Lena Skrutl

self-awareness is such a scam bc now i can see all my problems AND i still have them? rude

22.02.2025 18:13 — 👍 718    🔁 132    💬 3    📌 4

The fact of the matter is that Black, Indigenous, Latino/a, LGBTQ+, and other minorities groups in the US have worse health than white, cis, heterosexual people. Not studying the problem won't make the difference go away. Studying how and why it happens and making policies based on facts will. /fin

14.02.2025 11:58 — 👍 42    🔁 15    💬 0    📌 0

Conservatives have pushed hard the idea that there is science corruption-- because they want to destroy science and universities.

There are some problems with some scientists. But the science system is still great. Letting conservative elites tear it down to enrich billionaires wld be a disaster.

14.02.2025 16:46 — 👍 51    🔁 11    💬 2    📌 0

If you have been affected by the fires in LA, or are concerned about your ability to keep precious Drosophila strains going during the latest funding crisis, we will host your strains as a backup. Please email me.

Please amplify. If you are also able to host fly strains, add your name as well.

28.01.2025 21:45 — 👍 797    🔁 606    💬 12    📌 30

Loss of D1 during embryogenesis triggers transposon expression in adult ovaries. Top: Ovaries from the indicated genotypes (D1 and aubergine mutants and heterozygotes, F1 and F2) were stained with Vasa (green) and DAPI (magenta). Bottom: RNA in situ hybridization against Copia (green) and total polyadenylated mRNA (blue) was performed in ovaries of the indicated genotypes that were also stained for DAPI (magenta). Yellow and black arrowheads indicate undifferentiated germ cells in the aubergine mutant germarium.

Pericentromeric #heterochromatin clusters into chromocenters. @skrutlnize.bsky.social &co use quantitative mass spec to characterize the chromocenter proteome in multiple tissues, identifying a link between satellite DNA-binding proteins & #transposon repression🧪 @plosbiology.org plos.io/4akuNAi

17.01.2025 10:39 — 👍 111    🔁 10    💬 3    📌 1

We are pleased to report publication of the Drosophila circadian clock connectome in @naturecomms.bsky.social. Check out the final version for additional analyses not present in the preprint. @unrcabnr.bsky.social www.nature.com/articles/s41...

06.01.2025 19:03 — 👍 41    🔁 13    💬 2    📌 1

This is not a drill, British Meiosis Meeting 2025 will be in Liverpool 🎉. Join us on 26-27 of March docs.google.com/forms/d/e/1F...
Abstract deadline 20th Feb. Most talks reserved for ECRs (PhDs, Post-Docs & NewPIs)! With an amazing keynote Joao Matos. @meiosis4eva

16.01.2025 07:21 — 👍 31    🔁 13    💬 0    📌 0

Also super happy to share our #Meiosis preprint! We show that satDNA mismatches disrupt meiotic pairing, especially at centromeres, leading to oocyte death. This highlights the critical role of satDNA in maintaining meiotic stability
👉 researchsquare.com/article/rs-5538025/v1 !

Jagannathanlab.com

16.01.2025 15:31 — 👍 6    🔁 0    💬 2    📌 0

Multi-tissue characterization of the constitutive heterochromatin proteome in Drosophila identifies a link between satellite DNA organization and transposon repression Pericentromeric heterochromatin clusters into nuclear foci known as chromocenters, the proteome of which remains largely unknown. This study uses quantitative mass spectrometry to characterize the chr...

Thrilled to share our paper is out in @plosbiology.org! 🎉 We explore how satellite DNA organization is linked to transposon repression. A huge thanks to my amazing co-first author Ankita Chavan and all the collaborators who made this possible! 💕

jagannathanlab.com
#Proteomics

Check it out here 👇👇

16.01.2025 15:15 — 👍 29    🔁 10    💬 1    📌 1

Loss of D1 during embryogenesis triggers transposon expression in adult ovaries. Top: Ovaries from the indicated genotypes (D1 and aubergine mutants and heterozygotes, F1 and F2) were stained with Vasa (green) and DAPI (magenta). Bottom: RNA in situ hybridization against Copia (green) and total polyadenylated mRNA (blue) was performed in ovaries of the indicated genotypes that were also stained for DAPI (magenta). Yellow and black arrowheads indicate undifferentiated germ cells in the aubergine mutant germarium.

Pericentromeric #heterochromatin clusters into chromocenters. @skrutlnize.bsky.social &co use quantitative mass spec to characterize the chromocenter proteome in multiple tissues, identifying a link between satellite DNA-binding proteins & #transposon repression🧪 @plosbiology.org plos.io/4akuNAi

16.01.2025 13:13 — 👍 14    🔁 10    💬 1    📌 0