30S-seq redefines the bacterial Ribosome Binding Site
The translation initiation step is rate limiting for the efficiency of gene expression in all organisms. However, the mechanism of ribosome recruitment to mRNA start sites strikingly differs between e...
I am thrilled to share this new preprint from our lab!
We find (>800!) 30S binding sites in hundreds of 5'UTRs, but also new dynamic steps of translation initiation.
www.biorxiv.org/content/10.1...
Congrats to all co-authors at the RNA control of gene expression lab, IBPC CNRS
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06.04.2025 07:53 — 👍 47 🔁 25 💬 2 📌 5
2/2
The result of a collective effort by all the members of the Rougemaille lab and others, including @jessicaandreani.bsky.social
A work supported by @agencerecherche.bsky.social, @fondationarc.bsky.social, @cnrs.fr and @univparissaclay.bsky.social
05.04.2025 11:15 — 👍 1 🔁 0 💬 0 📌 0
Thrilled to see our story now out at @naturecomms.bsky.social
A shared adventure with Estelle Leroy and Mathieu Rougemaille @i2bcparissaclay.bsky.social, and with the precious help of the @palancadelab.bsky.social
Such a tiny RNA with such a wide range of functions
www.nature.com/articles/s41...
05.04.2025 10:11 — 👍 13 🔁 8 💬 4 📌 0
Happy to share our genetic toolkit designed to make your gene editing (life) easier, faster and very efficient!
Also suitable to build saturated chromosomal variant libraries using oligo-recombineering with extra short homology arms!
www.biorxiv.org/content/10.1...
21.03.2025 07:05 — 👍 40 🔁 23 💬 0 📌 2
Merci beaucoup for your precious contribution to this work !
@I2BCParisSaclay
x.com/ASadylab/statu…
30.03.2023 12:29 — 👍 0 🔁 0 💬 0 📌 0
My main Ph.D project on the role of General Regulatory Factors in protecting promoters from ectopic and divergent transcription initiation is now available. So enthusiastic to finally see the result of this great adventure with @DomenicoLibri @LabLibri
@MolecularCell
x.com/MolecularCell/…
22.12.2018 17:24 — 👍 0 🔁 0 💬 0 📌 0
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Microbiologist at CNRS | Passionate about RNA, 'omics and Bacillus 💻🧫🧬🔬 | Based at Laboratoire de Chimie Bactérienne👩🔬| Soaking up the sun in Marseille☀️🏖️ and its Calanques🌊🥾| Echoes of my postdoc days in Scotland still linger🍸🥃 🏴
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