oh, not nearly as good as one might hope
11.08.2025 17:57 โ ๐ 6 ๐ 1 ๐ฌ 2 ๐ 0@drfoxrob.bsky.social
Prof Medicine McMaster. Scientific Dir Sepsis Canada, Dir Med Ed Hamilton Health Sciences.
oh, not nearly as good as one might hope
11.08.2025 17:57 โ ๐ 6 ๐ 1 ๐ฌ 2 ๐ 0Organizations disinvited from CDC vaccine workgroups medicalxpress.com/news/2025-08...
- American Medical Association
- American Academy of Pediatrics
- Infectious Diseases Society of America, et al
Removal "irresponsible, dangerous to our nation's health, & will further undermine public trust..."
Jackie Duda is a BEAST!!! This woman does so much advocating for sepsis awareness & changing lives for the better for all sepsis survivors.
This is her latest article in @thelancet.com.
www.thelancet.com/journals/lan...
Ventilator-associated pneumonia: mechanisms, an appraisal of current therapies and the role for inhaled antibiotics in prevention and treatment
CCR Journal Watch - tracking the critical care literature daily
https://criticalcarereviews.com/latest-evidence/journal-watch
๐ฉThe 3rd trial result for CCR Down Under 2025 is ARISE-AFRICA๐ฉ
โก๏ธStandard low flow oxygen vs nasal high flow oxygen vs CPAP in hypoxaemic respiratory failure
โก๏ธPresenter Arthur Kwizera
โก๏ธJoin us in Melbourne
criticalcarereviews.com/meetings/ccr...
@precordialthump.bsky.social
Nature research paper: Neutrophils drive vascular occlusion, tumour necrosis and metastasis
go.nature.com/4lzilSb
Maria Montessori and her many disciples believed that children are, in their essence, methodical, self-directed beings with a strong work ethic.
20.07.2025 22:02 โ ๐ 450 ๐ 96 ๐ฌ 27 ๐ 9Mastercard Foundation Scholars Program at my university @mcgill.ca
Fully-funded scholarship to Canada!!
opportunitiesforyouth.org/2025/07/14/m...
Tackling misinformation is a long game: journalists can help www.absw.org.uk/resources/ta... v @absw.bsky.social
1) Publish on a topic widely & repeatedly
2) Prebunkโinoculate your audience against common misinformation tactics
3) Report on science with extreme care
4) Choose your experts carefully
Harnessing adiponectin for sepsis: current knowledge, clinical insights and future therapies
CCR Journal Watch - tracking the critical care literature daily
https://criticalcarereviews.com/latest-evidence/journal-watch
Happy to share this collaboration between my undergraduate student, a post doctoral fellow and patient partners healthydebate.ca/2025/07/topi...
08.07.2025 18:52 โ ๐ 1 ๐ 0 ๐ฌ 0 ๐ 0#ICUreadings
One of my favorite recent meditations on the language we use, by the brilliant @jackykruser.bsky.social: pubmed.ncbi.nlm.nih.gov/37486663/
And the classic DAHLIA trial that is part of why I am so liberal with precedex:
pubmed.ncbi.nlm.nih.gov/26975647/
In effort to protect children, France bans smoking at parks, pools, beaches, and or "anywhere children may be present," by @ebeardsley.bsky.social www.npr.org/2025/06/30/n... via @npr.org
30.06.2025 17:50 โ ๐ 35 ๐ 5 ๐ฌ 2 ๐ 0Iโm grateful that these people are willing to share their stories, hopefully so that others can avoid their fate. There is a reason that specific infections have been targeted by vaccines. Vaccine-preventable diseases are terrible.
28.06.2025 17:13 โ ๐ 33 ๐ 12 ๐ฌ 1 ๐ 0An immigration crackdown makes the United States less attractive. Where should you hold your next conference?
https://go.nature.com/407qJ2w
#Measles is surging in Alberta. Which vaccine-preventable disease could be next? Measles 'canary in the coalmine,' as experts watch for resurgence of illnesses like polio, by @jenleecbc.bsky.social www.cbc.ca/news/canada/... via @cbcnews.ca #pediatrics
16.06.2025 12:24 โ ๐ 81 ๐ 38 ๐ฌ 2 ๐ 4#Measles leaves children vulnerable to other diseases for years. Measles causes more than an acute illness: it suppresses immune memory and increases the risk of complications for years, by @scientificdiscovery.dev โฌ ourworldindata.org/measles-incr... via @ourworldindata.org
16.06.2025 17:31 โ ๐ 70 ๐ 41 ๐ฌ 1 ๐ 1Today's Paper of the Day is:
Protocolized strategies to encourage early mobilization of critical care patients: challenges and success
criticalcarereviews.com/latest-evide...
Join us to read 1 paper per day and stay up-to-date as we cover the spectrum of critical care across 2025
A graph showing the cumulative probability of successful liberation from ventilation and of death before successful liberation.
In the PROMIZING trial, proportional-assist ventilation with load-adjustable gain factors did not differ significantly from pressure-support ventilation with respect to the time to liberation from mechanical ventilation. Full trial results: nej.md/4kC2a67
@criticalcarereviews.com #CCR25
#PROMIZINGtrial results are in - no difference in time to successful liberation from mechanical ventilation between proportional-assist ventilation and pressure support ventilation
#CCR25
Forest plots of the subgroup analyses
Presented at #CCR25:
In a cluster-randomized, crossover trial, hospital-wide use of lactated Ringerโs solution as compared with normal saline did not alter the incidence of death or hospital readmission within 90 days. Full trial results: nej.md/45SaEBs
@criticalcarereviews.com
Flyer for the FLUID trial results at CCR25
๐จ FLUID Trial Results๐จ
Balanced crystalloids vs saline in hospitalised patients
๐ 16 Canadian hospitals
๐ฅ >144,000 pts ๐ฎ
๐ Cluster-crossover RCT
๐ 90-day death or readmission
โก๏ธ Big trial !
โก๏ธ Big numbers !
๐ฉ The answer drops at #CCR25๐ฉ
BาAาCาTาEาRาIาAาLา าEาNาEาRาGาYา าVาAาMาPาIาRาEา
๐๐ฆ๐จ๐ช๐ฐ๐ฏ๐ฆ๐ญ๐ญ๐ข ๐ฑ๐ฏ๐ฆ๐ถ๐ฎ๐ฐ๐ฑ๐ฉ๐ช๐ญ๐ขโs Dot/Icm system secretes actin-dependent ATPase Ceg14 to the cytoplasm
Ceg14 depletes ATP;
metaeffector AnkJ restrains its activity
Resultโdynamic regulation of host energy stores to favor bacterial replication
www.nature.com/articles/s41...
Private health clinics in Canada are selling patient information: study
www.ctvnews.ca/health/artic... @ctvnews-rss.bsky.social
Oncologists call cancer a disease. Why do intensivists call sepsis a syndrome? A disease is a disorder that affects how your body functions with a known cause, a distinct course and established treatments. If we called sepsis a disease we might have investment in finding therapies just like cancer.
10.05.2025 14:43 โ ๐ 1 ๐ 0 ๐ฌ 0 ๐ 0CDC reports 216 child deaths this flu season, the most in 15 years www.statnews.com/2025/05/02/c... via @statnews.com
Big reason: fewer getting flu vaccine, which is "highly effective at preventing hospitalizations and deaths."
#VaccinesWork & misinformation kills.
There has been a significant reduction in the number of kids getting the flu vaccine over the past 5 yearsโa drop from 64% to 49%.
Consequently, there have been 216 pediatric flu deaths so far this flu season, the highest number since the swine flu 15 years ago (link below).
Vaccinate.
"Health systems can take steps to mitigate inhaler-related greenhouse gas emissions expeditiously."
This Perspective discusses the environmental impact of metered-dose inhalers used for respiratory conditions.
#MedSky ja.ma/4cWmpbL
Here we go. A major conference on antimicrobial resistance (GAMRIC) scheduled for later this year has been moved from Washington DC to London. Email from the organizers: "In order to maximise global participation..."
(NB that they say nothing about moving *from* DC. But it WAS in DC.)
๐งช
Receiving a COVID-19 booster vaccine in the same arm as the first vaccine dose leads to a faster, more effective immune response than having it in the opposite arm.
https://go.nature.com/42WwKzT