedback about temperature, pressure—and yes, pain—as we bite and chew ...

New paper from the lab: Our teeth arose as sensory organs on the outside of the body of ancient jawless fish.!! Congrats to Yara Haridy and the team!
Background and video: phys.org/news/2025-05...
Open Access Paper: www.nature.com/articles/s41...
News and Views: www.nature.com/articles/d41...

Thanks for all the great discussions - @msarscentre.bsky.social is a one-of-kind research environment ! and very sunny in my limited sampling..

A man faces an audience in a seminar room, speaking. On a screen behind him, a slide with an image of a fish embryo, and the caption "you could just record developing embryos..."

How does temperature impact development? 🌡️ Michael Dorrity @mwdorr.bsky.social from @embl.org shared his integrated approach to revealing the relationship between temperature stress and developmental rate in fishes 🐟🐠 Thank you for a great talk and discussions! 👏

Junior / Assistant Specialist: Kim Lab, Developmental & Cell Biology University of California, Irvine is hiring. Apply now!

I am hiring for a research technician role in my new lab at UC Irvine studying how transcription factors control cell identity. If you know any graduating undergrads or postbacs looking for a position, please spread the word! Apply by May 9 for full consideration. recruit.ap.uci.edu/JPF09594

Postdoctoral Researcher- Brady Lab University of California, Davis is hiring. Apply now!

We have a postdoc position that just opened up in the Brady lab on reprogramming tomato root system architecture in response to changes in nutrient availability - please consider applying! recruit.ucdavis.edu/JPF07095

Developmental timing across species: From mechanisms to evolutionary insights Like choreography, development consists of a highly ordered suite of steps and transitions. Modifying developmental tempo can affect final size and composition of tissues, as well as their plasticity…

EMBOMtg Paris May 6-9
@aydoganlab.bsky.social @jamesbriscoe.bsky.social @brunetlab.bsky.social @ebisuyamiki.bsky.social @mwdorr.bsky.social @beyerlab.bsky.social @franckp.bsky.social @janereznick.bsky.social @olmedo-lab.bsky.social @perez-carrasco.bsky.social
meetings.embo.org/event/25-dev...

Group Leader - Molecular Mechanisms of Environmental Adaptation We are seeking to recruit a highly motivated scientist to establish and lead an independent research laboratory at the EMBL Epigenetics and Neurobiology Unit in Rome. EMBL provides a unique environmen...

Want to start an independent research group? ...with core funding, outstanding facilities & a curiosity-driven culture? Join us at @embl.org

We are recruiting across research themes, inc (epi)genomics, human dev bio, predictive modelling & neurobiology👇

embl.wd103.myworkdayjobs.com/en-US/EMBL/d...

Wild frontiers of model organisms

Still time to submit an Abstract for the @embl.org symposium on the Wild Frontiers of Model Systems !
If you’re into unconventional, non model systems, bringing more ecology in our understanding of biological processes, Lab-field interface this is for you.
www.embl.org/about/info/c...
#protistsonsky

artwork by Sayeh Gorjifard (@lampoona.bsky.social)

📢Job alert! #joboffer #plantscijobs
Are you interested in plant gene regulation and synthetic biology? I have two open #postdoc positions in my #EmmyNoether group @hhu.bsky.social. See below for more information (or visit www.synthetic-biology.hhu.de/available-po...).

Please share!

Xmas teaser: Mike Dorrity @mwdorr.bsky.social and I are looking for a joint postdoc to study "The Hallmarks of Thermal Adaptation" in Aquatic Chordates as part of the EIPOD-LinC program www.embl.org/about/info/p... and the partnership between @embl.org and @msarscentre.bsky.social.

Fish friends and beyond - I’m co-organizing a conference and it’d be great to see you there. Check it out!

Behind in posting, but thinking back to sunnier months…we had a great scientific retreat on theory in biology, trajectories, timing and environmentally-sensitive growth with our friends in the Vu lab and S. Werner. Thanks to Soham for the excellent photo!

Wild frontiers of model organisms

Join us for a brand new EMBO/EML Symposium on 'Wild frontiers of model organisms' in April 2025 ❗
Bottom line:
- great line up of speakers: M. McFall-Ngai, Jb Raina, M. Prakash, E Santos etc...
- to explore old models but in new context or ways of building new model systems
s.embl.org/ees25-02 1/n

Graphical abstract of the study

Out now in Dev Cell! scRNAseq trajectories describe the cascade of gene expression as cells differentiate, but turning them into a clear understanding of the underlying biology of a cell type's development remains challenging. authors.elsevier.com/c/1k9qj5Sx5g... (1/)

+1 here if you don’t mind

My lab is looking for a postdoc shared with @OliverStegle (incoming). Join us to design ambitious multi-sample single-cell experiments in developing embryos, model temporal response patterns, test predictions.

Open to different backgrounds and expertise. If you’re interested, get in touch soon!

I’m the worst tweeter I know - link to our now published study above. Thanks to fantastic co-authors + Cole and David as well!

Very thankful to the anonymous reviewers, whose input added new dimensions to our study:
- new sci-rna-seq experiments for 🥶 and atf6 mutants
- upr mutant fails to accelerate development at high temperature 🤯
- explicit DE testing of temperature (not stage) responsive genes