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Melike Eren

@neurowithmelike.bsky.social

MSc. Neuroscience &MSc.Physiotherapy| Just a researcher, microglia lover |I hope to become a PhD student in neuroscience | Neuroscience, Anatomy & Exercise Physiology

1,271 Followers  |  7,625 Following  |  288 Posts  |  Joined: 04.04.2025
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Posts by Melike Eren (@neurowithmelike.bsky.social)

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Honoring Women in Neuroscience In honor of Women’s History Month, celebrate the many contributions women have made to the field of neuroscience.

In honor of #WomensHistoryMonth, celebrate the many contributions women have made to the field of neuroscience. vist.ly/4u9sh

09.03.2026 14:20 β€” πŸ‘ 3    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0

Efficacy of BodyMirror Clinical MS Multimodal Game-Based Digital Therapeutic for Remote Monitoring and Neurorehabilitation in Multiple Sclerosis: Protocol for a Multisite Randomised Controlled Trial #NeuroDegeneration πŸ§ͺ🧠
https://www.medrxiv.org/content/10.64898/2026.03.06.26347719v1

07.03.2026 17:01 β€” πŸ‘ 1    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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Biphasic inflammation control by fibroblasts enables spinal cord regeneration in zebrafish Fibrosis and persistent inflammation are interconnected processes that inhibit axon regeneration in the mammalian central nervous system (CNS). Here, …

New paper from the lab is out in Cell Reports:

www.sciencedirect.com/science/arti...

23.10.2025 07:45 β€” πŸ‘ 15    πŸ” 3    πŸ’¬ 1    πŸ“Œ 0
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Brain Growth Patterns Predict 2-Year Neurodevelopment bioengineer.org/brain-growth...
Growth of fetal brain with long-term neurodevelopmental validation provides insights into in utero brain maturation and their predictive relationship with postnatal neurological function. doi.org/10.1038/s414...

26.02.2026 14:48 β€” πŸ‘ 5    πŸ” 4    πŸ’¬ 0    πŸ“Œ 0
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Mitochondria contact lipid droplets through the mitochondrial import complex binding to lipid metabolism enzyme Ayr1 - Nature Cell Biology Heinen et al. show that the mitochondrial import complex recruits lipid droplets to the mitochondrial outer membrane. The mitochondrial import complex binds to the lipid metabolism enzyme Ayr1 and con...

Mitochondria contact lipid droplets through the mitochondrial import complex binding to lipid metabolism enzyme Ayr1
πŸ‘‰https://rdcu.be/e7dRa
bit.ly/4baJZAO

06.03.2026 15:55 β€” πŸ‘ 13    πŸ” 6    πŸ’¬ 0    πŸ“Œ 1
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Endoplasmic reticulum–mitochondria contact sites are signalling hubs connecting nutrient sensing and GLP-1 secretion in L cells of the mouse gut: from physiology to obesity and type 2 diabetes - Diabe... Aims/hypothesis Postprandial glucagon-like peptide-1 (GLP-1) secretion by enteroendocrine L cells of the gut plays an important role in glucose homeostasis, thus representing a therapeutic option of e...

ER–mitochondria calcium coupling is essential for glucose-induced GLP-1 secretion in L cells @diabetologiajnl.bsky.social
link.springer.com/article/10.1...

08.03.2026 12:23 β€” πŸ‘ 11    πŸ” 3    πŸ’¬ 0    πŸ“Œ 0
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An extracellular vesicle-mediated mitochondrial transfer network critical for testosterone synthesis - Nature Cell Biology Xia, Zhang, Peng, Chen et al. find that Leydig cells and macrophages show bidirectional mitochondrial transfer through extracellular vesicles, ensuring Leydig cells have functional mitochondria. The e...

β˜•Xia, Zhang, Peng, Chen et al. find that #Leydig cells and macrophages show bidirectional mitochondrial transfer through #ExtracellularVesicles, ensuring Leydig cells have functional #mitochondria. The exchange is needed for testosterone production.
bit.ly/40US4Vy

09.03.2026 14:52 β€” πŸ‘ 8    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0
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Anarcha Westcott mother of gynecology 17 yr old enslaved underwent 30 operations without anesthesia for a vesicovaginal fistula James Marion Sim was the racist man who performed these surgeries on her and is denoted as the father of Gynecology. strength, grit, and bravery survived those procedures.

06.03.2025 12:23 β€” πŸ‘ 2    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0

who cannot afford to dissent, who cannot afford to be seen their silence is political too. To pretend otherwise is not neutrality. It is complicity. I will not perform apolitical comfort for anyone's peace of mind. My existence, like yours, is already a political act. I'd rather be honest about it.

09.03.2026 14:17 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

The era we happen to live in. Our gender. The profession we chose or the one that chose us out of necessity. Every waking moment of the working class which is to say, most of us is saturated with politics. The worker who cannot afford to rest,

09.03.2026 14:17 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

a mood board than a reality. But sure let's protect it. I find it deeply unethical to perform a version of myself I'm not to mask my thoughts, to shrink my convictions for the sake of palatability.
Everything is political. The country we were born into.

09.03.2026 14:17 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

Sometimes I receive well-meaning warnings from professors including ones I genuinely adore" be careful, talking too much about politics is dangerous for your career." My career?How adorable. I haven't even been accepted into a PhD program yet, so my "career" is currently more of

09.03.2026 14:17 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

Temporally-precise sensory encoding of predicted content, entraining motor oscillations to derive time. @akalt.bsky.social's first study out @currentbiology.bsky.social, testing parts of this idea (tinyurl.com/TiCSKaltenma...). Huge thanks @leverhulme.ac.uk ac.uk @erc.europa.eu, great work Aaron!

09.03.2026 10:19 β€” πŸ‘ 27    πŸ” 9    πŸ’¬ 0    πŸ“Œ 0
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She didn’t just teach physics. She built a lab where science became real. πŸ”­
Women’s History Month reminds us how many innovators never got the chances they deserved.
Sarah Frances Whiting created one of the earliest hands‑on physics programs for women in the US. 1/2 🧡

09.03.2026 13:40 β€” πŸ‘ 1    πŸ” 1    πŸ’¬ 1    πŸ“Œ 0

and their mothers' mothers before them. Nobody handed us our rights, and nobody is going to. Rights are not given. Rights are taken. We are not a movement that began yesterday. We are not a movement that will end tomorrow. We are 180 years of fury, resistance, and refusal to disappear.

09.03.2026 13:00 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

founded in 1923, stands as one of the first feminist political parties in human history. So let's be clear: the women of this land never waited for a savior. They did not ask. They did not beg. They organized, they fought, and they took what was theirs, on the shoulders of their mothers,

09.03.2026 13:00 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

Our first graduates walked across that stage between 1895 and 1917, interrupted only by the chaos of war, not by doubt, not by permission. Women here won the right to vote in 1930 and 1934, ahead of many so-called "advanced" nations. The Women's People's Party -KadΔ±n Halk Firkasi

09.03.2026 13:00 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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And countless banners I cannot translate. The history of feminism in our country and region spans 180 years, and we wrote every chapter ourselves. Turkey admitted women to universities before most of the world, training them in medicine, mathematics, philosophy, and literature.

09.03.2026 13:00 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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1-The first signs of spring (a symbol of spring in Turkish culture) have appeared, now it's patriarchy's turn
2-Oh life, I will either live you freely or consider you unlived
3-If the sun shines only for the bourgeoisie, then extinguish it too
4-Poverty has no homeland, struggle has no race

09.03.2026 13:00 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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March 8th feminist night march from Turkey.
1-If you despair, remember this crowd.
2-Keep your anger alive, hold your head high, and hold your sister's hand tightly.
4-There's fragile masculinity at dinner today.

09.03.2026 13:00 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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Targeting amyloid-Ξ² pathology by chimeric antigen receptor astrocyte (CAR-A) therapy Alzheimer’s disease (AD) is the leading cause of dementia and is characterized by progressive amyloid accumulation followed by tau-mediated neurodegeneration. Despite advances in anti-amyloid immunoth...

Targeting amyloid-Ξ² pathology by chimeric antigen receptor astrocyte (CAR-A) therapy

www.science.org/doi/10.1126/...

06.03.2026 20:07 β€” πŸ‘ 1    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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Astrocyte CB1 receptors drive blood-brain barrier disruption in central nervous system inflammatory disease - Journal of Neuroinflammation Journal of Neuroinflammation - Reactive astrocytes shape central nervous system (CNS) inflammation and participate in myelin damage and repair mechanisms in multiple sclerosis (MS). Through the...

Astrocyte CB1 receptors drive blood-brain barrier disruption in central nervous system inflammatory disease- link.springer.com/article/10.1... #neuroskyence πŸ§ͺ🌎

03.02.2026 21:18 β€” πŸ‘ 12    πŸ” 7    πŸ’¬ 0    πŸ“Œ 0
Striatal neuroinflammation causes excessive goal-directed action control in a region specific manner.

Striatal neuroinflammation causes excessive goal-directed action control in a region specific manner.

Brain inflammation may be driving compulsive behavior

Could it be less about β€œbad habits” and more about an inflamed brain working too hard?

Dorsomedial striatal neuroinflammation causes excessive goal-directed action control by disrupting astrocyte function πŸ§ͺ
www.nature.com/articles/s41...

23.02.2026 15:02 β€” πŸ‘ 13    πŸ” 3    πŸ’¬ 0    πŸ“Œ 1
Collaborating teams from @Department of Physiology, Anatomy and Genetics and @Department of Chemistry at University of Oxford engineered 3D microfluidic constructs containing human neuronal progenitor cells (NPCs) cultured either alone or together with mouse astrocytes. 
The results were striking. Compared to NPCs alone, co-cultures exhibited:
Enhanced neuronal maturation
Increased cell viability and density
Reduced lesion size after implantation
Greater axonal outgrowth
Improved astrocyte coupling to blood vessels within the graft.
High-resolution deconvolved microscopy confirmed the presence of synapses within the implants, while optogenetic experiments demonstrated functional connections between host brain tissue and the transplanted constructs.
Both NPC-only and co-culture grafts increased astrocyte size, but co-cultures demonstrated superior structural and functional outcomes overall, underscoring the importance of astrocyte–neuron interactions from the outset.
https://advanced.onlinelibrary.wiley.com/.../advs.202507423 
The research was done with support from the Oxford Martin School- https://www.oxfordmartin.ox.ac.uk/brain-repair Oxford Martin School
More details: https://www.dpag.ox.ac.uk/.../study-reveals-unexpected...

Collaborating teams from @Department of Physiology, Anatomy and Genetics and @Department of Chemistry at University of Oxford engineered 3D microfluidic constructs containing human neuronal progenitor cells (NPCs) cultured either alone or together with mouse astrocytes. The results were striking. Compared to NPCs alone, co-cultures exhibited: Enhanced neuronal maturation Increased cell viability and density Reduced lesion size after implantation Greater axonal outgrowth Improved astrocyte coupling to blood vessels within the graft. High-resolution deconvolved microscopy confirmed the presence of synapses within the implants, while optogenetic experiments demonstrated functional connections between host brain tissue and the transplanted constructs. Both NPC-only and co-culture grafts increased astrocyte size, but co-cultures demonstrated superior structural and functional outcomes overall, underscoring the importance of astrocyte–neuron interactions from the outset. https://advanced.onlinelibrary.wiley.com/.../advs.202507423 The research was done with support from the Oxford Martin School- https://www.oxfordmartin.ox.ac.uk/brain-repair Oxford Martin School More details: https://www.dpag.ox.ac.uk/.../study-reveals-unexpected...

Collaborating teams from @Department of Physiology, Anatomy and Genetics and @Department of Chemistry at University of Oxford engineered 3D microfluidic constructs containing human neuronal progenitor cells (NPCs) cultured either alone or together with mouse astrocytes. 
The results were striking. Compared to NPCs alone, co-cultures exhibited:
Enhanced neuronal maturation
Increased cell viability and density
Reduced lesion size after implantation
Greater axonal outgrowth
Improved astrocyte coupling to blood vessels within the graft.
High-resolution deconvolved microscopy confirmed the presence of synapses within the implants, while optogenetic experiments demonstrated functional connections between host brain tissue and the transplanted constructs.
Both NPC-only and co-culture grafts increased astrocyte size, but co-cultures demonstrated superior structural and functional outcomes overall, underscoring the importance of astrocyte–neuron interactions from the outset.
https://advanced.onlinelibrary.wiley.com/.../advs.202507423 
The research was done with support from the Oxford Martin School- https://www.oxfordmartin.ox.ac.uk/brain-repair Oxford Martin School
More details: https://www.dpag.ox.ac.uk/.../study-reveals-unexpected...

Collaborating teams from @Department of Physiology, Anatomy and Genetics and @Department of Chemistry at University of Oxford engineered 3D microfluidic constructs containing human neuronal progenitor cells (NPCs) cultured either alone or together with mouse astrocytes. The results were striking. Compared to NPCs alone, co-cultures exhibited: Enhanced neuronal maturation Increased cell viability and density Reduced lesion size after implantation Greater axonal outgrowth Improved astrocyte coupling to blood vessels within the graft. High-resolution deconvolved microscopy confirmed the presence of synapses within the implants, while optogenetic experiments demonstrated functional connections between host brain tissue and the transplanted constructs. Both NPC-only and co-culture grafts increased astrocyte size, but co-cultures demonstrated superior structural and functional outcomes overall, underscoring the importance of astrocyte–neuron interactions from the outset. https://advanced.onlinelibrary.wiley.com/.../advs.202507423 The research was done with support from the Oxford Martin School- https://www.oxfordmartin.ox.ac.uk/brain-repair Oxford Martin School More details: https://www.dpag.ox.ac.uk/.../study-reveals-unexpected...

Teams from DPAG and Chemistry at @ox.ac.uk engineered 3D constructs containing human neuronal progenitor cells cultured either alone or together with mouse astrocytes.
Co-cultures performed much better advanced.onlinelibrary.wiley.com/doi/10.1002/...
@martinschool.bsky.social

01.03.2026 12:27 β€” πŸ‘ 7    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0

and historical artifacts. Of course, in the meantime, our children are being killed, women are being raped, sold, and organs are being trafficked. But come on, aren't we exaggerating this? Oh, we Middle Easterners are so ignorant, blah blah blah.

09.03.2026 00:31 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

an ancient civilization. Or, for example, people want to use the oil, natural gas, and gold that comes out of their own countries. What a lack of civilization! The people of the Middle East and Africa are literally defending themselves. What rights do they have? Freedom for gas, gold, oil,

09.03.2026 00:31 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

The same thing exists in Turkey,because we plant trees wherever we find space and have an irrigation system called β€œarΔ±k.” Oh my God,we are planting trees again out of ignorance; we need to get rid of this.This is what happens when stupidity and cultural ignorance are used as military force against

09.03.2026 00:29 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

The sewer system is not what caused the fire to spread through the city. These are water channels (joob) designed to water trees, a tradition based on Iran's ancient water management and cooling systems.

09.03.2026 00:29 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

Or were we never seen as human beings in the first place? I don't know, but at the very least, our children deserve to be treated as children, and our patients deserve respect as patients.

08.03.2026 21:14 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

Which country will be next when they complete the second, third, fifth, twenty-fifth... genocide? When will they finally say, β€œEnough, yes, enough is enough”?I'm very curious: when exactly did we and our neighbors stop being seen as human beings?

08.03.2026 21:14 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0