π Launch your career in advanced gene and cell therapies! π
RAREFIND #MSCA-COFUND #PhD Programme opens its call for applications!
πKnow more and apply now: www.rarefind-cofund.eu
#RAREFINDPhD
@tigem.bsky.social
The Telethon Institute of Genetics and Medicine (TIGEM) is a Telethon Foundation research center located in Pozzuoli (Italy) that aims to help people with rare genetic disorders across the world.
π Launch your career in advanced gene and cell therapies! π
RAREFIND #MSCA-COFUND #PhD Programme opens its call for applications!
πKnow more and apply now: www.rarefind-cofund.eu
#RAREFINDPhD
Join our lab dibernardo.tigem.it for the #ERC-funded project DIMERCIRCUITS at @tigem.bsky.social. We are building synthetic gene circuits to power next-generation gene and cell therapies. We are looking for candidates with a PhD in #SyntheticBiology or related. Apply by email: dibernardo@tigem.it
10.09.2025 10:36 β π 2 π 2 π¬ 0 π 0#genetherapy #celltherapy #geneediting #genomics #molecularmedicine #proteindesign #syntheticbiology #AI-basedproteinengineering #computationalbiology #molecularimmunology
03.06.2025 10:50 β π 0 π 0 π¬ 0 π 0π Group Leader positions at TIGEM: www.tigem.it/newsroom/car...
π Group Leader positions at San Raffaele Telethon Institute for Gene Therapy (SR-Tiget): back.fondazionetelethon.it/uploads/2025...
π Postdoctoral Fellowships at TIGEM & SR-Tiget : back.fondazionetelethon.it/uploads/2025...
π’ Global Call for Scientific Talent β Join the #FondazioneTelethon Institutes!
We're looking for exceptional scientists to join #TIGEM and #SR-Tiget, two world-class research centers at the forefront of innovation in #genetherapy, #celltherapy, #geneediting, #genomics, and #molecularmedicine.
Back From #ASGCT!!!
TIGEM was pleased to take part in the ASGCT Conference 2025, where we had the opportunity to present our latest research and engage with the gene and cell therapy community!
@asgct.bsky.social
π Attending #ASGCT2025 in #NewOrleans?
Donβt miss this Scientific Symposium hosted by the Coalition of International Gene Therapy Societies:
π Clinical Trials Around the Globe
ποΈ [Today, May 16th]
π 8:00 AM β 9:45 AM
π Room 293β296
#GeneTherapy #ASGCT #AAV #Retina #LiverGeneTherapy #RareDisease
#MPSAwarenessDay #MPSVI #GeneTherapy #RareDiseases #LysosomalDisorders #TIGEM #FondazioneTelethon #MEUSIX #ClinicalTrials #TranslationalResearch #HopeForRare
15.05.2025 16:38 β π 0 π 0 π¬ 0 π 0π Thanks to Fondazione Telethon, a new trial phase is underway β testing a higher dose and pushing us closer to real impact.
π Deep gratitude to the MPS community for their strength and partnership.
𧬠Through the MEUSIX project with @biomarinpharma.bsky.social and @ec.europa.eu funding, we launched the first AAV-based gene therapy trial for MPS VI β showing promising safety and efficacy. Why gene therapy?
Because current treatments fall short. We aim for a one-time, lasting solution.
ποΈ Itβs MPS Awareness Day.
At TIGEM, we stand with patients β especially those with MPS VI (Maroteaux-Lamy syndrome), a rare lysosomal disorder caused by ARSB gene mutations.
π’Applications for SEMM PhD program are now open! π
We have 2 open positions at TIGEM in the PhD program in Systems Medicine.
Deadline: June 9th β donβt miss it!
Apply here: www.semm.it/education/ho...
#PhD #SystemsMedicine #TIGEM #SEMM #PhDOpportunity #BiomedicalResearch #CallForApplications
ποΈ August 11β12, 2025 | Irvine, California
π§ Abstract submissions open until April 28!
π Info & registration: www.aiche.org/sbe/conferen...
#mSBW2025 #SyntheticBiology #GenomicMedicine
Excited for the International Mammalian Synthetic Biology Workshop (mSBW2025) β the only conference fully focused on mammalian synthetic biology! π§¬
Meet top experts, including @diegodibi.bsky.social, Genomic Medicine Program Coordinator at TIGEM and part of this yearβs Organizing Committee.
#PompeDay #RareDiseaseResearch #GeneTherapy #Tigem #FondazioneTelethon #LisosomalStorageDisorder
15.04.2025 13:35 β π 0 π 0 π¬ 0 π 0Our journey began with science and compassion, inspired by the story of Rossella and a life-changing connection between Dr. Giancarlo Parenti and John Crowley in 2002 β a reminder that research, collaboration, and care can transform lives.
Read the full story here: www.tigem.it/newsroom/new...
from biomarkers discovery and lysosomal biology insights to innovative gene therapy and chaperone-based approaches.
15.04.2025 13:35 β π 0 π 0 π¬ 1 π 0Today we mark #InternationalPompeDiseaseDay, raising awareness for this rare genetic disorder. At TIGEM, supported by #FondazioneTelethon, we combine genetics, molecular biology, clinical research, and patient advocacy to advance new therapies β
15.04.2025 13:35 β π 0 π 0 π¬ 1 π 0Excited to share the latest work of Pastore group!
Loss of Folliculin drives liver cell damage and cholangiocarcinoma via MiT/TFE activation.
π Read the full article: doi.org/10.1038/s414...
#StructuralBiology #AI #GeneTherapy #RareDiseases #ProteinDesign
02.04.2025 13:35 β π 0 π 0 π¬ 0 π 0π‘ "TIGEM gave me the chance to return to Italy and make a difference. I want to push the boundaries of research on rare diseases."
Big things ahead for Andrea and his mission to advance molecular therapies! π
Read the interview here: www.tigem.it/newsroom/new...
π¬ From Sweden to Italy: @andpdb.bsky.social is bringing his expertise in Computational Structural Biology back home!
After working at #KTH (Stockholm), heβs now a Staff Scientist at TIGEM, using AI and physics-based models to design hyperactive enzymes that improve gene therapy for rare diseases.
A huge thank you to everyone who participated! Letβs keep building bridges between science, finance, and the future. πβ¨
#HydeParkCoroglio #Innovation #ScienceAndFinance #Collaboration #Future
Read more here: www.linkedin.com/feed/update/...
He shared valuable insights on #research and #biotech, exploring the potential of innovation and the challenges ahead. The discussion also covered key financial strategies supporting cutting-edge research, demonstrating how #techtransfer can turn discoveries into real-world impact.
02.04.2025 08:48 β π 0 π 0 π¬ 1 π 0π Exciting moments at #HydeParkCoroglio!
Our Prof. Alberto Auricchio, Scientific Director at Tigem in Pozzuoli, took the stage for an inspiring talk.
π¬ AAV-based gene therapy for Stargardt disease is safe and effective in large animal models
A work of #IvanaTrapani and #AAVantgardeBio !!!
π #ScienceAdvances | doi.org/10.1126/sciadv.adt9354
#GeneTherapy #Ophthalmology #AAV #Stargardt #VisionResearch
Low doses? π― Boost memory.
High doses? π« Impair it.
A game-changer for cognitive enhancement strategies in schizophrenia and beyond!
πRead the full article here: doi.org/10.1038/s414...
#Neuroscience #Memory #Dopamine #Striatum #PKA #Schizophrenia #SystemsPharmacology
πNew Research Alertπ
π§ Cutting-edge neuroscience from De Leonibus' group, now in #NatureCommunications!
This study reveals how different doses of D1 dopamine agonists bidirectionally regulate memory capacity via fronto-striatal cAMP/PKA signaling in mice.
π£ We are hiring!!! π£
Don't miss your chance to join TIGEM and be part of groundbreaking research! π¬
π¨Exciting Postdoctoral Opportunity in Gene Therapy & Genome Editing! π¨
π www.tigem.it/newsroom/car...
π¨Research Technician in Gene Therapy & Genome Editingπ¨
π www.tigem.it/newsroom/car...
Here is our latest paper in @commsbio.bsky.social We reveal a two-phase TFEB nuclear shuttling driven by calcium release and mTORC1 inhibition, using microfluidics & quantitative modelling. Kudos to Iacopo Ruolo & colleagues@snapolit.bsky.social @tigem.bsky.social
www.nature.com/articles/s42...