Melike Eren

Do Mitochondria Drive Mind-Body Processes? An Introduction to the MiSBIE Study

martinpicard.substack.com/p/researchin...

Global remapping of the sensory homunculus emerges early in childhood development - Nature Communications Children born without a hand show early, widespread changes in brain maps, with body parts shifting across the homunculus. Adaptive behaviours explain individual differences but cannot override this e...

We're thrilled to announce that our new research article, "Global remapping of the sensory homunculus emerges early in childhood development”, has just been published in Nature Communications (www.nature.com/articles/s41...) with @dorothycowie.bsky.social and Matej Hoffman.

Claude Code 27: Research and Publishing Are Now Two Different Things Some Claude Code fan fiction about the economics of publishing with AI agents set in the very near future

This post really put together the pieces in a way that floored me. Everything is about to change and we have to confront that reality causalinf.substack.com/p/claude-cod...

‘I
know a sad little fairy
who lives in an ocean
and plays her heart out softly, softly
on a pennywhistle
a sad little fairy
who dies with a kiss at night
and is born with a kiss at dawn’

Another Birth by Forough Farrokhzad

A Spatial Cell Atlas of the Spinal Cord Reveals New Clues to Chronic Pain | HHMI A team led by HHMI Hanna Gray Fellow Shan Meltzer has created a detailed, cell-by-cell map of the spinal cord that offers a new framework for understanding chronic pain and provides a powerful new res...

www.hhmi.org/news/spinal-...

Cognitive control networks in human and macaque
doi.org/10.64898/202...
#neuroscience

This study investigates the mechanisms behind exercise's protective effects in Alzheimer's disease (AD). Ps; I want to pursue a doctorate because I observed this effect in the clinic and want to learn more about it at a more molecular level, as in this study.
www.nature.com/articles/s43...

🧠 New paper from UP NExT flips the script on brain implants! Microglia (brain's immune cells) aren't just causing inflammation & scarring around electrodes, they actively monitor & interact with stressed neurons during low-freq stim via
Live 2-photon imaging
#Neuroscience #BCI

A new preprint introduces aDISCO, a DISCO-based clearing approach that makes whole archival FFPE human tissues transparent and antibody-compatible, enabling true 3D light-sheet histology across brain & multiple organs at cellular resolution. Aguzzi & Helmchen teams.
www.biorxiv.org/content/10.1...

The complexity of interpreting TSPO PET neuroimaging in first-episode psychosis

New scientific commentary by Agnieszka Kalinowski & Lawrence Steinman shorturl.at/dqEO5

Soni argues that modern seizure classifications change too often, confusing clinicians and pts. Contrasting them with the stable, descriptive approaches of Hippocrates, Galen and Ibn Sina, she calls for simpler, enduring language to improve epilepsy care. shorturl.at/FKKeG

For those who are interested, I worked on neuroimmunological mechanisms in Parkinson's disease during my master's degree, using cell cultures and animal experiments. I have experience as a molecular lab, animal experiment and anatomy lab assistantship. Thank you.

I'm almost there, I have good research ideas, but I'll cry until I get accepted and start doing research. Vallahi, it had crossed my mind too.

miR-378a-overexpressing myotubes to AD mice alleviated cognitive impairment. The study defines a novel exercise → muscle → brain communication axis. SKM-EVs are proposed as a potential exercise-mimicking therapeutic strategy for AD offering a promising avenue for patients unable to exercise.

Key Molecule: miR-378a-3p The critical cargo within the vesicles was identified as miR-378a-3p, a microRNA that regulates lipid metabolism in microglia by targeting the protein p110α. Therapeutic Potential Administering vesicles derived from

Amyloid Plaque Clearance SKM-EVs polarize microglia into a disease-associated phenotype, enabling more effective clearance of amyloid-beta plaques the hallmark pathology of AD.

Exercise → Muscle-Derived Vesicles Swimming exercise promotes secretion of skeletal muscle-derived extracellular vesicles (SKM-EVs), which travel through the bloodstream to the brain. Summary
This study investigates the mechanisms behind exercise's protective effects in Alzheimer's disease (AD).

This study investigates the mechanisms behind exercise's protective effects in Alzheimer's disease (AD). Ps; I want to pursue a doctorate because I observed this effect in the clinic and want to learn more about it at a more molecular level, as in this study.
www.nature.com/articles/s43...

JCI - Disruption of CSF-1 receptor-mediated metal ion homeostasis in the murine brain promotes neurodegenerative disease www.jci.org/articles/vie...

In NEW STUDY, researchers Nalini Rao, et al. @feinberg.northwestern.edu pinpointed when & where toxic proteins accumulate w/in brains of #Alzheimers patients, & discovered an @fda.gov approved drug that can stop accumulation process before it begins. @science.org 👉 www.science.org/doi/10.1126/...

More Philly-area students are majoring in neuroscience, with some wanting to find cures for Alzheimer’s and Parkinson’s In 2008, 110 colleges nationally offered neuroscience majors; now, it’s about 330, said Raddy Ramos, associate professor in the Department of Biomedical Sciences at New York Institute of Technology.

World on fire, but more peeps interested in #neuroscience 🧪🧠 so that’s nice (gift article) share.inquirer.com/3GeHKx @pennmindcore.bsky.social @laurabeen.bsky.social

📢 New webinar coming soon 📢 
Tara DeSilva from Cleveland Clinic will be our next speaker on March 3rd. Check all the information in the flyer and add it to your calendar! 🧬🧠

Astrocyte Cafe - Seminars & 2026 Conference Join the international astrocyte research community. Monthly seminars and the 2026 Pamplona Conference.

Registrations and abstract submissions for #AstrocyteCafe2026 are now OPEN!!!

Spread the word 🤩
We hope to see many of you on June 3-5 in Pamplona!!!

Thanks Kernel Science, for our brand new website and for helping organize this conference!
👇👇👇👇

astrocytecafe.com#/conference-...

Le French Glial Cell Club participe à la Semaine du Cerveau avec France Alzheimer !

📅 Rendez-vous en ligne pour un live immersif
🕘 Lundi 16 mars à 19 h
📍 Sur YouTube et Twitch

Découvrez les avancées de la recherche, le rôle central des cellules gliales et posez vos questions à nos experts.

Blood cells circulating in the head of a fruit fly.

Face of a fruit fly that helped #HHMIInvestigator Amita Sehgal and team uncover how sleep acts as a critical "cellular housekeeper," keeping our neurons healthy (and so much more) — findings that could drive a better understanding of neurodegenerative diseases like Alzheimer’s: bit.ly/3ZKNFnK.

Our Brains, Our Selves: What a Neurologist’s Patients Taught Him About the Brain - an evening with Masud Husain | Events at Waterstones Bookshops | Waterstones Events at Waterstones get you closer to the books and authors you admire most. Find information and tickets about Our Brains, Our Selves: What a Neurologist’s Patients Taught Him About the Brain - an...

Did you enjoy the talk from Professor Masud Husain at #AAICNeuro - You can meet him in-person at the 'Our Brains, Our Selves: What a Neurologist’s Patients Taught Him About the Brain' event at Waterstones on Gower Street this week.

www.waterstones.com/events/our-b...

As body-augmenting technologies become more common, it is important to understand how the brain decides what counts as "the body", and how that changes over time.

My first postdoc paper 🦾 now out in @elife.bsky.social 👇

After 5 years of developing, a new preprint from the lab - introducing our workflow for comparative insect connectomics, aimed at democratizing connectomics. @erc.europa.eu @lundvision.bsky.social @biologylu.bsky.social Read it here: www.biorxiv.org/content/10.6...

These reviews on neural manifolds are super relevant to today’s world of large-scale population recordings. How do we link circuits, population geometry, dynamics, and function?

“A neural manifold view of the brain” from Perich, Narain, and Gallego 2025

www.nature.com/articles/s41...

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Experimenting with an AI-curated neuroscience feed. It scans the entire firehose in real time, prefilters for neuro/cogsci keywords, then a local LLM scores each post for scientific substance. A ranking algorithm blends that quality score with engagement to surface the best discussion. Try it out!