The Powrie Lab's Avatar

The Powrie Lab

@powrielab.bsky.social

Powrie Lab news and Mucosal Immunology content! Based at the Kennedy Institute of Rheumatology @kiroxford.bsky.social Posts are by members of the Powrie Lab, not necessarily representative of the lab as a whole.

897 Followers  |  1,403 Following  |  41 Posts  |  Joined: 27.03.2025  |  1.5852

Latest posts by powrielab.bsky.social on Bluesky


Post image Post image

Weโ€™re really pleased to share that our excellent DPhil student, Amit, successfully defended his PhD thesis last week! We had a great time celebrating with you and look forward to seeing what your next chapter holds!๐ŸŽ‰๐Ÿง‘โ€๐Ÿ’ป๐Ÿฅ‚

@kiroxford.bsky.social
@amit-halkhoree.bsky.social @nickilott.bsky.social

18.02.2026 20:18 โ€” ๐Ÿ‘ 18    ๐Ÿ” 6    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
Client Challenge

โ˜•Borsa et al. show that asymmetric #Tcell division after activation requires #autophagy to promote #mitochondria turnover, with T cells inheriting older mitochondria showing decreased degradation, reduced memory potential and altered metabolism.
bit.ly/458ODgL

13.01.2026 17:59 โ€” ๐Ÿ‘ 12    ๐Ÿ” 5    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
Post image

Celebrating #February11 by highlighting Professor Claudia Mauri, the Editorโ€‘inโ€‘Chief of @ceijournal.bsky.social Her leadership and expertise continue to shape the future of immunology.

Read the interview on the BSI website here: https://bit.ly/4abuedR

#WomenInScience

11.02.2026 13:48 โ€” ๐Ÿ‘ 11    ๐Ÿ” 3    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Post image

This #February11 we are celebrating Prof Jessica Teeling, winner of the BSI Public Engagement Award! Her grantโ€‘supported โ€œSnakes and Letters for a Healthy Brainโ€ project is inspiring conversations on dementia risk + immunity. #WomenInScience

Read here: https://bit.ly/3Ktiito

11.02.2026 11:15 โ€” ๐Ÿ‘ 7    ๐Ÿ” 3    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Post image

Marking #February11 by celebrating Professor Tracy Hussell, BSI President, and her Nature Mentoring Award for Lifetime Achievement.

A great recognition of her commitment to supporting early career researchers and strengthening the immunology community.

#WomenInScience #Immunology

11.02.2026 16:14 โ€” ๐Ÿ‘ 12    ๐Ÿ” 5    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Post image

Congratulations to the wonderful Natasha for successfully defending her DPhil thesis! Weโ€™re excited to see what comes next for Natasha and her MAIT cell story whilst she continues her project as a postdoctoral researcher๐Ÿฅณ๐Ÿ‘ฉโ€๐Ÿ”ฌ

@kiroxford.bsky.social

11.02.2026 20:44 โ€” ๐Ÿ‘ 32    ๐Ÿ” 6    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
Preview
Contextualizing TH17 cells in cancer - Nature Reviews Immunology T helper 17 (TH17) cells can have both pro-tumour and antitumour effects. Understanding how they are regulated by environmental and regulatory cues according to context will inform strategies to harne...

New year, new paper! Thrilled to share that our review โ€œContextualising TH17 cells in cancerโ€ is out now!

Congratulations to Declan & team for a fantastic, in depth overview๐Ÿฅณ

Go give it a read here:
doi.org/10.1038/s415...

@natrevimmunol.nature.com
@kiroxford.bsky.social

07.01.2026 10:53 โ€” ๐Ÿ‘ 28    ๐Ÿ” 12    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Post image Post image Post image Post image

Last night was our Lab Christmas party! Special thanks to Claire and Nick for organising some excellent party games for us (guessing the flavour of Skittles whilst blindfolded is much harder than youโ€™d think!) and to Branca for hosting us๐ŸŽ…๐ŸŽ„๐ŸŒŸ

@kiroxford.bsky.social
@nickilott.bsky.social

12.12.2025 21:09 โ€” ๐Ÿ‘ 13    ๐Ÿ” 5    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

An excellent opportunity, please have a look at the position below!๐Ÿงซ๐Ÿ‘ฉโ€๐Ÿ”ฌ

11.12.2025 11:27 โ€” ๐Ÿ‘ 8    ๐Ÿ” 5    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Job Details

Weโ€™re hiring! Two postdoctoral research positions are available in our lab - one in mucosal immunology, and one in exposome immunology (MRC CoRE)! Apply by December 22nd!๐ŸŽ„

Position 1: tinyurl.com/2mh44tn4
Position 2: tinyurl.com/5ffzxsfb

@kiroxford.bsky.social @exposomeimmunology.bsky.social

09.12.2025 17:13 โ€” ๐Ÿ‘ 13    ๐Ÿ” 9    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Post image Post image

Congratulations to our fantastic DPhil student, Henry, for defending his PhD thesis today!! Itโ€™s been a pleasure to have Henry in the lab & we miss him already! Go check out the review (linked below) if youโ€™d like to see some of his work๐Ÿฅณ๐Ÿง‘โ€๐Ÿ”ฌ

@kiroxford.bsky.social

pubmed.ncbi.nlm.nih.gov/40252635/

08.12.2025 16:54 โ€” ๐Ÿ‘ 10    ๐Ÿ” 2    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Weโ€™re very proud of our very own Dr Alice Bertocchi for winning a Kennedy Trust Transition Fellowship! Keep up the amazing work as always, Ali!๐Ÿฅณโค๏ธ

06.12.2025 18:34 โ€” ๐Ÿ‘ 16    ๐Ÿ” 2    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Preview
Postdoctoral Research Assistant - MRC CoRE in Exposome Immunology (183191) You will lead delivery of a CoRE research project, managing your own research and coordinating project activities to meet deadlines. The role includes developing and adapting scientific techniques, an...

We are hiring a Postdoctoral Research Assistant to study how microbiomes influence barrier biology and shape responses to viral infection!

This post is part of the exciting new MRC CoRE in Exposome Immunology.

Apply by December 18 ๐Ÿ‘‡

www.kennedy.ox.ac.uk/jobs/postdoc...

03.12.2025 16:43 โ€” ๐Ÿ‘ 8    ๐Ÿ” 4    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Post image Post image Post image Post image

Day 4 and the final day of the BSI saw a fantastic talk from @labliston.bsky.social about Tregs in the brain and an excellent session devoted to โ€œBarriers, bugs, and breakdownsโ€ - right up our street! Thank you to all organisers and presenters @britsocimm.bsky.social for a great week in Liverpool๐Ÿซถ

06.12.2025 18:30 โ€” ๐Ÿ‘ 20    ๐Ÿ” 3    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Post image Post image Post image Post image

Day 3 of the BSI was a busy one, with Yuqing & Dehui presenting posters, and Ffion giving an excellent talk all about AMR Klebsiella dynamics in the gut! It was also great to see Dave Withers give a fantastic plenary talk!๐Ÿงซ๐Ÿงฌ
@dehuic.bsky.social @yuqinglong.bsky.social
@witherslab.bsky.social

04.12.2025 11:02 โ€” ๐Ÿ‘ 25    ๐Ÿ” 3    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Post image Post image Post image Post image

Day 2 of the BSI saw Gemma & Rachel from the lab presenting posters, as well as the lovely Anna Ahlback from the Maloy lab delivering a great talk on Hh infection and its impact on DSS colitis (go check out their new preprint!)๐Ÿ‘ฉโ€๐Ÿ”ฌ
@gemmala.bsky.social @rachelanscombe.bsky.social @aahlback.bsky.social

04.12.2025 10:17 โ€” ๐Ÿ‘ 18    ๐Ÿ” 4    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Post image Post image Post image

Day 1 of the BSI 2025 on Monday saw the wonderful Judi Allen deliver a fabulous keynote talk! We were also very excited to see Judi share the news of our new MRC Exposome Immunology Manchester/Oxford collaboration๐Ÿ‘ฉโ€๐Ÿ”ฌ
@profjudiallen.bsky.social
@exposomeimmunology.bsky.social
@britsocimm.bsky.social

03.12.2025 12:20 โ€” ๐Ÿ‘ 20    ๐Ÿ” 3    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Post image

Delighted to share that Fiona was awarded the FSI EFIS-IL Lecture Award last week as a keynote speaker at the 56th Annual Meeting of the French Society for Immunology! Weโ€™d like to warmly thank the SFI for the award, it was a pleasure to attend!๐Ÿ‡ซ๐Ÿ‡ท๐Ÿ‘ฉโ€๐Ÿ”ฌ
@sfi-immunologie.bsky.social @kiroxford.bsky.social

21.11.2025 10:57 โ€” ๐Ÿ‘ 27    ๐Ÿ” 8    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
Preview
Oxford and GSK launch Experimental Medicine Collaboration | GSK invests ยฃ10 million over five years to establish the Experimental Medicine Collaboration with the University of Oxford.

Weโ€™re thrilled to share that weโ€™re part of the Experimental Medicine Collaboration (EMC) with GSK! The EMC will put translational science at the forefront of developing treatments for immune mediated inflammatory diseases๐Ÿ‘ฉโ€๐Ÿ”ฌ๐Ÿงฌ๐Ÿงซ

www.ox.ac.uk/news/2025-11...

@gsk.bsky.social @kiroxford.bsky.social

20.11.2025 09:57 โ€” ๐Ÿ‘ 13    ๐Ÿ” 5    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Post image Post image

Some pics from our annual lab autumn walk! We went to the lovely Blenheim palace to get some steps in & enjoy the autumn leaves๐Ÿ๐Ÿšถโ€โ™€๏ธ๐ŸŒณ

04.11.2025 22:10 โ€” ๐Ÿ‘ 14    ๐Ÿ” 5    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Post image Post image

A great afternoon celebrating the award of our MRC CoRE in person. We heard about projects spanning our discovery pipeline, from ExWAS and mechanistic barrier immunology, to potential therapeutic angles for IBD and machine learning for diagnostics.

#exposome #immunology

20.10.2025 10:25 โ€” ๐Ÿ‘ 9    ๐Ÿ” 5    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

@kiroxford.bsky.social @ndorms.bsky.social

29.10.2025 20:55 โ€” ๐Ÿ‘ 2    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Interested in joining the Powrie Lab? Weโ€™re looking for a Postdoctoral Researcher to study the neutralisation capacity of human anti-IL-10 autoantibodies. Youโ€™ll be part of our new MRC CoRE in Exposome Immunology!๐Ÿงซ๐Ÿฆ 

Find out more here & apply by 11th Nov: bulletin.ndorms.ox.ac.uk/c/126QDJVBd0...

29.10.2025 20:55 โ€” ๐Ÿ‘ 14    ๐Ÿ” 16    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

@kiroxford.bsky.social @ndorms.bsky.social

29.10.2025 20:51 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Post image

Throwing it back a few weeks to the final meeting of the CRUK grand challenges optimisticc study! We had a great time in Boston discussing progress in the colorectal cancer & microbiome field - itโ€™s been a real pleasure being part of this group!๐Ÿงซ๐Ÿซถ
@elayton13.bsky.social

27.10.2025 10:05 โ€” ๐Ÿ‘ 11    ๐Ÿ” 2    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Post image

Weโ€™re delighted to hear that our favourite cell type (Regulatory T cells!) have been recognised in the Nobel Prize this year! Huge congratulations to Mary, Fred, and Shimon for their pivotal work in the field & hereโ€™s to many exciting Treg advances to come!๐Ÿฅณ๐Ÿ‘๐ŸŽ‰

07.10.2025 10:37 โ€” ๐Ÿ‘ 34    ๐Ÿ” 5    ๐Ÿ’ฌ 3    ๐Ÿ“Œ 0
Post image

A small primer on the #NobelPrize awarded to Mary E. Brunkow, Fred Ramsdell and Shimon Sakaguchi today. This prize was for combining two separate fields of immunology research - genetic research on IPEX and immunology research of regulatory T cells (#Tregs), with enormous impact on biology/medicine

06.10.2025 11:21 โ€” ๐Ÿ‘ 154    ๐Ÿ” 72    ๐Ÿ’ฌ 2    ๐Ÿ“Œ 12
Preview
Nobel Prize in Physiology or Medicine 2025 The 2025 Nobel Prize in Physiology or Medicine has been awarded jointly to Mary E. Brunkow, Fred Ramsdell and Shimon Sakaguchi โ€œfor their discoveries ...

Happy #treg day everyone - congratulations to Mary Brunkow, Fred Ramsdell, Shimon Sakaguchi and to all the immunologists who have contributed to this incredible field. See our collection: www.nature.com/collections/...

06.10.2025 17:02 โ€” ๐Ÿ‘ 36    ๐Ÿ” 13    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Post image Post image Post image Post image

September meant it was the Powrie labs turn to organise an institute social! We hosted โ€œThe Great Kennedy Bake Offโ€ and had lots of tasty entries, as well as a cake decorating competition! Congratulations to our winners - Lynn for best bake and Osheen for best decorating!๐Ÿฐ๐Ÿช๐Ÿง
@kiroxford.bsky.social

20.09.2025 11:21 โ€” ๐Ÿ‘ 14    ๐Ÿ” 5    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 1

@ndorms.bsky.social @amit-halkhoree.bsky.social @rachelanscombe.bsky.social

19.09.2025 09:31 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

@powrielab is following 19 prominent accounts