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Oliviero Leonardi

@olivieroleonardi.bsky.social

Postdoctoral Fellow @Human Technopole Passionate about science and technology

54 Followers  |  74 Following  |  4 Posts  |  Joined: 19.01.2025  |  1.6349

Latest posts by olivieroleonardi.bsky.social on Bluesky

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Evolution and dysfunction of human cognitive and social traits: A transcriptional regulation perspective | Evolutionary Human Sciences | Cambridge Core Evolution and dysfunction of human cognitive and social traits: A transcriptional regulation perspective - Volume 4

3 years ago, Tobias Uller (@biologylu.bsky.social) and I proposed that important human brain-/face-related traits evolved through #downregulation of transcriptional regulation (TR) genes for brain/face development, e.g. ARID1B, ARID2, BAZ1B, CUX1, FOXP2, NFIX, SATB2 & TCF20.
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15.10.2025 21:14 β€” πŸ‘ 6    πŸ” 2    πŸ’¬ 1    πŸ“Œ 0

Kicking off the annual #ASHG meeting in Boston with a brilliant plenary session! Inspiring talks from Sarah Tishkoff and Francis Collins on the importance of representing human genetic diversity in genomic research. Loved seeing human evolution highlighted as a key lens to understand human genetics!

14.10.2025 21:34 β€” πŸ‘ 4    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Thank you so much Cedric, you made a huge difference throughout this journey! I really enjoyed doing science together and learnt a lot from you along the way!

07.10.2025 09:55 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Image credits: Federica Marinaro

Image credits: Federica Marinaro

Thrilled to share that I’ve successfully defended my PhD thesis on human brain evolution at @humantechnopole.bsky.social πŸŽ“ A heartfelt thank you to everyone who has been part of this journey. Excited for what comes next!

07.10.2025 09:43 β€” πŸ‘ 6    πŸ” 1    πŸ’¬ 2    πŸ“Œ 0

Congratulations _Dr_ @olivieroleonardi.bsky.social
on a great thesis defense today. It’s been a great privilege for me to work closely with you for the past 5 years. I have enjoyed our many meetings on paleogenomics and human brain evolution, and learned a lot from you πŸ‘

06.10.2025 10:08 β€” πŸ‘ 5    πŸ” 1    πŸ’¬ 1    πŸ“Œ 0

Incredibly happy to finally share this work in which we uncover the impact of CHD2 dosage on neurodevelopmental timing with implications for human evolution and disease!
Thread below πŸ§΅β¬‡οΈ

22.01.2025 23:42 β€” πŸ‘ 10    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Day 50 cortical organoid stained for KI67 (red), MAP2 (magenta), Hoechst (cyan); image credit: Oliviero Leonardi

Day 50 cortical organoid stained for KI67 (red), MAP2 (magenta), Hoechst (cyan); image credit: Oliviero Leonardi

DIV 28 iNeuron. Homer1 in green and Synapsin1 in purple showing co-localization of post- and pre-synapses, respectively; image credit: Elly Lewerissa

DIV 28 iNeuron. Homer1 in green and Synapsin1 in purple showing co-localization of post- and pre-synapses, respectively; image credit: Elly Lewerissa

New preprint πŸ“£! Excited to share the result of several years of work, led by @ellylewerissa.bsky.social & @olivieroleonardi.bsky.social, in collaboration with friends @naelnadifkasri-lab.bsky.social & Giuseppe Testa. On CHD2, a chromatin remodeller, its role in evolution & development [🧡]
πŸ§ͺ🧠🧫🧬

22.01.2025 10:38 β€” πŸ‘ 44    πŸ” 21    πŸ’¬ 2    πŸ“Œ 5

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