EpiCypher

One experiment. Multiomic insights.

CUTANA™ Fiber-seq captures chromatin accessibility, protein footprints, DNA methylation, and more in ONE assay—saving time, samples, & budget.

Interested in Fiber-seq Services? Start here: https://www.epicypher.com/services/cutana-fiber-seq-assay-services/

🎥 The webinar recording is now live!

Catch up on insights from Zach Freeman, DVM, PhD and Emily Madden, PhD on how Fiber-seq + PureTarget™ reveal hidden integration and expression issues.
Replay here: https://app.livestorm.co/epicypher/combining-fiber-seq-and-puretarget

#Epigenetics #Chromatin

It’s webinar day! 🎉

Join us at 3PM EST for a deep dive into Fiber-seq + PureTarget™ with Zach Freeman, DVM, PhD and Emily Madden, PhD.
Still time to register: https://app.livestorm.co/epicypher/combining-fiber-seq-and-puretarget

#Epigenetics #GenomeEngineering

The wait is almost over ⏳

Our webinar on Fiber-seq + PureTarget™ goes live tomorrow! Zach Freeman, DVM, PhD and Emily Madden, PhD will share new insights + tips for transgene analysis.
Grab your spot: https://app.livestorm.co/epicypher/combining-fiber-seq-and-puretarget

#Epigenetics #CRISPR

🔔Join us next Wednesday for #FragileNucleosome! 2 fantastic talks on chromatin regulation:🔬 @mariamafau.bsky.social on ZIC2's dual role in neural induction 🔬 @jhenninger.bsky.social on how RNA-binding proteins drive transcription
📋Register here for the entire series: us06web.zoom.us/webinar/regi...

Grateful for every scientist mapping the epigenome, sharing data, or troubleshooting at midnight. Whether you’re celebrating Thanksgiving or not, thanks for being part of our community 🧬💡 #Epigenetics #ScienceLife

🚨 One-week countdown!

Don’t miss this free webinar on Fiber-seq + PureTarget™ for uncovering transgene integration and regulation issues.

📆 Dec 3 @ 3PM EST – sign up here: https://app.livestorm.co/epicypher/combining-fiber-seq-and-puretarget

#Epigenetics #CRISPR

How do reader proteins interact with chromatin to regulate biological processes?

📢 A new study shows how nucleosome context shapes chromatin reader specificity — a key insight for understanding disease mechanisms & therapeutic targeting.

📄 Read here: https://pubmed.ncbi.nlm.nih.gov/41182902/

Explore CUT&RUN, a revolutionary epigenomic mapping tool for understanding the role of the epigenome in scientific research, with @epicypher.bsky.social
humangenetics.ucsf.edu/ucsf-ihg-cat...

How pairing EpiCypher’s Fiber-seq with HiFi sequencing delivers an all-in-one multiomic view - PacBio Fiber-seq with PacBio HiFi sequencing is changing how researchers study epigenetics, advancing discoveries in development and disease.

@epicypher.bsky.social's Fiber-seq paired with #PacBio HiFi sequencing offers a single-assay, multiomic view of chromatin by capturing sequence, accessibility, methylation, and protein interactions together. See how this approach improves chromatin insights.

Read the full blog here: bit.ly/3JIKrgg

Your genome-edited models might be hiding more than you think. 🧬

Learn how Fiber-seq + PureTarget™ help uncover integration and expression issues in transgenic lines. Webinar Dec 3.
Register here: https://app.livestorm.co/epicypher/combining-fiber-seq-and-puretarget

#Epigenetics #GenomeEngineering

That’s a wrap on #SfN2025! 🧠
Grateful for all the great chats on Fiber-seq, CUTANA™ Cloud, and FFPE-based chromatin profiling in the brain.
#Epigenetics #Neuroscience #FiberSeq

Aaron presented at #SfN25 this week, highlighting how our CUTANA CUT&Tag tech is unlocking FFPE samples for chromatin profiling. A big step for epigenomics in neuroscience.

Poster link: https://explore.epicypher.com/posters/sfn2025/advance-neuroscience-research

#Chromatin #Epigenetics

Grateful to have joined the MSKCC Epigenetics Meeting—a standout event full of powerful science and heartfelt goodbyes. Tony Kouzarides’ final lecture was a true masterclass. Hats off to Dr. Yael David for the incredible organization. #Epigenetics #ScienceCommunity

Join our Live Webinar! Zach Freeman, DVM, PhD, will discuss using Fiber-seq with PacBio's PureTarget™ for transgene insights. Plus, Emily Madden, PhD, will provide practical tips for getting started with Fiber-seq.

Register Now: https://app.livestorm.co/epicypher/combining-fiber-seq-and-puretarget

Visit our poster at #SfN25 to learn how innovations in CUT&Tag technology are opening new doors to study both the epigenetic and transcriptional landscapes of FFPE tissues.

Can’t attend? View Aaron Alcala’s poster here: https://explore.epicypher.com/posters/sfn2025/advance-neuroscience-research

Day 2 of #SfN2025 is a wrap! Now, we're energized for Day 3! ⚡

Missed us yesterday? Don't worry! Stop by Booth #901 TODAY to see our NEW product and learn how it's accelerating neuroscience research!

#NeuroEpigenetics #SfN #BrainResearch

🔔This Wednesday , in #FragileNucleosome seminar, we are excited to host @ishtiaqueh.bsky.social of Pastor lab and Prof. Sarah Teichmann, @teichlab.bsky.social, to tell us about their exciting studies!
🗓️Register here for upcoming session and the entire series:
us06web.zoom.us/webinar/regi...

Kicked off #SfN2025 strong yesterday.
Great talks, great people, and even better science. We’re here for Day 2 and excited to keep the momentum going.

Swing by the booth and let’s talk epigenetics 🧬

#Epigenetics #ChromatinBiology

🧠 Attending #SfN2025?

Check out four ways CUT&RUN and CUT&Tag are advancing neuroscience — from neurodevelopment to pediatric brain cancer and neuro-immune crosstalk.

Read our blog here: https://www.epicypher.com/resources/blog/sfn-neuroscience-chromatin-profiling/

“Together, we’re empowering researchers to explore the epigenetic mechanisms that control gene regulation, and to turn those discoveries into better treatments and improved patient outcomes.” Press Release: EpiCypher Launches CUTANA® Cloud, a Powerful Epigenomic Data Analysis Platform

We’re excited to announce the launch of @epicypher.bsky.social’s new bioinformatics platform CUTANA Cloud. Built on the DNAnexus precision health platform, CUTANA Cloud provides researchers with fast, accessible epigenomic analysis. www.dnanexus.com/press/epicyp...

#DrugDiscovery #Genomics

@epicypher.bsky.social's is new Fiber-seq Kit works with PacBio long-read sequencing to reveal chromatin accessibility, DNA methylation, and protein footprints on single molecules, expanding access to powerful multiomic analysis.

Learn more: bit.ly/4qSMa3d

🧠 Headed to #SfN2025 in San Diego? We’ll see you there!

Exhibits start Sun, Nov 16 — visit EpiCypher Booth 901 to explore the latest in Fiber-seq, CUTANA™ Cloud, CUT&RUN & CUT&Tag.

Let’s advance #epigenetics & #neuroscience together.
#ChromatinMapping

Fiber-seq is your complete solution for profiling chromatin accessibility, DNA methylation, and protein footprints in ONE multiomic experiment. This kit contains everything you need to get this assay up and running in your lab.

🔗 Try CUTANA™ Fiber-seq: https://www.epicypher.com/products/fiber-seq/

On this #VeteransDay, we honor those who serve — in the armed forces and in science. Your resilience inspires our work to advance epigenetics, from stress response to immune health. Thank you. 🔬🧬

@epicypher.bsky.social  CUTANA™ CUT&RUN #chromatin mapping services are increasingly valuable for elucidating disease mechanisms and determining treatment impact. 

Ask us about the power of CUT&RUN for #drugdiscovery. 

🔗https://www.stratech.co.uk/our-partners/epicypher/#1628242246006-daba23e6-d456

EpiCypher is headed to #SfN2025 in San Diego!
Find us at Booth 901 to explore Fiber-seq, CUTANA™ Cloud, and chromatin tools designed for neuroscience discovery 🧬 #Chromatin #Epigenetics

That’s a wrap on EpiCypher 2025 🧬
Cancun brought the sunshine and the science. From posters to hallway chats, the passion in this community is undeniable. Thanks to all who shared their work with us.

Here’s to what comes next. #Epigenetics #Chromatin

Our #Epi2025 Workshops were a huge success yesterday! Thanks to our #EpiExperts for leading immersive sessions on CUT&RUN and Fiber-seq, sharing cutting-edge methods shaping the future of epigenomics. We are looking forward to our workshop on Cutana Cloud today! 👩‍🔬