Sonika Tyagi

EMBL-EBI and Google DeepMind renew partnership and release update to AlphaFold Database Deeper collaboration between EMBL-EBI and Google DeepMind brings updates to the AlphaFold Database.

@ewanbirney.bsky.social on the new version of Alphafold at the @emblebi.bsky.social
www.ebi.ac.uk/about/news/t...
AlphaFold has been a transformation not just in structural biology but also - due to its ability to be applied to all proteins - to molecular biology as a whole.

Epidemiologist / Research Data Scientist; Infectious Diseases and International Health in Charlottesville, Virginia, United States of America | Information Management, Services & Technology at Univers... Apply for Epidemiologist / Research Data Scientist; Infectious Diseases and International Health job with University of Virginia in Charlottesville, Virginia, United States of America. Information Man...

My colleagues and I here at UVA are looking to hire a skilled #Rstats developer. You'll be working with me on the project. Here's the posting: jobs.virginia.edu/us/en/job/R0...

AI performs well on facts, but fails when it comes to symptoms | ICT&health Global An important explanation lies in the nature of the language ChatGPT uses. Even more worrying is that it does not indicate when it does not know something.

ChatGPT scores up to 97% on medical facts — yet fails to read symptoms. Experts like Ahmed Abdeen Hamed and Dr Andrew Thornton warn: AI can inform, not diagnose. The real challenge now? Using it responsibly in healthcare. #healthcare

Deepfake Doctors: How AI Spreads Medical Disinformation AI-generated doctors, some fabricated and some mimicking well-known physicians, sell sketchy products and bad medical advice on social media. Here’s how it works.

"Your best defense isn’t your eyes — it’s your brain. Keep practicing media and digital literacy..."

#discover
#MedSky
#MentalHealth
#AI

www.medscape.com/viewarticle/...

The AI Advantage: How Creators Can Use AI to Generate Portfolio Concepts The creative industry is rapidly evolving, and a new co-pilot has entered the studio: artificial intelligence. Creators across fields—graphic designers, photographers, illustrators, writers—often face...

Discover how AI can help creators beat creative block, visualize ideas, and craft standout portfolios—without replacing human creativity. #DataScience #AI #ArtificialIntelligence opendatascience.com/the-ai-advan...

‘Only if we help shall all be saved’: Jane Goodall showed we can all be part of the solution Jane Goodall showed tremendous courage in charting her own course as a pioneering researcher – and working to spread hope wherever she went.

A solemn day as we pay our respects to Dr Jane Goodall and her extraordinary legacy. Vale, Jane, we promise to keep fighting for all that you loved and fought for too!

theconversation.com/only-if-we-h... With @drkyliesoanes.bsky.social, Marissa Parrott, @drvanessapirotta.bsky.social & Zara Bending.

A versatile machine learning pipeline to find co-regulatory modules (CRMs) in DNA.
Check it out and explore: doi.org/10.1016/j.co...

#Genomics #Epigenomics #MachineLearning #CardiacResearch #OpenScience

@tyagilab.bsky.social @tsonika.bsky.social

🩺 Missing medical data isn't just something to fill in or ignore!
EHRs often have missing values. Common fix? Imputation. But filling gaps can mislead predictions.
We explore ML approaches to handle missingness while preserving the original data distribution.
📜 www.researchsquare.com/article/rs-6...

@naimavahab.bsky.social

Congratulations to @yashpalr.bsky.social on his graduation!
@tyagilab.bsky.social

Parents outraged as Meta uses photos of schoolgirls in ads targeting man Exclusive: Instagram pictures of girls as young as 13 were posted to promote Threads site ‘as bait’, campaigner says

Sharenting is the name given to the action of parents sharing photos of their children online.
www.theguardian.com/technology/2...

Toward a Genetic Signature of Resistance to Activity‐Based Anorexia in Striatal Projecting Cortical Neurons Objective Converging evidence from neuroimaging studies and genome-wide association study (GWAS) suggests the involvement of prefrontal cortex (PFC) and striatum dysfunction in the pathophysiology o...

Incredibly proud of @kxhuang.bsky.social for persisting with such a challenging dataset from her PhD! We found some intriguing genetic targets in a corticostriatal circuit that may be involved in the development of #anorexia nervosa 🤔 onlinelibrary.wiley.com/doi/10.1002/...

Well done @kxhuang.bsky.social and good team work @muraliaadhitya.bsky.social 👏🏽

Congratulations 🍾

Speakers — Lorne Genome No description found

Earlybird registration & abstract submissions now open for the 𝟒𝟕𝐭𝐡 𝐋𝐨𝐫𝐧𝐞 𝐆𝐞𝐧𝐨𝐦𝐞 𝐂𝐨𝐧𝐟𝐞𝐫𝐞𝐧𝐜𝐞, 𝟏𝟓-𝟏𝟖𝐭𝐡 𝐅𝐞𝐛 𝟐𝟎𝟐𝟔: https://www.lornegenome.org/registrations (deadline 7th Nov 2025)

Speakers: https://www.lornegenome.org/speakers

We look forward to seeing you there!

Naima is developing foundation models for RNA therapeutic applications.
Fantastic presentation, keep up the good work 🥳

Kudos to Naima Vahab for presenting her PhD research at "Storytelling for Impactful Research (STIR) Competition " at RMIT STEM College. What an amazing opportunity for polishing your #scicomm skills and knowledge sharing across STEM disciplines.

@tyagilab.bsky.social @rmitcomputing.bsky.social

🧠 Just out in Bioinformatics Advances: “Predicting gene expression using millions of yeast promoters reveals cis-regulatory logic”  

Explore the paper here: https://doi.org/10.1093/bioadv/vbaf130

Authors include: @susbo.bsky.social

Scientists detect virus traces in blood that may unlock long COVID’s mystery Scientists have found protein fragments from the COVID-19 virus hidden inside tiny cellular packages in the blood of long COVID patients, offering the first potential measurable biomarker for the cond...

#ProudBlue #Voices4Victory

Science Matters!

Scientists have found protein fragments from the Covid-19 virus hidden inside tiny cellular packages in the blood of long-covid patients, offering the first potential measurable biomarker for the condition.

www.sciencedaily.com/releases/202...

🧬 FOR IMMEDIATE RELEASE SARS-CoV-2 Confirmed as a Vascular Pathogen: New Report Details Mechanisms Behind Acute and Long-Term Damage August 18, 2025 — El Cerrito, CA - A newly revised scientific report by David Lingenfelter, PhD, synthesizes global consensus and cutting-edge research to confirm that SARS-CoV-2 is not merely a respiratory virus—it is a systemic vascular pathogen. The report, originally generated via Google’s Gemini AI and refined through critique and reanalysis, offers a comprehensive account of the virus’s multifaceted assault on the vascular system. 🔍 Key Findings: • Endothelial Dysfunction as Central Pathology: SARS-CoV-2 disrupts vascular homeostasis via Spike protein–ACE2 interactions, Nucleocapsid protein–TLR2 signaling, and immune-mediated inflammation. • Microvascular Injury Drives Organ Failure: COVID-19-associated coagulopathy (CAC), microthrombosis, and vasculitis contribute to acute morbidity and mortality. • Long COVID Linked to Persistent Vascular Damage: Chronic endotheliopathy, fibrinaloid microclots, and senescent “zombie cells” underlie post-acute sequelae. • Vaccination Reduces Vascular Risk: Comparative data show significantly lower rates of cardiac complications post-vaccination versus post-infection. 🧠 Implications for Clinical Practice and Public Health: • COVID-19 should be classified as a systemic vascular disease. • Diagnostic protocols must incorporate endothelial biomarkers and advanced imaging. • Therapeutic strategies should target inflammation, thrombosis, and senescence. • Long-term surveillance is needed to assess cardiovascular risk in survivors. 📚 Future Directions: The report calls for randomized trials of senolytics, microclot-targeting therapies, and personalized vascular risk profiling. It also urges public health systems to prioritize vascular health as a pandemic preparedness measure. 🔗 Full report available on https://davidlingenfelter.substack.com/p/the-vascular-pathophysiology-of-sars-b2d

SARS-CoV-2 causes systemic vascular damage via viral proteins and immune dysregulation, driving acute organ failure and Long COVID.

Vaccination reduces these risks significantly.
davidlingenfelter.substack.com/p/the-vascul...

Scientists Detect “Ghost” Proteins That Could Explain Long COVID Researchers discovered viral fragments in blood samples from long COVID patients, hinting at a possible biomarker. The findings suggest the virus may linger in hidden reservoirs, fueling ongoing sympt...

SciTech Daily: 'Scientists Detect “Ghost” Proteins That Could Explain Long COVID'

'Scientists have uncovered viral protein fragments lingering in the blood of long COVID patients, potentially offering the first measurable biomarker for the condition.'

scitechdaily.com/scientists-d...

Gaps In Maternal Health In Australia, USA, And UK Global study reveals alarming gaps in maternal health - Getty ImagesWomen across Australia, the United States (USA) and the United Kingdom (UK) are

www.miragenews.com/gaps-in-mate...

Contributions to review on graph learning:

The antimicrobial resistance Swiss cheese model

New comment

A layered strategy for tackling antimicrobial resistance: the Swiss cheese model for policy, prevention, and engagement

www.thelancet.com/journals/lan...

#IDSky #ClinMicro #AMR #OpenAccess #OA

Negative binomial regression and inference using a pre-trained transformer Negative binomial regression is essential for analyzing over-dispersed count data in in comparative studies, but parameter estimation becomes computationally challenging in large screens requiring mil...

This looks like a creative use of transformers. Looking forward to diving into this.
arxiv.org/abs/2508.04111

We had a fantastic day for team building and a send-off lunch and marking our mid-season break. It was a lovely opportunity to come together and celebrate, with some intense competition on the bowling lanes! 😆
We will miss having you around at @tyagilab.bsky.social @muraliaadhitya.bsky.social 🙌🏽

Empowering bioinformatics communities with Nextflow and nf-core - Genome Biology Standardized analysis pipelines contribute to making data bioinformatics research compliant with the paradigm of Findability, Accessibility, Interoperability, and Reusability (FAIR), and facilitate co...

🚀 Excited to see this work on "Empowering bioinformatics communities with Nextflow and @nf-co.re" is now published, showcasing the incredible growth and impact of the community.

link.springer.com/article/10.1...

Deep-learning-based gene perturbation effect prediction does not yet outperform simple linear baselines - Nature Methods The analysis presented in this Brief Communication shows that, despite their complexity, current deep learning models do not outperform linear baselines in predicting gene perturbation effects, thus e...

An analysis shows that current deep learning models do not beat linear baselines in predicting gene perturbation effects, thus emphasizing the importance of further method development and evaluation. @const-ae.bsky.social @wkhuber.bsky.social @s-anders.bsky.social

www.nature.com/articles/s41...

RMIT's wearable tech fights infection with smart sensors Researchers from RMIT University have developed a wearable wound monitoring device with integrated sensors that could reduce infection risks by minimising the need for frequent physical contact.

www.news-medical.net/news/2025080...

Age verification is coming to search engines in Australia – with huge implications for privacy and inclusion | Samantha Floreani New rules will radically change the way we use the internet in Australia, and not just social media

Age verification is coming to search engines in Australia – with huge implications for privacy and inclusion

www.theguardian.com/commentisfre...