Riham Smoom

Another piece in the puzzle of telomere biology disorders and pulmonary fibrosis - well done to the Tzfati and @kaminskimed.bsky.social teams.

Beautiful paper!

#CureIPF
#MedSky
#SciSky

The house mouse maintains constant telomere length throughout life Abstract. Telomeres protect the chromosome ends from deleterious DNA damage response and repair activities. In humans, telomerase maintains telomere length

According to dogma mammalian telomeres shorten with age.
This paper shows that mouse telomeres do not shorten with age. Should we revisit the paradigm?
Kudos Drs Smoom, Tzfati & team!!!
#ScienceMattets
academic.oup.com/nar/article/...

The house mouse maintains constant telomere length throughout life Abstract. Telomeres protect the chromosome ends from deleterious DNA damage response and repair activities. In humans, telomerase maintains telomere length

Do mouse telomeres shorten with age? 🐀
Our study, started in 2019, is now out in NAR! @narjournal.bsky.social 🎉
We show that house mouse telomeres stay stable with age — at least in blood and tail!

Thanks to Professors Tzfati & Kaestner and everyone who made this possible! 👇
doi.org/10.1093/nar/...