Thank you to NCCN, Sumitomo Pharma, Pfizer Oncology, and Bayer Oncology for supporting CLEARED (Comeback from Long CoursE ADT with RElugolix and Darolutamide). www.urologytimes.com/view/nccn-aw...
27.11.2024 22:13 β π 0 π 0 π¬ 0 π 0@atishchoudhury.bsky.social
Medical Oncologist Lank Center for Genitourinary Oncology Dana-Farber Cancer Institute Views expressed herein are my own https://scholar.google.com/citations?user=sJ4jYT0AAAAJ&hl=en
Thank you to NCCN, Sumitomo Pharma, Pfizer Oncology, and Bayer Oncology for supporting CLEARED (Comeback from Long CoursE ADT with RElugolix and Darolutamide). www.urologytimes.com/view/nccn-aw...
27.11.2024 22:13 β π 0 π 0 π¬ 0 π 0Now activated! CLEARED will enroll pts with high-risk localized, lymph node-positive or low volume HSPC (planned for treatment interruption) to receive 2 years of relugolix+darolutamide for PK studies of the combo and to assess T recovery after completion. clinicaltrials.gov/study/NCT064...
27.11.2024 22:10 β π 2 π 0 π¬ 1 π 0It's not too late to join our contribute to our team at movember.com/t/bellissimo to support Movember's efforts towards prostate cancer, testicular cancer and mental health research and resources.
24.11.2024 12:53 β π 0 π 0 π¬ 0 π 0See you at Kings Back Bay on Monday 11/25/24 from 6-10 pm for BellissiMOβs Movember Fundraising Finale. There will be food, karaoke, and celebration!
24.11.2024 12:52 β π 0 π 0 π¬ 1 π 0On multivariable analysis, duration of treatment >=12 months was independently associated with cPFS after T recovery, provocatively suggesting that prolonged systemic therapy could sterilize (or render permanently dormant) micrometastatic disease and lead to "cure" in a subset.
24.11.2024 12:30 β π 0 π 0 π¬ 0 π 0Of note, 3-year cPFS after T recovery for patients receiving "total therapy" was 51% for those who received >=12 mo ADT, and the swimmer's plot shows patients out to > 10 years after T recovery.
24.11.2024 12:30 β π 0 π 0 π¬ 1 π 0Can oligometastatic prostate cancer be cured with "total therapy" including radiation to all sites of disease and hormonal therapy? Dr. Praful Ravi and I along with colleagues at Dana-Farber present data from our cohort. www.sciencedirect.com/science/arti...
24.11.2024 12:29 β π 4 π 0 π¬ 1 π 0