The Jackson Laboratory

YouTube video by The Jackson Laboratory How does our circadian rhythm affect our cells? | Gretchen Clark | 2025 JAX Scholar

Clark's practical advice for seasonal affective disorder:
🌅 prioritize morning light,
📱 reduce nighttime screen use,
⏰ and maintain a consistent routine.

See more at: youtu.be/Yue3i6yJBtE?...

YouTube video by The Jackson Laboratory 👋 Meet Gretchen Clark

Gretchen Clark, 2025 JAX Scholar, is exploring how circadian rhythms influence cellular aging—especially the behavior of senescent cells. Her work could unlock new strategies for healthy aging.

Watch her explain the science in this one-minute video: https://youtu.be/oq8lxhudOnE?si=Nd7G235lBtTQ-UeL

a microscopy image of stem cells in the shape of a heart. White text on black reads: Welcome to the CARDIOVERSE. JAX receives an up to $30M contract award to revolutionize drug safety testing with AI-powered "virtual hearts"

Thanks to an up to $30M contract award from ARPA-H, JAX aims to revolutionize drug safety testing with the #CARDIOVERSE—a new project that combines #AI, #stemcells, and #genetic variation to predict #drugsafety before human trials. 💊 🧪 🔬 🤖

go.jax.org/cardioverse

Stronger together: Fueling the future of medicine Our organizations are joining forces to tackle some of the world’s greatest health challenges.

Together, JAX and NYSCF combine strengths in genetics, stem cells and data science to accelerate discovery and deliver solutions that will make a lasting difference for patients around the world. 🧬 🐁 🔬

Beyond Genes: Epigenetics, Environment and Health Gain a basic understanding of genetics versus epigenetics and learn about environmental causes and consequences of epigenetic changes in human and mouse model studies.

🧬 Curious about the difference between #genetics and #epigenetics?

Explore how environment, epigenetics and health intersect with @jacksonlab.bsky.social's free, 1 – 2 hour course: education.learning.jax.org/beyond-genes...

#EpiSci #EpigeneticsSci #Epigenomics

Reprogramming biology: iPSCs and the future of predictive research How patient-derived stem cells and genomic tools are transforming disease modeling and accelerating cures

Reprogramming biology: iPSCs and the future of predictive research

How patient-derived stem cells and genomic tools are transforming disease modeling and accelerating cures 🧬🧪🔬🧫

We are grateful for the incredible people who make our mission possible. From the patients and families who inspire us, to the researchers, partners and supporters who fuel discovery, thank you for being part of the JAX community.

Together, we're advancing science and improving human health.

Search Magazine, Vol. 18, No. 2 - Fall 2025 Search Magazine Fall 2025 A powerful alliance to accelerate the pace of discovery. The Jackson Laboratory & The New York Stem Cell Foundation

Dive into our latest issue of JAX's Search Magazine to read all about the JAX-NYSCF Collaborative and how we're building an integrated discovery platform with #mice, #stemcells, and #AI to transform human health. 🧠 🧪 🔬 🤖 https://online.flippingbook.com/view/661118668/

Reprogramming biology: iPSCs and the future of predictive research How patient-derived stem cells and genomic tools are transforming disease modeling and accelerating cures

Reprogramming biology: iPSCs and the future of predictive research

How patient-derived stem cells and genomic tools are transforming disease modeling and accelerating cures 🧬🧪🔬🧫

As winter approaches, we’re reflecting on the incredible work happening at JAX. Thank you, Commissioner Michael Duguay of the Maine Department of Economic and Community Development, for visiting this week to learn about our work and the impact of state support on our mission to improve human health.

In mice, fertility treatments linked to higher mutations than natural conception While the results do not directly apply to humans, they highlight the importance of understanding how fertility treatments affect an offspring’s DNA.

Mice pups conceived with #IVF in the lab have slightly increased rates of DNA mutations, compared to pups conceived naturally, a new study suggests. 🧬🧪

The results do not directly apply to humans, but highlight the importance of understanding how fertility treatments affect an offspring’s DNA.

What does it take to turn a bold idea into a life-changing treatment? At JAX, innovation is more than progress — it’s the power to transform lives.

Exploring Rare Disease Through Translational Research Learn how mouse models help researchers disentangle the complexity of rare disease and help drive preclinical drug development.

Curious how cutting-edge research is advancing #RareDisease treatment? 🧬

Explore the biology and genetics of rare disease, work through case studies and learn how preclinical research drives therapeutic development in @jacksonlab.bsky.social's 🆓 course: education.learning.jax.org/exploring-ra...

The memory link How lipids can change the course of Alzheimer's disease

The brain is over 50% lipid—but this vital component remains a mystery. JAX scientist Kristen O’Connell uses high-res mass spectrometry to study how these molecules support memory and cognition—and what happens when they don’t. 🧠 go.jax.org/OConnell

Great stuff from @jacobtlevy.bsky.social & Kristen. If you want to learn even more about Kristen & her work, we've got you covered! 5 Minute Genius™ talk: youtu.be/vnZ7zODxFVk?.... And learn more about Kristen on our Maine Science Podcast episode! maine-science-podcast.simplecast.com/episodes/kri...

Long-Read Sequencing Workshop The program will involve sessions on Genome Evolution, Genome Regulation, Transcriptomics, Rare Diseases, Common Diseases, and Viral and Microbial Genomes. Committed speakers include Adam Phillipy (NH...

Join us at this exciting Workshop on #LongReads with keynotes from @aphillippy.bsky.social @mydennis.bsky.social
co-organized by @christinebeck.bsky.social and Mark Adams @jacksonlab.bsky.social Register www.jax.org/longread
#RNA #genomics #bioinformatics #cancer #medicine #evolution #neuroscience

Heading to #SfN25? Don’t miss "Navigating Stem Cell Resources" for a brief intro to stem cell repositories, key models and tools. Presented with @jacksonlab.bsky.social and @simonsfoundation.org.

🗓️ 11/17, 2–3 PM
📍 Room 4
📲 Add to itinerary: https://www.abstractsonline.com/pp8/#!/21171/session/1426

Reprogramming biology: iPSCs and the future of predictive research How patient-derived stem cells and genomic tools are transforming disease modeling and accelerating cures

Reprogramming biology: iPSCs and the future of predictive research

How patient-derived stem cells and genomic tools are transforming disease modeling and accelerating cures 🧬🧪🔬🧫

In his own words, JAX President & CEO Lon Cardon reflects on how the JAX-NYSCF partnership brings together people, ideas and innovation to accelerate discoveries and improve human health. 🧬
https://www.jax.org/news-and-insights/2025/october/the-power-of-3

The memory link How lipids can change the course of Alzheimer's disease

The brain is over 50% lipid—but this vital component remains a mystery. JAX scientist Kristen O’Connell uses high-res mass spectrometry to study how these molecules support memory and cognition—and what happens when they don’t. 🧠 go.jax.org/OConnell

Cancer Education in Under 5 Minutes - YouTube Arm yourself with education to be an informed advocate. These videos, created by The Jackson Laboratory Maine Cancer Genomics Initiative, are geared toward c...

📹 Cancer Education in Under 5 Minutes YouTube playlist:
go.jax.org/5MinuteCance...

Understanding biomarker testing Learn about biomarker testing, its role in cancer care, and how it helps guide personalized treatment options.

🎗️ Patient biomarker education from MCGI: go.jax.org/biomarkers

Precision Oncology Clinical Education

To learn more or support someone on a precision oncology journey:

🎓 Free online courses for researchers and clinicians at any stage from JAX Clinical Education: education.clinical.jax.org/page/precisi...

Biomarker testing + the expertise to interpret results are essential to precision cancer care. MCGI & @jaxeducation.bsky.social are closing the gap to precision oncology.

Get the details: https://go.jax.org/connectingthedots

#CancerBiomarkerDay #GeneticCounselorAppreciationDay 💙

Q&A | Scaling discovery: How iPSCs, automation, and AI are shaping the future of disease research Daniel Paull, who joins JAX from NYSCF as the vice president of discovery and platform development, has spent his career at the intersection of biology and engineering

We sat down with Daniel Paull, JAX's new VP of discovery and platform development, to talk about the JAX-NYSCF Collaborative, the importance of induced pluripotent stem cells, the future of precision medicine, and more. 🧬 🔬 https://go.jax.org/Paull5Q

The memory link How lipids can change the course of Alzheimer's disease

The brain is over 50% lipid—but this vital component remains a mystery. JAX scientist Kristen O’Connell uses high-res mass spectrometry to study how these molecules support memory and cognition—and what happens when they don’t. 🧠 go.jax.org/OConnell

Modeling disease cell by cell - The Jackson Laboratory How JAX scientists are using stem cells to build better models, faster insights and smarter treatments.

From cells to mice to AI-powered insights — JAX is building better models for faster, smarter discoveries. JAX researchers at the forefront of advances in stem cells and cell modeling. 🧬🤖

In his own words, JAX President & CEO Lon Cardon reflects on how the JAX-NYSCF partnership brings together people, ideas and innovation to accelerate discoveries and improve human health. 🧬
https://www.jax.org/news-and-insights/2025/october/the-power-of-3

Building the next generation of genomic thinkers JAX and the University of New England are preparing future health care providers for the era of precision medicine

From rare diseases to cancer care, genomics is already transforming medicine. @jaxeducation.bsky.social and the University of New England are training future clinicians to apply genomic science to real-world care — before they even enter medical school. 🎓 🧬

JAX accelerates Alzheimer’s research through hands-on education New and long-standing workshops at The Jackson Laboratory empower researchers with cutting-edge tools, data, and collaborative opportunities.

🧠 November is #NationalAlzheimersDiseaseMonth, recognizing those working to better understand, support and care for people affected by #Alzheimers.

60+ researchers joined @jacksonlab.bsky.social workshops in 2025 to strengthen the community working to #EndALZ: www.jax.org/news-and-ins...