Romain Koszul

We are hiring!

Institut Pasteur (@pasteur.fr) is recruiting new young PIs to open new groups in the Institute. Deadline is February 9th! Don't miss the opportunity!

Amsterdam prepares to ‘ban the fatbikes’ amid rise in serious accidents Experts say souped-up e-bikes pose big risk for children aged from 12 to 15, who account for many A&E cases

Un peu de lecture @paris.fr

www.nytimes.com/2025/11/30/m...

www.nytimes.com/2025/11/30/b...

www.theguardian.com/world/2026/j...

Complex question 🤔

Bacteria chromosomes contain Genomic Islands that provide virulence, antibiotic resistance, MGE-defence,... They transfer between cells, but the mechanism of most remains elusive.

Here we explore the conjugative capacity of these mysterious Genomic Islands.

www.biorxiv.org/content/10.6...

Last work of the lab showing that Repeated losses of self-fertility shaped heterozygosity and polyploidy in yeast evolution | PNAS www.pnas.org/doi/10.1073/...

Seeking expressions of interest from researchers abroad for a Canada Impact+ Research Chair ($1M/year × 8 + up to $6M CFI) in AI-enabled antibiotic discovery and/or AMR, phage & phage-based derivatives. Email me a short vision, CV, and 3–5 key papers. Deadline: March 10, 2026 (Intake 2: June 15).

En évitant les trottoirs et marchant sur la chaussée ça passait à peu près...

Les magistrats ayant condamné Marine Le Pen dans le viseur de l’administration Trump - L'Humanité Le gouvernement états-unien entend multiplier les sanctions individuelles contre des personnalités européennes, à l’image de l’ancien commissaire européen Thierry Breton,...

#USA - Le gouvernement états-unien entend multiplier les sanctions contre des personnalités européennes, à l’image de l’ancien commissaire européen Thierry Breton, interdit de visa. Les magistrats qui ont condamné Marine Le Pen en mars dernier seraient menacés.
#AnticorVeille

RFK, Jr.–Backed Lyme Disease Conspiracy Theory May Be Probed under New Bill President Donald Trump is expected to sign a defense bill this week that orders an investigation into whether the U.S. military bioengineered Lyme disease

RFK, Jr.–Backed Lyme Disease Conspiracy Theory May Be Probed under New Bill

www.scientificamerican.com/article/rfk-...

President Donald Trump is expected to sign a defense bill this week that orders an investigation into whether the U.S. military bioengineered Lyme disease

Creation of new junior research groups at the Institut Pasteur - Call for applications 2026 - Research The Institut Pasteur is launching an international call to recruit new junior research group leaders leveraging cutting-edge transdisciplinary approaches to exploring infectious diseases, host-microbe...

🔬 Call to create junior research groups at the Institut Pasteur

Focus: Infectious diseases, host-microbe interactions, vaccines
Special interest: AI methodologies

📅 Deadline: Feb 9, 2026
👥 2-12 years post-PhD

Apply now 📝 research.pasteur.fr/en/call/crea...

#JobOpportunity #Research

#RejoignezLeCNRS 🫵 Les concours chercheurs CNRS 2026 ouvrent le 8/12 !
Envie de faire avancer la science au sein d’un des plus grands organismes de recherche ?
👉 carrieres.cnrs.fr/concours-...

#ConcoursChercheurs #Science #Recherche #Icicarecrute #recrutement

Avian-origin influenza A viruses tolerate elevated pyrexic temperatures in mammals Host body temperature can define a virus’s replicative profile—influenza A viruses (IAVs) adapted to 40° to 42°C in birds are less temperature sensitive in vitro compared with human isolates adapted t...

How does fever work?

Our new Science paper shows how elevated body temperature can protect against severe influenza and that avian-origin viruses escape this defence.

This is likely one reason why bird flus and some pandemic influenzas can be so severe.🧵

www.science.org/doi/10.1126/...

Given the example of qedscience, which - in my opinion and for the few papers I tested - has learned the worst reviewing practices imaginable and delivers reviewer 3 unrealistic and picky comments to the power 10, I still prefer an unmotivated human to an AI :-)

Alors si j'ai bien compris oui pour certains revenus, mais seulement si on paie moins d'impôts localement que ce qu'on aurait payé aux USA.
On est pas imposé 2 fois.

Beyond the Ballot Quiz - The Survey Center on American Life

Take this quiz to die instantly www.americansurveycenter.org/quiz/

#JobOffer

💼 Un poste susceptible d’être vacant de Professeur en stabilité des génomes devrait s’ouvrir pour la rentrée 2026 au sein de l’Institut Jacques Monod

➡️ Informations concernant ce poste et la procédure de candidature 🔗 www.ijm.fr/poste-de-pro...

Excited to share our new #biorxivpreprint:
“Sexual dimorphism in the complete connectome of the Drosophila male central nervous system” www.biorxiv.org/content/10.1...

We describe the #connectomics reconstruction and analysis of an entire adult #maleCNS #drosophila central nervous system. 1/10

Manipulations génétiques, virus créés par l’IA, bactéries miroirs : quelles limites à la recherche scientifique ? Elles pourraient aider à lutter contre les cancers… mais aussi détruire toute trace de vie sur Terre ! Ce sont les bactéries miroirs. En avez-vous déjà entendu parler ? Et la vie miroir, ça vous dit q...

Entretien pour Brut sur la vie Miroir, l'ingénierie génétique et l'éthique de ces recherches: www.brut.media/fr/videos/sc...

We're now recruiting early career group leaders at the Crick to lead ambitious research programmes and explore bold scientific questions.

Hear our Director, Edith Heard, explain why the Crick is a unique place for curiosity-driven research.

Apply now ➡️ www.crick.ac.uk/careers-stud...

How do SMC complexes load onto DNA to get ready for loop extrusion?

@roisnehamelinf.bsky.social & co discovered that Wadjet, an SMC complex involved in bacterial DNA immunity, performs some impressive molecular gymnastics 🤸‍♂️🤸‍♂️🤸‍♂️.

Check out the new paper: www.cell.com/molecular-ce...

Research engineer in Bioimage Analysis for the researchers of the inIdEx FORMULA Hi all We are looking for a bioimage analysis to work in an image analysis core facility in beautiful Paris. Can I ask you to share this opportunity with your networks? The position is in the Instit...

Job alert!

We are looking for a bioimage analysis to work in an image analysis core facility in beautiful Paris. Can I ask you to share this opportunity with your networks?

See also on the forum:
forum.image.sc/t/research-e...

Independent research fellowships leading to tenured positions at the John Innes Centre.

Repost = nice. Thank you very much!!!

Dynamics and interplay of gene expression and chromosome organization across a predatory lifecycle The obligate predatory bacterium Bdellovibrio bacteriovorus alternates between a motile attack phase and a growth phase inside another bacterium, during which it undergoes multiple rounds of DNA repli...

📝New preprint! #MicroSky

🕰️We chart the full, synchronized lifecycle of a predatory bacterium using Hi-C, RNA-seq, ChIP-seq & microscopy.

🧬We uncover dramatic shifts in nucleoid architecture & transcription, tightly coordinated with predation.

www.biorxiv.org/content/10.1...

Pour un licencié en droit on aurait pu espérer plus de discernement...

What’s more astonishing: 1) that the president clearly believes, and repeatedly suggests, that asylum seekers are people from mental asylums, or 2) that no journalist has ever challenged him on this and no mainstream media outlets have done any deep dives on this story?

ceci dit 40 avec les gros mollets c'est vraiment de plus en plus rare à Paris... par contre du motorisé débridé ou pas qui s'impatiente collé à ton siège enfant quand tu montes une côte avec un gamin...

New paper!
We generated and/or (re)analyzed ~100 #metagenomics Hi-C datasets to provide a comprehensive analysis of bacterial and viral metagenomes across VERY different environments.
Congratulations to all authors especially Amaury Bignaud and @mmarbout.bsky.social for the huge work!
#metaHiC

Repeated losses of self-fertility shaped heterozygosity and polyploidy in yeast evolution Evolutionary transitions in mating strategy have profound consequences for genetic variation and adaptation. In Saccharomyces cerevisiae, mating-type switching is a central feature of the life cycle t...

New preprint from the lab: we show that the ability to switch mating type was lost at least 13 times independently in the evolution of S. cerevisiae. At least 27% of isolates are heterothallic with a strong association with polyploidy and heterozygosity
www.biorxiv.org/content/10.1...

A host organelle integrates stolen chloroplasts for animal photosynthesis Sea slugs steal foreign chloroplasts and store them in specialized organelles that facilitate photosynthesis and eventual digestion to mediate starvation resistance.

www.cell.com/cell/abstrac...

A host organelle (in sea slugs) integrates stolen chloroplasts for animal photosynthesis