ISACB

Differential effects of demographics and risk factors on the nonlinear orthotropic mechanical properties of human femoropopliteal arteries - Biomechanics and Modeling in Mechanobiology Understanding how demographics and risk factors differentially affect the nonlinear orthotropic mechanical properties of human femoropopliteal arteries (FPAs) is critical for improving computational m...

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Differential effects of demographics and risk factors on the nonlinear orthotropic mechanical properties of human femoropopliteal arteries

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Suitability of Endovascular Materials for Physician-Modified Fenestrated Endografts in Urgent Juxtarenal and Pararenal Aortic Pathologies

www.mdpi.com/2077-0383/14...

CD137 Signaling Modulates Vein Graft Atherosclerosis by Driving T-Cell Activation and Regulating Intraplaque Angiogenesis:

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CD137 Signaling Modulates Vein Graft Atherosclerosis by Driving T-Cell Activation and Regulating Intraplaque Angiogenesis

www.jacc.org/doi/10.1016/...

Integrin’g Endocytosis and Vascular Calcification in Chronic Kidney Disease | Circulation Research

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Integrin'g Endocytosis and Vascular Calcification in Chronic Kidney Disease

www.ahajournals.org/doi/10.1161/...

Inverse finite element identification of murine aortic material properties: in vivo and ex vivo comparisons Inverse finite element (FE) models can non-invasively estimate aortic mechanical properties from in vivo imaging. However, few studies have compared model predictions with direct mechanical charact...

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Inverse finite element identification of murine aortic material properties: in vivo and ex vivo comparisons

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Toroidal Indentation for Measuring Cell and Tissue Mechanical Anisotropy Indentation-based mechanical tests are advantageous for measuring tissue and cell stiffness due to their simplicity and ability to probe samples non-d…

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Toroidal Indentation for Measuring Cell and Tissue Mechanical Anisotropy

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Novel design of 3D printed tumbling microrobots for in vivo targeted drug delivery This paper presents innovative designs for 3D-printed tumbling microrobots, specifically engineered for targeted in vivo drug deliv- ery applications.…

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Novel design of 3D printed tumbling microrobots for in vivo tar- geted drug delivery

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Cellular and Matrix Organisation of the Human Aortic Valve Interleaflet Triangles

www.mdpi.com/2079-7737/14...

Evaluation of in situ tissue-engineered arteriovenous grafts suitable for cannulation in a large animal model - Communications Materials Vascular access for hemodialysis is often compromised by synthetic grafts that lack self-healing capabilities. Here, electrospun polycarbonate-bis urea grafts, reinforced with 3D-printed polycaprolact...

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Evaluation of in situ tissue-engineered arteriovenous grafts suitable for cannulation in a large animal model

www.nature.com/articles/s43...

Modulating the platelet-mediated innate foreign body response to affect in situ vascular tissue engineering outcomes - npj Regenerative Medicine npj Regenerative Medicine - Modulating the platelet-mediated innate foreign body response to affect in situ vascular tissue engineering outcomes

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Modulating the platelet-mediated innate foreign body response to affect in situ vascular tissue engineering outcomes

www.nature.com/articles/s41...

Computationally-informed point of departure evaluation for proarrhythmic cardiotoxicity assessment using 3D engineered cardiac microtissues from human iPSC-derived cardiomyocytes Abstract. Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) are a promising new approach for in vitro proarrhythmic cardiotoxicity ass

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Computationally-informed point of departure evaluation for proarrhythmic cardiotoxicity assessment using 3D engineered cardiac microtissues from human iPSC-derived cardiomyocytes

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Autologous and synthetic vascular grafts trigger different host responses in the anastomotic regions and in the perivascular adipose tissue during the early healing phase Interactions between tissue and material post-implantation significantly impact the long-term behavior of vascular prostheses. Autologous materials ar…

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Autologous and synthetic vascular grafts trigger different host responses in the anastomotic regions and in the perivascular adipose tissue during the early healing phase

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Combined dietary omega-3 and omega-6 fatty acids protect against hyperglycemia-associated retinopathy in neonatal mice Retinopathy of prematurity (ROP) with early vessel loss (Phase I) followed by uncontrolled vessel growth (Phase II) causes visual impairment in premat…

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Combined dietary omega-3 and omega-6 fatty acids protect against hyperglycemia-associated retinopathy in neonatal mice

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In vitro model assesses the susceptibility of polymeric scaffolds for material-driven heart valve regeneration to calcification - In vitro models Purpose Material driven in situ heart valve tissue engineering (HVTE) prospects an alternative to non-living replacements. HVTE exploits bioresorbable (synthetic) scaffolds that guide neo-tissue forma...

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In vitro model assesses the susceptibility of polymeric scaffolds for material-driven heart valve regeneration to calcification

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Evaluation of the Bioinductive Effects of a Novel Antibiotic Eluting Cardiac Implantable Electronic Device Envelope

www.mdpi.com/2079-4983/16...

Frontiers | Temporal dynamics of gene and protein signatures following volumetric muscle loss IntroductionVolumetric muscle loss (VML) is characterized by permanent tissue impairment resulting from critically-sized muscle loss. We performed time-serie...

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Temporal dynamics of gene and protein signatures following volumetric muscle loss

www.frontiersin.org/journals/cel...

Frontiers | CXCR5 engineered human and murine Tregs for targeted suppression in secondary and tertiary lymphoid organs IntroductionSecondary and tertiary lymphoid structures are a critical target of suppression in many autoimmune disorders, protein replacement therapies, and ...

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CXCR5 engineered human and murine Tregs for targeted suppression in secondary and tertiary lymphoid organs

www.frontiersin.org/journals/imm...

Glycolysis hijacked: a novel pathogenic role of lipoprotein(a) in valve disease This editorial refers to ‘Fuelling stenosis: the integral role of PFKFB3-mediated glycolysis in Lp(a)-induced valve inflammation’, by M. Peletier et al. ht

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Glycolysis hijacked: a novel pathogenic role of lipoprotein(a) in valve disease

academic.oup.com/ehjopen/arti...

Hypotaurine Reduces Glucose‐Mediated Vascular Calcification Aim Vascular calcification (VC), a characteristic feature of peripheral artery disease in patients with diabetes and chronic kidney disease, has been associated with poor prognosis. We hypothesize t.....

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Hypotaurine Reduces Glucose-Mediated Vascular Calcification

onlinelibrary.wiley.com/doi/10.1111/...

Biocompatibility of decellularized spinach leaves - npj Biomedical Innovations npj Biomedical Innovations - Biocompatibility of decellularized spinach leaves

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Biocompatibility of decellularized spinach leaves

www.nature.com/articles/s44...

ISACB is searching for candidates to serve as new members of our Committees and Executive Council!

We welcome applications from members at all career stages who wish to contribute to the growth of our society.

Please apply now via: forms.gle/2E1eyPznNJXn...

Save-the-Date for #ISACB2026 in #Miami!

We are excited to announce that the next Biennial @appliedcvb.bsky.social ISACB meeting will be held in beautiful #Miami from November 11-14, 2026.

Be sure to save the date in your calendar! More details coming soon.

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Monocyte/Macrophages: Unexpected Allies in the Fight Against Arterial Thrombosis?

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Nanosilicates promote angiogenesis through activation of ROS-mediated WNT/β-catenin pathway Nanosilicates enhance scaffold vascularization for tissue regeneration.

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Nanosilicates promote angiogenesis through activation of ROS-mediated WNT/β-catenin pathway

www.science.org/doi/10.1126/...

Microscope-assisted, rodent whole heart perfusion fixation for histological characterization of myocardium remodeling Investigating mechanisms of heart disease, its progression, and developing therapeutics that target cardiac remodeling often requires translational mo…

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Microscope-assisted, rodent whole heart perfusion fixation for histological characterization of myocardium remodeling

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Physiological Response of Tissue-Engineered Vascular Grafts to Vasoactive Agents in an Ovine Model | Tissue Engineering Part C: Methods Tissue-engineered vascular grafts (TEVGs) are emerging as promising alternatives to synthetic grafts, particularly in pediatric cardiovascular surgery. While TEVGs have demonstrated growth potential, ...

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Physiological Response of Tissue-Engineered Vascular Grafts to Vasoactive Agents in an Ovine Model

www.liebertpub.com/doi/10.1089/...

Human Bone‐Derived Endothelial Cells Mediate Bone Regeneration via Distinct Expression of KIT Ligand Bone-specific endothelial cells (b-ECs) uniquely express KITLG, which recruits c-Kit+/CD34+ hematopoietic progenitors (HPCs) to the osteovascular niche, initiating a cascade that culminates in the os....

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Human Bone-Derived Endothelial Cells Mediate Bone Regeneration via Distinct Expression of KIT Ligand

advanced.onlinelibrary.wiley.com/doi/10.1002/...

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Considerations on the Development of Therapeutics in Vascular Calcification

www.mdpi.com/2308-3425/12...

Progress on Incorporating Sex as a Biological Variable in Cardiovascular Research | American Journal of Physiology-Heart and Circulatory Physiology | American Physiological Society

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Progress on Incorporating Sex as a Biological Variable in Cardiovascular Research

journals.physiology.org/doi/abs/10.1...

Medial arterial calcification in ageing and disease: current evidence and knowledge gaps Abstract. Medial arterial calcification (MAC) characterizes human arterial ageing, potentially remaining clinically silent for decades. However, in suscept

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Medial arterial calcification in ageing and disease: current evidence and knowledge gaps

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