Chase Bolt

Amazon/MGM removes all guns from James Bond digital posters on Prime 007 is without his Walther PPK on the latest digital posters featured on Prime Video for the James Bond series.

The enshitification continues. I'm not even a Conservative, I just think it is fucking stupid to remove a gun from a picture when the 27 movies are just two hours of guns. There is a person in this world that gets paid - probably a shit ton of money - to make these meaningless decisions.

Craft Breweries Struggle as Sales and Appetites Wane

Here is a clue, make anything other than a fucking IPA.

Thank you Marian!

There is only #babyshark

Thanks Olga!

Thanks Dario!

Yes they do!

Thank you Neil!

Co-option of an ancestral cloacal regulatory landscape during digit evolution - Nature The regulatory landscape controlling Hoxd gene expression in tetrapod digit development was probably co-opted from a pre-existing cloacal regulatory mechanism, as evidenced by the effects of gene...

Link to the original work (dummy).
www.nature.com/articles/s41...

How Did Hands Evolve? The Answer Is Behind You.

Our work exploring a new explanation for the regulation of Hoxd genes and the #fin-to-limb transition. 🧪

It was an absolute joy working on this w/ @aurhin.bsky.social and @homeobox.bsky.social @denisduboule.bsky.social @neilshubin.bsky.social

#evo-devo #InHoxWeTrust

The precarious future of consumer genetic privacy Congress and other lawmakers must act to robustly protect direct-to-consumer genetic data and biospecimens into the future

There is a lot of concern about leaked genetic data, but what I wonder is, can a "reputable" legal entity like a health insurance company use this information? Or the government? Wouldn't the chain of custody be unreliable? #genetic #privacy

sequence that dude

Merry Crispus!

Join this year's CSH Asia Systems Biology of Gene Regulation & Genome Editing meeting in beautiful Suzhou, China, Oct 20-24. Let's bring the international communities together! Abstract deadline Sept 19! Infos and registration at csh-asia.org?content/2767. Please repost!

The end of the genetic paradigm of cancer Genome sequencing results and single-cell transcriptomics continue to produce findings that challenge the idea that cancer is purely a ‘genetic disease’. This Essay delves into cancer omics data that ...

"the quest for drug targets have meanwhile reduced much of cancer research from a scholarly biological discipline to a transactional operation concerned more with cataloguing molecular alterations and finding associations, than with understanding fundamental principles using formal theory." Agreed.

Conservative influencer Charlie Kirk shot dead at Utah event Kirk, an activist and the founder of conservative student group Turning Point USA, played a key role in driving youth support for Trump in November.

Charlie Kirk is dead by assassination. This political violence needs to stop. Things will only continue to get worse. I didn't like him but no one should be killed for their beliefs and speaking them aloud.

Drivers recruit pioneer factors that then "hop" to near-3D contacts to spread active chromatin context, producing a stable active landscape.

Enhancers mediate euchromatin hopping at chromatin contact points Enhancer-mediated gene activation involves the recruitment of chromatin modifiers and RNA polymerase to target promoters, but it is unknown if enhancers influence chromatin beyond their target genes. ...

Euchromatin hopping explains how some enhancers seem to initiate the formation of active regulatory landscapes, and why some/many enhancer deletions don't affect transcription quantity; there are driver and passenger enhancers.
#chromatin #enhancers #generegulation

As a former #evo-devo academic that moved to industry, I can say that people with evolutionary backgrounds are very employable in #biotech. In fact, they tend to do better than people trained in more narrow topics like cell biology. Folks doing genome evo, please come to industry. We need you.

Oh that’s already taken by the Fed.

#DBfeature

Epithelial and mesenchymal compartments of the developing bladder and urethra display spatially distinct gene expression patterns
by Baraiya, D. H., Kavya, T. T., Mandal, A., Chakraborty, S., Sathish, N., Francis, C. M. R., & Joseph
tiom33.short.gy/DB520,155-170

who will republicans blame for their problems when govt no longer exists?

@smpowers.bsky.social I found you!

Wouldn’t a sufficiently complex system stochastically produce regions of greater complexity?

Trump Officials to Put Almost All U.S.A.I.D. Workers on Leave Most employees overseas have been told to return to the U.S. Democrats have denounced recent moves to shrink the agency as an illegal power grab.

We cut off all foreign aid, stranded 10k people, and saved 1 #%$%#&$ % of the annual budget. Awesome.

www.nytimes.com/2025/02/04/u...

Made a biotech founders starter pack, DM me to be added!

go.bsky.app/LWm8uPE

🎨 In case anyone need…

The NIH BioArt Source is an awesome library of *free* professionally drawn illustrations for scientific presentations or figures. Downloadable in HD. Thank you NIH for this invaluable tool 🙏!

Check it out 👇
bioart.niaid.nih.gov

Can someone please train some AI on large biological datasets like this, integrate with zfin database, and let me query it?

#science #zfin
www.biorxiv.org/content/10.1...