Jorge Lozano-Juste

New Article: "A combined biochemical and computational approach provides evidence for membrane remodelling by the structural scaffold of the endocytic TPLATE complex" rdcu.be/eP4fX

... to generate a comprehensive structure of the multisubunit endocytic TPLATE complex.

Version 2 is out! More comprehensive text plus new tissue- and pathway-specific analysis revealing how different viruses trigger systemic aging through diverse mechanisms.
www.biorxiv.org/content/10.1...

Our new review is out @theplantjournal.bsky.social! Christian (@unil.bsky.social) and I dive into brassinosteroid perception specificity and the importance of BRs in shaping vascular development. @ibmcp.bsky.social @upv.es @csic.es onlinelibrary.wiley.com/doi/10.1111/...

🌱🧬The #SeminarSeriesCBGP continues!

📅 Friday, November 14th – 12:30 PM
📺 Zoom: shorturl.at/BB2CU (🗝️627464)
🗣️Miguel Ángel Blázquez (@ibmcp.bsky.social)
“Why do plants stop growing under stress?”

#SeminarSeriesCBGP #ScienceTalks #PlantBiology #Research #PlantScience

Bioluminescent sentinel plants enable autonomous diagnostics of viral infections Plants engineered with synthetic genetic programs can transform how we monitor and manage the extension of crop pests and diseases. Here, we establish a bioluminescent platform in Nicotiana benthamian...

Such a cool pre-print on making sentinel plants - so much potential!

Bioluminescent sentinel plants enable autonomous diagnostics of viral infections

www.biorxiv.org/content/10.1...

Check Labbox labbox.eu/product/pes-...

Academic tip: sometimes you have to write "Importantly," to get a sentence started and then you can go back and delete it.

Congrats Juan Carlos!! Great work

Electrostatic changes enabled the diversification of an exocyst subunit via protein complex escape - Nature Plants The evolutionary diversification of an exocyst subunit was enabled by electrostatic shifts leading to its dissociation from the ancestral complex.

My main work as postdoc @plantophagy.bsky.social lab in @gmivienna.bsky.social is out in @natplants.nature.com 🌱🎉

We asked how can protein complexes diversify without compromising their function and explored this question using the plant #exocyst complex.

www.nature.com/articles/s41...

Israeli PM Netanyahu orders military to immediately strike Gaza - live updates It comes as Israel says a coffin handed over by Hamas on Monday did not contain the body of another deceased hostage.

If this being (a human can’t be this cruel) is not a war criminal, who is?!! www.bbc.com/news/live/c8...

El evento “Ultrasonidos de plantas: inteligencia vegetal e IA” nos invita a escuchar las voces del mundo vegetal y su interpretación mediante inteligencia artificial

27 Nov en @casaencendida.bsky.social

www.lacasaencendida.es/encuentros/u...

Had an awesome time at the Medicinal and Crop Protection Chemistry Meeting in Como, Italy 🇮🇹! Great to share our work at this unique event bridging pharma and agro drug discovery. Huge thanks to the organizers for an amazing lineup of speakers from academia and industry! 👏🌿💊

Algal pyrenoids—condensates that mediate ~1/3 of Earth’s CO2 fixation—change size and number as cells divide. Our data suggest a simple control mechanism: a kinase that continuously ejects material from the condensate! ☀️🌍🔬💧 #Biophysics #Photosynthesis
www.biorxiv.org/content/10.1...

Thanks again for the invitation! It was great to see you all and discuss our work with you. Kudos to the organizers for their perfect job!

📢 Don’t miss the upcoming seminar: ‘Drug discovery for thirsty plants’🌱, given by Dr Jorge Lozano Juste, Instituto de Biología Molecular y Celular de Plantas (@ibmcp.bsky.social ). Valencia.

🗓️26 September
🕛12:00h
📍CNB Lecture Hall

Update on translational control modes in plant cell signaling Protein synthesis can contribute to plant cell signaling at multiple regulatory levels. Recent studies have expanded the conditions that are directly …

Very nice new review on roles for translational control in plant cell signalling by @maureynoso.bsky.social

www.sciencedirect.com/science/arti...

Científicos exigen este domingo el cumplimiento del Pacto por la Ciencia firmado en 2023 Varias plataformas convocan concentraciones en Madrid, Barcelona y Valencia para exigir que el Pacto por la Ciencia "no sea papel mojado"

«Entre las demandas principales destacan la aprobación de un Estatuto del Personal de Investigación, la simplificación de trámites administrativos y el incremento de la inversión pública en I+D+i hasta alcanzar el 3% del PIB.»
www.larazon.es/ciencia/cien... vía @larazonlr.bsky.social

'The rise of Chinese pharmaceutical innovation is reflected in the number of new drugs that were approved in China before being approved in any other country, which increased from 9 in 2018 to 45 — not including 3 traditional Chinese medicines — in 2024' www.nejm.org/doi/full/10....

S4.1. Molecular genetic mechanisms of plant development, evolution and adaptation

📢 Multisensory integration during plant terrestrialization - Miguel Blazquez @IBMCP 

#47congresosebbm

Selective ubiquitination of drug-like small molecules by the ubiquitin ligase HUWE1 Nature Communications - Ubiquitination is a versatile modification system in eukaryotic cells. Here, the authors unveil that the ubiquitin ligase HUWE1 can modify drug-like small-molecule...

Delighted to share our work on cellular ubiquitination of drug-like compounds by HUWE1 - a surprising journey! Kudos to all contributors & first authors, Barbara Orth and Pavel Pohl. Sincere thanks to @ireserra.bsky.social ‬ #NatCommun for expertly guiding the winding publishing path.
rdcu.be/eDzPk

We are hiring the second cohort of EvoReSt PhD students. If you are interested in deep evolutionary questions, checkout:
www.uni-goettingen.de/de/687607.html
Apply here:
obp.uni-goettingen.de/de-de/OBF/In...

Cover of Labwork to Leadership

In the new book Labwork to Leadership, chemist Jen Heemstra offers actionable leadership advice to principal investigators.

Read the #ScienceBooks Review: https://scim.ag/4mljVr1

Why so expensive now? I got mine 3 years ago for 1/3 of that

Introducing the 1,000 Flower Collection 🧬🌹

I’m creating 1,000 genetically designed flowers each crafted with new colors, patterns, and shapes.

Here’s how I’m making it happen… and how you can join me on this journey 🧵(1/7)

Accelerating Biomolecular Modeling with AtomWorks and RF3 Deep learning methods trained on protein structure databases have revolutionized biomolecular structure prediction, but developing and training new models remains a considerable challenge. To facilita...

(1/7)
Training biomolecular foundation models shouldn't be so hard. And open-source structure prediction is important. So today we're releasing two software packages: AtomWorks and RosettaFold3 (RF3)

[https://www.biorxiv.org/content/10.1101/2025.08.14.670328v2](www.biorxiv.org/content/10.1...)

This review summarizes advancements in solubility and controllable aggregation tags for recombinant protein purification, highlighting design strategies, on-demand cleavage, and emerging production challenges.
#HM #protein #purification #tags #proteases
www.sciltp.com/journals/hm/...

Totally! I didn't think about that. Looks great btw

RosettaFold 3 is here! 🧬🚀

AtomWorks (the foundational data pipeline powering it) is perhaps the really most exciting part of this release!

Congratulations @simonmathis.bsky.social and team!!! ❤️

bioRxiv preprint: www.biorxiv.org/content/10.1...

Naive question: would it be better with black parts for the root system?