Breakout Ventures

It's not every day that your portfolio company's CEO 𝒂𝒏𝒅 your firm's Managing Partner land a spot on @cnbc.com 🎉 Congrats to Harshal and the ZymoChem team, and thanks for inviting our very own Lindy to join you on screen!

Clean Start: Startup focuses on making diapers renewable CNBC's Diana Olick reports on one company's attempt to make diapers environmentally friendly.

You can check out the full @cnbc.com clip here: www.cnbc.com/video/2025/0...

It's not every day that your portfolio company's CEO 𝒂𝒏𝒅 your firm's Managing Partner land a spot on @cnbc.com 🎉 Congrats to Harshal and the ZymoChem team, and thanks for inviting our very own Lindy to join you on screen!

Portfolio

And you can always check out our full portfolio of companies building a future powered by science: www.breakout.vc/portfolio/

Navigating the Founder Journey Lessons from Breakout’s inaugural Founder Outpost

Want to know what it takes to launch a science-powered startup? Just ask the founders and advisors doing it!

Thank you to everyone who joined our inaugural Founder Outpost & Campfire. In case you missed it... check out our Medium post for highlights! medium.com/breakoutvc/n...

Twelve | A world made from air™ A world made from air

Dive into how Twelve turns carbon dioxide into essential products: www.twelve.co

Three science-led start-ups making their mark Sometimes research needs to leave academia in order to thrive. Three spin-off founders reveal key drivers of their success.

When your PhD research 𝘭𝘪𝘵𝘦𝘳𝘢𝘭𝘭𝘺 fuels a clean tech revolution... Check out how Twelve's co-founder Etosha (Eee-tah-sha) Cave took her Stanford research out of the lab and into the world to scale tech that converts CO₂ into jet fuel.

www.nature.com/articles/d41...

Noetik Noetik is an AI-native biotechnology company. Our mission is to leverage advanced machine learning methods to discover and develop cancer immunotherapies.

Learn how Noetik is redefining cancer with AI www.noetik.ai

Agenus and Noetik Collaboration Will Predict Cancer Biomarkers Using the Virtual Cell Noetik will use its multimodal AI models to identify which patients will most likely benefit from Agenus’s lead immuno-oncology combination, BOT/BAL.

Congratulations to portfolio company Noetik on their new partnership with Agenus to predict patient outcomes for immuno-oncology treatments. A big step forward for personalized cancer immunotherapies!
www.genengnews.com/topics/artif...

Learn how ZymoChem is building a fossil-free future with biotech: www.zymochem.com

Is there a plastic-free future for your leggings? Activewear relies on synthetics. But as innovators bring stretch denim alternatives to market, important learnings for the sportswear sector could surface.

𝐁𝐚𝐝 𝐍𝐞𝐰𝐬: 80% of our clothing relies on fabrics made from petroleum.
𝐆𝐨𝐨𝐝 𝐍𝐞𝐰𝐬: Bio-based alternatives from companies like ZymoChem are on the horizon!

www.voguebusiness.com/story/sustai...

Learn how Copernic Catalysts develops zero-carbon ammonia solutions that are cost-competitive and quickly scalable: coperniccatalysts.com

Building a Portfolio of Catalysts to Increase the Efficiency of Chemical Production The chemical industry is at a turning point, and Copernic Catalysts is building the technology to lead it—next-generation catalysts that reduce costs, lower emissions, and unlock step-change efficienc...

Ammonia production accounts for ~1% of 𝐠𝐥𝐨𝐛𝐚𝐥 CO₂ emissions. Copernic Catalysts’ tech, developed in collaboration with Schrödinger, could cut that number by half 𝘢𝘯𝘥 create resilient supply chains.

extrapolations.com/building-a-p...

Robotic Orthopedic Systems for Limb Rehabilitation | Phantom Neuro Phantom Neuro revolutionizes robotic orthopedic solutions for limb differences. Regain control, embrace mobility, and embark on a life-changing journey. Explore now!

Learn how Phantom Neuro's MCI system brings natural control to robotic systems in real-world environments: phantomneuro.com/technology/

YouTube video by Austin For America Assistive Technologies for Independence: Robotics and Neural Interfaces Improving Life Quality

What do you get when you combine robotics, AI, and implantable devices? With Phantom Neuro's tech, "You 𝘵𝘩𝘪𝘯𝘬 about closing your hand, and the robotic hand closes."

Hear more from Phantom Neuro's CEO and Founder, Connor Glass, on the Austin4America stage www.youtube.com/watch?v=_tcd...

Dig into how ShiraTronics, Inc. is restoring the quality of life for people living with Chronic Migraine: shiratronics.com

2025 Best Tech Startups in Minnesota - The Tech Tribune The Tech Tribune staff has compiled the very best tech startups in Minnesota. In doing our research, we considered several factors

Congratulations to Chronic Migraine-defeating company ShiraTronics, Inc. for landing a top spot in The Tech Tribune's Best Tech Startups in Minnesota!
thetechtribune.com/10-best-tech...

Modern Meadow | Solutions Businesses and brands are changing industries with biofabricated materials they never could have imagined—until Modern Meadow made them possible.

Learn more about Modern Meadow's scientific approach to greening one of humanity's original art forms (read: clothing): modernmeadow.com/biomaterials

Biofabrication at Scale: Modern Meadow's Sustainable Materials Modern Meadow CEO David Williamson shares how biofabrication is shaking up the world of materials.

Nobody wants to choose between updating their wardrobe and protecting our planet. Scaling their biotech-powered materials, Modern Meadow leads the charge to meet consumers' sustainability demands.

www.rinnovabili.net/business/fas...

Twelve | A world made from air™ A world made from air

Learn how Twelve is creating a world made from air at twelve.co

United Bets on Photosynthesis and Limestone to Fuel Net-Zero Flight Path The Chicago-based carrier has partnered with a number of clean-tech startups in recent months in an effort to meet its climate goals

Nature inspires aviation, from mechanics to aerodynamics. Breakout's portfolio company Twelve is taking this one step further with its "𝘪𝘯𝘥𝘶𝘴𝘵𝘳𝘪𝘢𝘭 𝘱𝘩𝘰𝘵𝘰𝘴𝘺𝘯𝘵𝘩𝘦𝘴𝘪𝘴" tech that turns CO₂ and water into jet fuel. And giants like United Airlines are jumping on board.

Cytovale: Sepsis Medical Device Cyotvale offers IntelliSep, an FDA-cleared early sepsis detection test powered by the Cytovale System medical device.

Learn how Cytovale is setting the new standard for sepsis diagnosis at cytovale.com

ICU-Level Care Not Definitive Indicator for Sepsis, New Study Shows /PRNewswire/ -- A retrospective analysis of an observational study being presented this week at the Society of Hospital Medicine (SHM) Converge conference...

A new 5-year analysis of patients at Our Lady of the Lake Regional Medical Center found that 57% of septic patients identified by Cytovale's 8-minute test 𝘸𝘰𝘶𝘭𝘥𝘯’𝘵 have been flagged by traditional ICU-level triage.

www.prnewswire.com/news-release...

Portfolio

Want to get to know what we do and how we do it? The proof is in the pudding.

Go check out our portfolio, dig into our founders' incredible stories of turning research into reality, and see for yourself.
www.breakout.vc/portfolio/

Why do we use our socials to talk about our founders so much? It's pretty simple.

We could describe how Breakout finds and supports early-stage companies building the future of science. We could use catchy adjectives like "founder-friendly" or "deeply experienced"

Or... we could just show you.

PS - in case you were wondering, a petabyte is equivalent to 1,000 terabytes (TB) or 1,000,000 gigabytes (GB)!

Noetik Noetik is an AI-native biotechnology company. Our mission is to leverage advanced machine learning methods to discover and develop cancer immunotherapies.

Learn more about Noetik at www.noetik.ai, and be sure to stop by their poster at the @theaacr.bsky.social #AACR25 meeting.

How do you turn a 𝘱𝘦𝘵𝘢𝘣𝘺𝘵𝘦 of tumor data into a new cancer therapy? With a nimble team, enormous datasets, and some seriously powerful AI.

Meet Breakout company Noetik, an AI-native biotech using machine learning to redefine how we understand and treat cancer.

And learn how Checkerspot is using biology to build an easier path to the hardest ingredients to source: www.checkerspot.com

Fats from fermentation: Checkerspot unveils high-oleic palm alternative… without genetic modification Checkerspot has developed a Non GMO algal oil in a fermentation tank with the performance of high-oleic palm oil.

Palm oil is everywhere, but what if we could keep the functionality without the deforestation and saturated fats? If your first thought is to create a GMO... we have a better idea. Say hello to the future of fermentation with Checkerspot.

Read the AgFunder article:
agfundernews.com/fats-from-fe...