Dave Weisman

Sad. These men and women fought for better.

"Irrespective of one's stance on the clinical efficacy of lecanemab.." What does this even mean? We have the data that shows the efficacy.

Earned that poutine.

I love Canada. Got to speak at the CAGP-CCSMH 2025 Annual Scientific Meeting.

Wait till they find out how doctors used to treat syphilis.

Intranasal Oxytocin for Managing Agitation in a Patient of Mixed Dementia With Multiple Pathologies, Particularly With a History of Repetitive Head Injuries - Naresh Jadav, Sümeyye Kuş, James Ellison,... Background Agitation is common in persons living with dementia (major neurocognitive disorder) and worsens with disease progression. Brexpiprazole is the sole F...

Weird case of Oxytocin helping with agitation.

journals.sagepub.com/doi/10.1177/...

Go Sid!

He’s almost moving from a werewolf to aware wolf.

This will be the first winner of the Ig-Nobel and the Nobel.

Wrapping up Vermont riding.

Join me in burning out more doctors.

It is a trap.

if you don’t laugh, you cry.

Awesome.

Meh, drop out over time will make the stats eventually overlap. You can make your point then. But 1.5 years of delayed treatment, then the lines look parallel to me.

Great piece. I hope eventually @profrobhoward.bsky.social will turn sanguine.

Then try to get NHS to pay for it. Because currently how many people in the UK are getting it? How many of them are URM by any measure?

How lithium went from 7Up to treatment for mental illness — and maybe Alzheimer’s A new study suggests lithium may play a crucial role in developing Alzheimer’s treatments, but the substance has long been used to treat mood disorders like bipolar disorder.

Another mouseheimer's paper blown up beyond all reason. Please, do not take Lithium for memory or Alzheimer's disease.

wapo.st/47uJMrU

This is probably much better than 10 years ago. Still bad, but getting better.

Does he know what productivity means? I can't point to a single advancement he made, helped with, or even a failed try.

Hilarious photo.

I think I just saw Dr. Offit IRL during a mtn bike ride. I nodded but didn't approach because it would have been weird and I was only 90% sure.

Approaches and Considerations in Mild Cognitive Impairment Due to Alzheimer Experts discuss the importance of early diagnosis in Alzheimer disease, and discuss the safety and efficacy of newer treatment options for mild cognitive impairment.

Check this conversation out on Neurology Live.

www.neurologylive.com/peers-perspe...

An unblinded story is a type of data.

The basis of informed consent is falsifying medical records?

Anti-vaxx ate my face party?

Building an Infrastructure to Administer Amyloid-Targeting Treatments With the introduction of amyloid-targeting therapies, clinicians face a paradigm shift, requiring new clinical systems, interdisciplinary teams, and exper…

How to implement anti-amyloid therapies lecanemab or donanemab:

practicalneurology.com/diseases-dia...

Lilly Gets FDA Label Update for Alzheimer’s Drug To Mitigate Safety Concerns The FDA will allow a new dosing schedule for Eli Lilly’s Alzheimer’s drug Kisunla that could lessen a known side effect of the monoclonal antibody drug class that has led to several deaths.

New titration of donanemab is approved. Not aware of anyone who use the previous titration, but good to see this.

www.biospace.com/policy/lilly...

Philly.

Radiologists are fast learners in this regard. Especially when you write "on anti-amyloid therapy, eval for ARIA before dose 5" on the order.

That said, I've had to call after baseline MRIs showing "a few" microhemes. Like dude, this is 2025, where do you think we are, England?

I also left Twitter. So I'm just as likely to come across an NPR article here, perhaps more so.