Centre for Structural Systems Biology CSSB

Congrats to Thomas Mulvaney from the @topf-lab.bsky.social for his Nomination for the Leibniz Association’s Dissertation Award — a great recognition of his innovative work on integrative modeling of proteins and nucleic acids. #ResearchExcellence

@leibnizliv.bsky.social
@cssbhamburg.bsky.social

MHH invites applications for a W1 university professorship for Systems Virology at CSSB. The research focus should be on analyzing viral infections using innovative, systemwide methods to elucidate virus-virus and virus-host interaction networks.

More info: t1p.de/nag2v

@bosse-lab.bsky.social

CSSB group leader Jens Bosse @bosse-lab.bsky.social @resist-cluster.bsky.social and CSSB associate member Chris Meier @uni-hamburg.de , together with Hans-Achim Wagenknecht from the Karlsruhe Institute of Technology, have developed a new method for live-cell RNA imaging

Find out more: t1p.de/18suk

The Krey lab is hiring! If you are interested in viral glycoproteins, neutralizing antibodies and vaccines - and you want to further study this using structural and biochemical approaches, please apply!
stellenangebote.uni-luebeck.de/jobposting/d...

Join CSSB! The Sondermann lab is interested in deciphering the molecular processes that determine bacterial interactions in microbial communities. They are looking for a PhD candidate to investigate the bacterial secretion systems involved in these processes.

Apply now: v22.desy.de/e67416/recor...

An international research team headed by the Bozdech lab at the Nanyang Technological University and the Gilberger lab (BNITM @uni-hamburg.de) at CSSB reveals the global landscape of protein-protein interactions that govern the biology of the malaria parasite.

Find out more: t1p.de/puyln

Researchers from @topf-lab.bsky.social, @embl.org, and IIT have visualised how a large RNA molecule assembles itself into a functional machine, revealing a dynamic choreography that helps us better understand structural folding and misfolding, almost frame by frame.

More information: t1p.de/tt2hk

📣Join us on December 9 for the Academia-Industry Matchmaking Workshop, focused on innovative solutions for challenges in the Life Sciences.

Registration: indico.desy.de/event/50931/

@landaulabcssb.bsky.social @leibnizliv.bsky.social @uni-hamburg.de @fzborstel.bsky.social

Using a combination of X-ray crystallography and cryo-EM, a new study from @landaulabcssb.bsky.social shows that amyloids,form different structures that could be useful as a natural mechanism of immune protection.

More info: t1p.de/4n8se

@amyloid-sam.bsky.social @emilgustavsson.bsky.social

The Barisch lab held a 2 week practical module called 'Molecular Master Thieves' including an excursion to FZB. It was amazing & inspiring to see the students' enthusiasm & curiosity.

We wish you all the best for your bright careers!
@carobarisch.bsky.social @fzborstel.bsky.social @uni-hamburg.de

Clathrin adaptors drive phase separation in endocytosis and trafficking Liquid-liquid phase separation (LLPS) underlies the formation of biomolecular condensates that organize cellular processes, including endocytosis and membrane trafficking. Although LLPS has been impli...

New preprint out!📃

This work uncovers how the clathrin adaptors Ent5 & Sla2
undergo LLPS, revealing distinct structural drivers that shape endocytic and trafficking dynamics.

@lucasdefelipe.bsky.social @katharinchen.bsky.social @embl.org @cssbhamburg.bsky.social

👉 www.biorxiv.org/content/10.1...

On Wednesday afternoon, students who are part of DESY's ELB-Akademie programme visited CSSB. The students learned about our molecular infection research and visited the @landaulabcssb.bsky.social and our ALFM and cryo-EM facilities.

Find out more about the ELB-Akademie: t1p.de/w89j6

Congratulations to the Hamburg iGEM team for winning a gold medal in Paris for their project DeathCapTrap. @uni-hamburg.de @igemhq.bsky.social @igemcommunity.bsky.social

Find out more: t1p.de/dtho1

Are you looking for female speakers in CryoEM for seminars and conferences? Are you a woman in CryoEM and not yet on the ‚woman in CryoEM‘ list? Find your speakers and add/update name and affiliation! docs.google.com/spreadsheets...

Not only our figures in paper but the sky outside CSSB is also colourful.

@cssbhamburg.bsky.social @landaulabcssb.bsky.social

Congratulations to Gabriele Diana, a PhD Student in the @topf-lab.bsky.social, who received the Italian Crystallographic Association (AIC) award “Fiorenzo Mazzi” for Best Crystallographic Thesis 2025.

Find out more: t1p.de/a8yuf

@bosse-lab.bsky.social, @landaulabcssb.bsky.social

Holger Sondermann (DESY, @uni-kiel.de) Scientific Director of CSSB, recently presented the Plenary Lecture of the Pan American Association for Biochemistry and Molecular Biology (PABMB) at SAIB 2025 in Córdoba, Argentina. @fbsisti.bsky.social

Find out more: t1p.de/3alk9

We are hosting another “academia meets industry” workshop this December 9th (Tue) from 16:00-20:00 at CSSB, DESY. This is a great opportunity to connect with members of industry for translational projects or future job opportunities. Registration details will follow in the near future.

Save the date for another exciting "academia meets industry" event!
@cssbhamburg.bsky.social @evotec.bsky.social

The latest work from the Marlovits group in collaboration with the Sartori group. Victor used Elastic Strain Analysis to complement Jiři's original Staring at the Structures for Ages Analysis and understand the chemo-mechanical coupling of the RuvAB AAA+ ATPase

Congratulations to the @uni-hamburg.de's MIN Faculty on its 20th Birthday!

@carobarisch.bsky.social @cui-unihh.bsky.social

Unser RZ sucht für das @cssbhamburg.bsky.social in Hamburg derzeit eine studentische Hilfskraft (m/w/d) zur Unterstützung im IT-Bereich (bis zu 50 h/Monat). www.helmholtz-hzi.de/karriere/job.... Alle weiteren offenen Stellen findet ihr in unserem Jobportal: www.helmholtz-hzi.de/karriere/job...

Yesterday’s NGMI3 symposium @fzborstel.bsky.social was a real highlight 🎉 Great keynotes, inspiring discussions & a lot of fun! Many thanks to #NDI3, #Nordinfect & Oliver JT who did such a great job👏
@oneyrolles.bsky.social, @maxgg.bsky.social, Susanne Häussler, Silke Meiners & Christian Karsten!

A big thank you to our Scientific Advisory Board for their engagement during out meeting this week. So many thoughtful questions and insightful comments!

Hans-Georg Kräusslich, @oneyrolles.bsky.social,
@sykhalid.bsky.social, @thamlab.bsky.social,
Joost Enninga, Friedrich Förster, Ilaria Ferlenghi

Incredible two days @cssbhamburg.bsky.social as Scientific Advisory Board and to hear about integrative structural biology for infectious diseases 🦠🧫🔬

🙏Hans-Georg Kräusslich, @oneyrolles.bsky.social , @sykhalid.bsky.social Joost Enninga, Friedrich Förster, Ilaria Ferlenghi for open discussions

‪
Day 1 of our Scientific Advisory Board meeting is off to a great start. Scientific talks, lunch at @mpsdhamburg.bsky.social
and a tour of #DESY 's FLASH.

Looking forward to our poster session.

@oneyrolles.bsky.social @sykhalid.bsky.social
@thamlab.bsky.social

Poster Session during our SAB Meeting!

Thanks to everyone who shared their research with our SAB members.

@landaulabcssb.bsky.social @topf-lab.bsky.social @bosse-lab.bsky.social @jankosinski.bsky.social @thamlab.bsky.social @oneyrolles.bsky.social @sykhalid.bsky.social

Really fun visit to @cssbhamburg.bsky.social in Hamburg as a scientific advisory board member. It’s not over yet tho’ - more work for the board tomorrow.

What an incredible center, @cssbhamburg.bsky.social! In just 8 years, you’ve become an essential hub for structural infectiology. 👍💪💪

Structural and Functional Versatility of the Amyloidogenic Non‐Amidated Variant of the Antimicrobial Peptide Citropin 1.3 Citropin 1.3 is an antimicrobial peptide derived from amphibians that forms amyloid structures. Here, the structural and functional properties of citropin 1.3 are characterized. Using high-resolution...

I’m thrilled to share my latest published manuscript, which summarizes my work in the exciting fields of structural biology and amyloid research. A huge thank you to @meytallandau.bsky.social and the team at @landaulabcssb.bsky.social for their shared efforts
doi.org/10.1002/advs...

We had the pleasure of hosting Said Azaizah, Shay Sosnovsky, and Ella Zinger for a short stay at @cssbhamburg.bsky.social
It was a joy to see your curiosity, enthusiasm, and smiles brighten up the lab. Thanks Alex, @hiijanina.bsky.social and the rest of @landaulabcssb.bsky.social for mentoring!