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Gautam Shirsekar

@coevolution.bsky.social

Plant pathologist | Genomics | Coevolution | Wild plant pathosystems | Weigelworld, Max Planck Institute for Biology | Asst. Prof. at the University of Tennessee, Knoxville (EPP)| www.coevolutionlab.org

60 Followers  |  45 Following  |  15 Posts  |  Joined: 22.11.2023  |  1.8702

Latest posts by coevolution.bsky.social on Bluesky

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Come join EEB at the University of Tennessee at Knoxville.

Evolutionary Genomics, Assistant Professor, Ecology & Evolutionary Biology, Fall 2026
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functional and evolutionary genomics in any system 🌱, 🦠, or 🦌 (including πŸ‘«)

28.07.2025 17:49 β€” πŸ‘ 3    πŸ” 6    πŸ’¬ 0    πŸ“Œ 0
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I am Grape!

14.05.2025 19:55 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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#MemPanG25
@thinks.lol

12.05.2025 22:08 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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More #bloomscrolling from the Smokies

05.05.2025 15:36 β€” πŸ‘ 3    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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In the Smokies, on a wild grape hunt

05.05.2025 01:04 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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Pangenomic context reveals the extent of intraspecific plant NLR evolution bioRxiv - the preprint server for biology, operated by Cold Spring Harbor Laboratory, a research and educational institution

6/6 Are you intrigued? Here is our work by Luisa, @kdm9.bsky.social , Max, @aconga.bsky.social
, Theresa, Leon, Justina, Christa, Oliver, Joffrey, Regina, Rosanne, @hajkdrost.bsky.social and @plantevolution.bsky.social www.biorxiv.org/content/10.1...

02.09.2024 22:17 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

5/6 Neighborhoods "expand" & "contract" in accessions and offer a richer picture of NLR evolution in (genomic) space and (evolutionary) time. Why does it matter? Because, NLRs didn't just fell out of a 🌴, they exist in the context of all in which they live and what came before them

02.09.2024 22:14 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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4/6 We constructed a pangenome graph with #pggb
@erikg.bsky.social to crawl along the regions of the genomes where NLRs or pieces of NLRs are found at least in 1 accession UNTIL we found common (syntenic) anchors bordering those regions in all the accessions --> "NLR neighborhood"

02.09.2024 22:13 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

3/6 With a rigorous annotation that involved manual curation and semi-automated decision-making algorithm we pinned down every single NLR (genes, pseudogenes, "protopseudogenes") and even remnants of NLRs.

02.09.2024 22:11 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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2/6 We assembled 17 diverse *A. thaliana* (Ath) genomes using @pacbio.bsky.social #CCS and annotated them using
#isoseq reads that were obtained by challenging these accessions with three different Hyaloperonospora arabidopsidis (Har) strains.

02.09.2024 22:10 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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Pangenomic context reveals the extent of intraspecific plant NLR evolution bioRxiv - the preprint server for biology, operated by Cold Spring Harbor Laboratory, a research and educational institution

1/6 Today is Labor Day in USA and we decided to release the results of our labor and rigor on NLR evolution as a preprint. www.biorxiv.org/content/10.1...

02.09.2024 22:08 β€” πŸ‘ 5    πŸ” 3    πŸ’¬ 1    πŸ“Œ 0
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Wild Flower Festival, Frozen Head State Park, #TN #statepark
#TNPS, Tennessee Native Plant Society #naturalist

15.04.2024 00:48 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Wild Flower Festival, Frozen Head State Park, #TN #statepark
#TNPS, Tennessee Native Plant Society #naturalist

15.04.2024 00:48 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Wild Flower Festival, Frozen Head State Park, #TN #statepark
#TNPS, Tennessee Native Plant Society #naturalist

15.04.2024 00:47 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

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