Dengue virus susceptibility in Aedes aegypti linked to natural cytochrome P450 variants The mosquito Aedes aegypti is the primary vector for dengue virus (DENV), which infects millions of people annually. Variability in DENV susceptibility among wild Ae. aegypti populations is governed b...

Now with link: www.biorxiv.org/content/10.1...

28.02.2025 11:57 — 👍 0    🔁 0    💬 0    📌 0

Intriguing preprint by @merklinglab.bsky.social and @lambrechtslab.bsky.social Cytochrome P450 as an antiviral factor against dengue in mosquitoes.

28.02.2025 11:56 — 👍 2    🔁 0    💬 2    📌 1

Phylogenetic map of wildlife trade; graphs showing overlap with other traits like synanthropy; path analysis showing impact on zoonotic host status

Huge analysis out as a preprint today! For every 9 years an animal spends in the wildlife trade, it shares an additional pathogen with humans. Clear long-term impacts based on 40 years of global trade data 🧪😷 biorxiv.org/content/earl...

10.02.2025 13:39 — 👍 155    🔁 54    💬 3    📌 6

The CNRS research department “Insects Models of Innate Immunity” invites applications for a group leader position. Applicants must have a strong record of scientific accomplishments in Drosophila genetics, innate immunity/host-pathogen interactions, or insect physiology. We are looking for candidates who will bring new lines of research to the department (evolution, regulation of gene expression, metabolism, bioinformatics, etc…) and willing to work collaboratively with existing groups in the NetRNA LabEx network (https://labex-netrna.cnrs.fr/presentation/netrnateams/). The department “Insects Models of Innate Immunity” performs cutting edge basic research on insect-pathogen interactions, focusing on the fruit-fly Drosophila as well as vector mosquitoes Anopheles and Aedes (https://ibmc.cnrs.fr/en/laboratoire/m3i/). The department is part of the Institute of Molecular and Cellular Biology (IBMC), located at the heart of the University of Strasbourg campus in France. The IBMC provides a world-class research environment, equipped with cutting-edge facilities for proteomics, genomics, advanced cell imaging and a dedicated insectarium for infectiology studies, including BSL3 containment. Our department participates in the NetRNA consortium, which offers a start-up package of 450k€ covering salary and research support for 3-5 years. Applicants should submit before March 31st , 2025, a curriculum vitae, a summary of research accomplishments (1-2 pages), a summary of future research plans (1-2 pages) and contact information for three professional references. Applications in the form of a single pdf document, or any question regarding the position, should be sent to m3i-sec@ibmc-cnrs.unistra.fr.

Great looking group leader position at CNRS Strasbourg on host-pathogen interactions in insects

10.01.2025 10:56 — 👍 6    🔁 13    💬 0    📌 0