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Alan McNally

@alanmcn1.bsky.social

Head of the School of Infection, Inflammation & Immunology @ Uni Birmingham. Proud Scot. Oversaw a few Covid PCR tests

6,435 Followers  |  583 Following  |  1,675 Posts  |  Joined: 03.09.2023  |  2.1659

Latest posts by alanmcn1.bsky.social on Bluesky

And in the process destroying UK HE

07.10.2025 21:16 β€” πŸ‘ 2    πŸ” 1    πŸ’¬ 1    πŸ“Œ 0
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I sang Jerusalem with Robert Jenrick at school β€” he’s wrong about race The Conservative MP has complained that, visiting Handsworth in Birmingham, he didn’t see β€˜another white face’. You can’t judge whether someone is integrated by skin colour, argues fellow Wulfrunian S...

I've responded to Robert Jenrick's vile comments in @thetimes.com

www.thetimes.com/life-style/c...

07.10.2025 14:27 β€” πŸ‘ 392    πŸ” 103    πŸ’¬ 23    πŸ“Œ 10
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Beautiful juxtaposition on BBC news website here

07.10.2025 19:27 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
<i>Microbial Genomics </i> Deputy Editor-in-Chief: Call for Expressions of interest

After being with the journal since its very inception, the time has come for me to step back from Microbial Genomics. This is a wonderful opportunity to have a leadership role in one of the leading journals for microbial genomics research

microbiologysociety.org/news/society...

07.10.2025 08:43 β€” πŸ‘ 22    πŸ” 24    πŸ’¬ 1    πŸ“Œ 1
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Whole-genome sequencing reveals Enterobacter hormaechei as a key bloodstream pathogen in six tertiary care hospitals in southwestern Nigeria Enterobacter spp. are an important cause of healthcare-associated bloodstream infections that are uncommonly reported in Africa. This study utilized whole-genome sequencing to characterize Enterobacte...

Thanks also to
πŸ‡³πŸ‡¬CDC & #AMRsurveillance system, without which we'd not've seen this;
GHRU-GSA consortium & @nihr.bsky.social
for enabling πŸ‡³πŸ‡¬ to institute genomic surveillance of AMR. Read our #OpenAccess MGen
@microbiologysociety.org
paper & let's know what you think doi.org/10.1099/mgen... END

06.10.2025 20:23 β€” πŸ‘ 1    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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Unbelievable, Bakta reached its 1,000th citation!

A huge shout out and thank you to all Bakta users, bug reporters, those sharing ideas and suggesting features...

...just the entire incredibly supporting binfie community!

Without you, Bakta wouldn't be the same.

Thank you!

06.10.2025 08:11 β€” πŸ‘ 45    πŸ” 10    πŸ’¬ 1    πŸ“Œ 0
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Varicella-zoster virus reactivation and the risk of dementia - Nature Medicine Large-scale longitudinal health records reveal consistent association of varicella-zoster virus reactivation with dementia.

A new Nature Medicine study analyzing health records from >100 million people in the US offers compelling evidence that reactivation of varicella-zoster virus (VZV) ,the same virus that causes chickenpox and shingles may contribute to dementia risk.
www.nature.com/articles/s41...

06.10.2025 16:46 β€” πŸ‘ 217    πŸ” 83    πŸ’¬ 8    πŸ“Œ 8
Post image 06.10.2025 14:14 β€” πŸ‘ 90    πŸ” 16    πŸ’¬ 7    πŸ“Œ 1
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Scientists win Nobel Prize for groundbreaking immune system work The prize-winning discovery explains how the immune system attacks hostile infections, but not the body's own cells.

T-Regs win the Nobel prize.

And our School's very own Profs Ye Oo and Graham Anderson were just awarded a Wellcome Discovery grant with Prof Sakaguchi as a Co-I on their project.........

www.bbc.co.uk/news/article...

06.10.2025 13:07 β€” πŸ‘ 6    πŸ” 2    πŸ’¬ 1    πŸ“Œ 0
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Resistance mutation supply modulates the benefit of CRISPR immunity against virulent phages Only a fraction of bacterial genomes encode CRISPR-Cas systems but the selective causes of this variation are unexplained. How naturally virulent bacteriophages (phages) select for CRISPR immunity has...

New preprint!

Ever wondered why only a fraction of genomes encode CRISPR immunity? 🧬 🦠

Turns out CRISPR is rarely beneficial against virulent phages, being most beneficial against those for which resistance mutations are rare!

An epic effort by Rosanna Wright

www.biorxiv.org/content/10.1...

06.10.2025 06:27 β€” πŸ‘ 89    πŸ” 46    πŸ’¬ 3    πŸ“Œ 1

Never thought I'd say this. It's
gonna be harsh and might
give you angry feelings when
you see it. I've come
up with one simple life rule:
Never ever (I know you're
gonna, but please don't)
let yourself feel stupid when
you look at the first words
down the left side of this post

05.10.2025 20:18 β€” πŸ‘ 193    πŸ” 42    πŸ’¬ 12    πŸ“Œ 3

Some seriously bad officiating at the nfl this weekend.

05.10.2025 20:32 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
I RECENTLY bought a new
laptop which, to my surprise,
was made by HP. This must be
a really progressive company to
diversify from producing baked
beans, soup and tomato sauce
to making computers. Their
competitors should take a leaf out
of HP's book and get busy. Maybe
we could see new gadgets like a
Fray Bentos Fitbit, Batchelors
Bluetooth Earbuds or even a Mr
Kipling Raspberry Smartphone.
Heinz Doofenshmirtz, email

I RECENTLY bought a new laptop which, to my surprise, was made by HP. This must be a really progressive company to diversify from producing baked beans, soup and tomato sauce to making computers. Their competitors should take a leaf out of HP's book and get busy. Maybe we could see new gadgets like a Fray Bentos Fitbit, Batchelors Bluetooth Earbuds or even a Mr Kipling Raspberry Smartphone. Heinz Doofenshmirtz, email

subscriptions >>> shop.viz.co.uk/viz349bs

05.10.2025 18:55 β€” πŸ‘ 246    πŸ” 48    πŸ’¬ 4    πŸ“Œ 1
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Monoclonal antibodies protect against pandrug-resistant Klebsiella pneumoniae - Nature Capsule-specific human monoclonal antibodies are protective against bloodstreamΒ infection by Klebsiella pneumoniae sequence type 147 in a mouse model of septicaemia, and could provide a useful strategy against pathogens with antimicrobial resistance.

Nature research paper: Monoclonal antibodies protect against pandrug-resistant Klebsiella pneumoniae

go.nature.com/4gXwTtu

05.10.2025 09:29 β€” πŸ‘ 28    πŸ” 7    πŸ’¬ 0    πŸ“Œ 1

Harry Kane has scored 18 goals this season.

It’s the first week of October!!!!!

04.10.2025 17:41 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Sign that reads "Major Gas Restaurant"

Sign that reads "Major Gas Restaurant"

Truth in advertising ... or poorly designed sign?

03.10.2025 18:32 β€” πŸ‘ 7    πŸ” 1    πŸ’¬ 1    πŸ“Œ 0

One of the biggest losses in the UK has been our newspaper industry. Once the envy of the world, even when Murdoch owned most of it, now 95% is little more than dirt cheap, right-wing ragebait. Hard to believe that The Times was once called "The Thunderer".

03.10.2025 16:55 β€” πŸ‘ 182    πŸ” 15    πŸ’¬ 11    πŸ“Œ 0
Lecturer in Microbiology, Permanent, 1 FTE, Contract Type B, 011296 | University Vacancies Ireland

Lecturership in Microbiolgy @uniofgalway.bsky.social. Application submission deadline coming soon - October 9th. universityvacancies.com/university-g...

03.10.2025 13:38 β€” πŸ‘ 1    πŸ” 8    πŸ’¬ 0    πŸ“Œ 0

Lancet editor: "I can’t forgive Bhattacharya and Makary...both know reliable evidence does not exist to restrict paracetamol use during pregnancy...both know evidence linking vaccines to autism simply doesn't exist. What are they doing?"

[politics - that's what]

www.thelancet.com/action/showP...

03.10.2025 15:30 β€” πŸ‘ 25    πŸ” 15    πŸ’¬ 1    πŸ“Œ 1
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BBC Political Editor Chris Mason stuck up Nigel Farage’s arse Chris Mason, the BBC’s political editor, is stuck up Nigel Farage’s arse and there appears to be little prospect of an imminent extraction.

NEWS! BBC Political Editor Chris Mason stuck up Nigel Farage’s arse newsthump.com/2025/10/03/b...

03.10.2025 10:28 β€” πŸ‘ 46    πŸ” 15    πŸ’¬ 2    πŸ“Œ 2

The centre of the pizza should be devoid of toppings. Any juicy morsels there get chopped into tiny slivers and are lost

02.10.2025 19:55 β€” πŸ‘ 45    πŸ” 3    πŸ’¬ 8    πŸ“Œ 2
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Clostridioides difficile pathogenesis and control Nature Reviews Microbiology, Published online: 02 October 2025; doi:10.1038/s41579-025-01242-2Clostridioides difficile infection is challenging to diagnose and treat and is associated with considerable mortality, morbidity and economic costs worldwide. In this Review, Chilton et al. discuss changes in global epidemiology, breakthroughs in pathogenesis and antibiotic resistance, the role of microbiota dysbiosis and the potential for microbiota-based therapeutics for Clostridioides difficile infection.

New online! Clostridioides difficile pathogenesis and control

02.10.2025 13:06 β€” πŸ‘ 4    πŸ” 3    πŸ’¬ 0    πŸ“Œ 1
A printed poem which reads:

I hav for breakfast Weetabix

I hav for lunch some meat

I have for tea 2 sosajis and thats enuf to eat

Peter Hazel, 5

A printed poem which reads: I hav for breakfast Weetabix I hav for lunch some meat I have for tea 2 sosajis and thats enuf to eat Peter Hazel, 5

On National Poetry Day, the greatest poem I have ever read

02.10.2025 08:41 β€” πŸ‘ 3558    πŸ” 939    πŸ’¬ 61    πŸ“Œ 72
Sgùrr na Strì, the 'peak of strife' #IsleofSkye #Scotland #Highlands www.damianshields.com

Sgùrr na Strì, the 'peak of strife' #IsleofSkye #Scotland #Highlands www.damianshields.com

Sgùrr na Strì, the 'peak of strife' #IsleofSkye #Scotland #Highlands www.damianshields.com

02.10.2025 09:16 β€” πŸ‘ 160    πŸ” 12    πŸ’¬ 2    πŸ“Œ 0
From r/chatGPTpro, 25 minutes ago: chatGPT blocked at work

Today my job decided to block the site. I use chatGPT to create SOPs (standard operating practices) and power points and polish my emails. What should I do now four question marks. It has 0 upvotes and 20 comments

From r/chatGPTpro, 25 minutes ago: chatGPT blocked at work Today my job decided to block the site. I use chatGPT to create SOPs (standard operating practices) and power points and polish my emails. What should I do now four question marks. It has 0 upvotes and 20 comments

help my job says i have to do my job what do i do help

31.07.2025 22:36 β€” πŸ‘ 8930    πŸ” 2077    πŸ’¬ 54    πŸ“Œ 312

I am told by a more than good friend I would trust with my life that the Uk contribution to those stats is β€œMass shootings are firearm-related violence with at least four casualties”

01.10.2025 20:29 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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PSG V Barcelona tonight. Remembering two former greats: David Ginola (PSG) and Ronald Koeman (Barcelona).

01.10.2025 17:04 β€” πŸ‘ 44    πŸ” 8    πŸ’¬ 1    πŸ“Œ 1

Cos it’s easy to.

Kleb and Acinetobacter do this for fun.

01.10.2025 17:03 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

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