Francesca Ciccarelli's Avatar

Francesca Ciccarelli

@ciccarellilab.bsky.social

We study the drivers of cancer evolution from initiation to response to therapy. We are part of the Centre for Cancer Evolution at Barts Cancer Institute and the Francis Crick Institute in London, UK. Posts from Francesca

542 Followers  |  394 Following  |  48 Posts  |  Joined: 13.11.2024  |  1.9168

Latest posts by ciccarellilab.bsky.social on Bluesky

πŸ˜‚ its more rock’n’roll though πŸ˜‚

08.10.2025 09:09 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Post image

First time I give a talk literally in a football stadium 😎⚽️

08.10.2025 08:24 β€” πŸ‘ 6    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
Post image

Beautiful Bilbao

07.10.2025 18:10 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Post image

Our first Centre for Cancer Evolution PI retreat! A wonderful day at Goodenough House discussing science, strategy and forging new collaborations @qmbci.bsky.social

01.10.2025 12:00 β€” πŸ‘ 6    πŸ” 3    πŸ’¬ 0    πŸ“Œ 0
Post image

Great science and good fun at the faculty retreat of the Centre for Cancer Evolution @qmbci.bsky.social. Here @stuartmcdonald.bsky.social explaining his big question!

01.10.2025 10:56 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Appennine mountains in Abruzzo, central Italy. Highly recommended

15.08.2025 06:43 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Post image

Peaceful early morning

15.08.2025 06:03 β€” πŸ‘ 3    πŸ” 0    πŸ’¬ 2    πŸ“Œ 0
Post image

Midsummer night πŸŒŸπŸŒ™

03.07.2025 22:19 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Preview
Induction of a mismatch repair deficient genotype by tailored chemical mutagenesis in experimental models of cancer Mismatch repair deficient (MMRd) tumors harbor thousands of somatic mutations enriched for insertion–deletion (indels) conferring high sensitivity to …

This is an important milestone: mutagenic drugs can increase TMB and induce a dMMR-like genetic profile, but do not improve response to immunotherapy in pMMR CRC patients. Some evidence of TIME remodelling, but likely not in the direction needed fro response... www.sciencedirect.com/science/arti...

14.06.2025 05:23 β€” πŸ‘ 6    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0

Great meeting and great questions! Thanks for inviting me!

28.05.2025 11:52 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Post image

Our very own @mirjana-efremova.bsky.social (very small compared to the very huge screen) speaking about her beautiful data on cell plasticity in cancer mets at the #Beatson International Cancer Conference. @qmbci.bsky.social @cruk-mi.bsky.social

27.05.2025 11:03 β€” πŸ‘ 15    πŸ” 4    πŸ’¬ 0    πŸ“Œ 0
Post image

La Caixa panel dinners are always a treat! View of Barcelona from the museum of Catalan art

22.05.2025 18:51 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Post image

I spent two days meeting students and faculty & delivering the keynote speech at the London Health Research Day @westernu.bsky.social. I truly enjoyed the enthusiasm and genuine engagements of the young generation of cancer researchers! Thanks @ggloor.bsky.social & colleagues for inviting me!

15.05.2025 00:10 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
Post image Post image

Street crossing in London, ON πŸ¦†πŸ¦†πŸ¦†

14.05.2025 21:53 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Post image Post image

Gorgeous day in NYC

11.05.2025 21:04 β€” πŸ‘ 5    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Thanks for inviting. It was fun!

12.03.2025 08:26 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Post image Post image

Familiar faces in Belfast! Enjoyable time at the meeting of the Irish Association for Cancer Research! @qmbci.bsky.social

07.03.2025 14:02 β€” πŸ‘ 5    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
Post image

Next Thu 13th March Ilaria Malanchi @ila07.bsky.social and I will host the next "Medicine at the Crick" event focusing on how tissues evolve over time and why this may initiate disease. Free in person/virtual registration @crick.ac.uk: www.eventbrite.co.uk/e/medicine-a...

05.03.2025 14:46 β€” πŸ‘ 7    πŸ” 2    πŸ’¬ 0    πŸ“Œ 1

Dear Volodymyr Zelenskyy, dear Ukrainian friends, you are not alone.

28.02.2025 19:31 β€” πŸ‘ 23288    πŸ” 5825    πŸ’¬ 445    πŸ“Œ 280

We have two open positions for #computationalbiologists to work on:
1. Early cancer initiation following our work in #NatureCancer (Ref 5028)
2. Response to cancer immunotherapy following our work in #CancerCell (Ref 5073)
To apply use the provided reference numbers: www.qmul.ac.uk/jobs/vacanci...

19.02.2025 18:08 β€” πŸ‘ 1    πŸ” 3    πŸ’¬ 0    πŸ“Œ 0

Beautiful cover 😍 from an idea of our own @pedrandrei.bsky.social! Credits to Joe Brock from @crick.ac.uk

11.02.2025 09:14 β€” πŸ‘ 13    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0

Very timely publication on World Cancer Day and spot on title considering the times we live in. I am very proud of all wonderful colleagues that dedicate their talent to understand, treat and eventually cure cancer @qmbci.bsky.social πŸ’ͺπŸ’ͺπŸ’ͺ

04.02.2025 17:13 β€” πŸ‘ 6    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
Post image Post image Post image Post image

Really enjoyed @mirjana-efremova.bsky.social talk on phenotypic plasticity in #ColorectalCancer

Super clear explanation of role of key genes ( #LRIG1 etc) in cell switch

@qmbci.bsky.social
@ciccarellilab.bsky.social
@drtanyasoliman.bsky.social
@mcclellandlab.bsky.social
@sibucz.bsky.social

29.01.2025 15:21 β€” πŸ‘ 9    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
Post image Post image Post image

Cool to be at #FoG2025 @fogenomics.bsky.social

A bit more #SpatialGenomics content this year which is great!

Surprise visit from #Darth & #Chewbacca!

@ciccarellilab.bsky.social @mirjana-efremova.bsky.social
@karlsmithbyrne.bsky.social
@qmbci.bsky.social
@omaiques.bsky.social

29.01.2025 12:58 β€” πŸ‘ 8    πŸ” 3    πŸ’¬ 1    πŸ“Œ 0

Wait for me!! 😊

29.01.2025 13:46 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Post image

Great talk from Hrvoje Misetic on the context dependent role of Cdkn2a in cancer evolution @qmbci.bsky.social @cruk-cityoflondon.bsk.social. Well done πŸ‘πŸ’ͺπŸ‘Œ

28.01.2025 15:02 β€” πŸ‘ 4    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
Post image

Nathaniel MonPere from @benjaminwerner.bsky.social lab in the Centre for Cancer Evolution @qmbci.bsky.social modelling #clonalhaematopoiesis in ageig at the Annual Symposium of @cruk-cityoflondon.bsky.social

28.01.2025 14:06 β€” πŸ‘ 7    πŸ” 3    πŸ’¬ 0    πŸ“Œ 0
Post image

With Ilaria Malanchi @ila07.bsky.social we will host the #MedicineattheCrick event (13th March at the Crick @crick.ac.uk.) Join world experts to discuss how early mutant cells interact with surrounding niche to maintain homeostasis or start cancer. Free registration! Details in the poster πŸ‘‡

25.01.2025 09:45 β€” πŸ‘ 26    πŸ” 8    πŸ’¬ 0    πŸ“Œ 0
Post image

Strong Barts representation at the Cancer Research Nottingham Annual Symposium! @francesbalkwill.bsky.social @qmbci.bsky.social @uniofnottingham.bsky.social

24.01.2025 15:26 β€” πŸ‘ 5    πŸ” 2    πŸ’¬ 0    πŸ“Œ 1
Post image

Hi all, our lab will soon recruit a PhD student working within a very exciting MSCA Horizon Doctoral network working on ageing, UNION, which gathers some fantastic scientists. Please apply if your profile fits our project (see attached advert).
Looking forward to working with you!

23.01.2025 08:37 β€” πŸ‘ 38    πŸ” 35    πŸ’¬ 0    πŸ“Œ 3

@ciccarellilab is following 20 prominent accounts