Calamitous Rex

The structure of the human sweet receptor bound to artificial sweeteners reveals the structural basis for sweet detection, shedding light at how one single receptor mediates responses to a range of sweet-tasting compounds. ow.ly/M39P50VPqfT @fitzpatricklab.bsky.social 🧪

He was sick for so long but he wasn't old and he was a stubborn fighter. Another piece of my chosen family passing to the ether, and I'm torn between grief and relief he's out of pain. It's a duller, confusing ache

NASA satellite spies Curiosity chugging along on Mars The car-sized rover averages about 98 feet per hour.

Look at 'em go!

Chug! Chug! Chug! Chug!

www.popsci.com/science/curi...

I can generally tell the difference between a joke scold and the ones who actually mean it, but when in doubt I err on the side of "you mean it." Remember always also that "the failure mode of 'clever' is 'asshole.'"

The freight guys have really started freaking out over the past 48-72 hours:

A collage photo, the left of "Mosquito: southern vampires" by Marita Woywod Crandle. Right photo of a bright orange dress with flowers, neon orange leggings and a colourblock cardigan

1 day it's "we thought of you!" for vampire fiction from New Orleans from neighbours, the next day it's my bright af outfit being therapy for a gloomy day from a stranger. I love that these 2 XPs were 12hrs apart 🤪 #boutiquedevampyre #colorfulfashion

The great melting pot is officially losing its dang mind as a gov and people are starting to act on that

Now I'm even getting Ms.Frizzle commentary when I buy fabric for a skirt at JoAnns (it's super sucky they're closing btw). I'm not mad about it lol #magicschoolbusfashion

blue sky is supreme because every time you post you get 100 school principals in the replies asking to see you in their office

The really scary thing is, 10¢/word is pretty decent money 112 years later.

My library's book club title this month was "Annie Bot" by Sierra Greer. Very good in a Seriously Disturbing way. Rewatching Voyager S6E11, I was struck by unlikely parallels of Janeway & Doug...& grateful for those Trekkie moral compasses, whew #BookSky #TrekSky #AIethics

If a reader dislikes your politics, then no amount of subtlety will prevent them from accusing your story of not being subtle enough. Not even if the politics of the story are about your right to live. Don’t go quieter to appease the callow.

As always, @chriswarcraft.bsky.social is a real one.

Works as advertised

As Kluwe said, "Remember - peaceful civil disobedience, and no kings, no tyrants. Not ever."

Way to be a true patriot, @chriswarcraft.bsky.social !

I appreciate everyone’s messages of support, I’m trying to get through all my mentions but as you can imagine, it’s been a bit of a busy day :)

Remember - peaceful civil disobedience, and no kings, no tyrants. Not ever.

Good for them!

All right, no more lying in bed doing nothing. Time to get up, go to my office desk, and do nothing there!

It's frustrating having nebulous error messages on hiring sites - which turn out to be for using a GVoice #. Maybe I don't want all of y'all to have my direct mobile, that should Not be a blocker to apply #jobsearch #hiring #privacy

Roman expansion linked to 5,200-year-old lead pollution, study finds Researchers discovered lead contamination linked to early metallurgy in the Aegean region.

Humans, sheesh
#bronzeage #archeologysky #pollution #history

m.jpost.com/archaeology/...

A photo of a cat food bowl with 3 types of food in a row, similar to neopolitan ice cream. Dry kibble left, wet food middle, rehydrated raw pellets on the right

Signs of a spoiled #cat: neopolitan breakfast. The Manager wouldn't have it any other way

I can't recall a single point in my life where I've been scared of a trans person.

Unfortunately, I can think of many, many times that I've been scared FOR trans people.

So far, the run up to birthday 40 is pretty terrible. Guess I should have expected that for 2025...

If you’re in an institution doing any kind of DEI work, the most important thing to do right now is simply call it something else. Change it to “Community Outreach” & then keep on doing the same important work. When they outlaw Community Outreach rebrand it as “Strategic Partnerships,” rinse/repeat.

David Lynch in sunglasses saying "i hope you all are having a lot of fun working on your favorite projects"

Honor his memory by doing something strange, unraveling a riddle within yourself, and working on your favorite projects.

Arthur's sister from the PBS show Arthur holds a library card in a library catching reads now I know what power feels like

Fight fascism, get a library card.

It would be nice if the new forced office closure for next holiday season didn't require me using my PTO allotment, esp since it doesn't cover solstice & idgaf about NYE 🙃

A photo of a 1931 hardcover of Mark Twain's "adventures of Tom Sawyer"

A photo of the inside title pages of a 1931 hardcover of Mark Twain's "adventures of Tom Sawyer"

A photo of the inside dedication of a 1931 hardcover of Mark Twain's "adventures of Tom Sawyer". The message says "To Eric, From Aunt Sarah. Tewksbury, Massachusetts U.S.A 1932

On a work trip and single day off plans got waylaid by #Darragh, wandered Bristol ENG and found this pretty old thing to take back to its origin (NewENG)
#marktwain #antiques #booksky

Every single time I gain weight, random people ask if I've lost weight. It's the weirdest thing..!

I use custom #StoryGraph tags to delineate the source of the book (libby, hoopla, mylibrary, etc) as well as if it's something I'm reading for a book club or other specific impetus that isn't a challenge