MRC Laboratory of Molecular Biology

SynHG logo, with letters Syn coloured orange, H represented by an image of a paired chromosome, followed by capital G in black.

New pipeline to implant human chromosomes into mouse cells and back again signals first step in mammoth undertaking to synthesise the human genome.

Read more about the achievement from LMB’s PNAC Division as part of the SynHG project: www2.mrc-lmb.cam.ac.uk/transplant-o...

#LMBResearch

Brian Cox, Madeline Lancaster and fellow panel member sat on stage with microphones.

Can we build a human?

Madeline Lancaster joined Brian Cox & a panel of experts for the @crick.ac.uk & BBC Studios podcast A Question of Science, to answer this question.

Find the episode here: www.lnk.to/AQOSBioengin...

#LMBintheNews

@cellbiol-mrclmb.bsky.social @lancasterlab.bsky.social

Ana Tufegdžić Vidaković at a lab bench

Congratulations to @anatv.bsky.social, Group Leader in the LMB’s PNAC Division, who has joined @embo.org’s Young Investigator Programme!
Read more about the programme and Ana’s research here: www2.mrc-lmb.cam.ac.uk/ana-tufegdzi...
#LMBNews

Now hiring: IT Assistant Aiding the LMB’s IT team with various tasks, including preparing new computers for users and cataloguing waste. Apply by 11th December

We’re looking for an IT Assistant to join the LMB. Responsibilities include preparing new computers for users, installing software and cataloguing computer waste.
Read more about the role here: mrc.tal.net/vx/mobile-0/...
Apply by 11 DEC
#CambridgeJobs #ITJobs

EMBL Council announces next EMBL Director General | EMBL EMBL Council has elected the organisation's next Director General, Anthony Hyman, who assumes the role 31 March 2026.

Congratulations to Tony Hyman, announced as the next Director General of @embl.org!
Having completed his PhD in @cellbiol-mrclmb.bsky.social, Tony becomes the second #LMBAlumni to hold the position of EMBL Director General, following EMBL founder John Kendrew.
More: www.embl.org/news/people-...

Check out the latest paper from Leo James and William McEwan which explains the science behind LMB spin out TRIMTECH Therapeutic's TRIMTAC® degraders ⤵️

A large screen shows David Attenborough and the title ‘OCEAN’

Five women stood below a sign reading ‘Max Perutz Lecture Theatre’

Earlier this week, the LMB held a viewing of ‘Ocean with David Attenborough’.
After the film, viewers were joined by Elisabeth Goodman Spain, Judy Hirst and Sue Wells who discussed how they have incorporated sustainability initiatives into their workplaces and local communities.
#GreenLMB

Join the LMB's PhD programme! Applications now open for October 2026 Deadline 2nd December 2025

There’s just ONE WEEK left to apply to join our amazing PhD programme next year!
Visit our website for more information: www2.mrc-lmb.cam.ac.uk/students/int...
Applications close on 2nd DEC 2025

Now hiring: Assistant Divisional Administrator Structural Studies Division Provide administrative support to scientists, act as the first point of contact for the division, and manage tasks such as onboarding, orientation, and day-to-day office coordination. Apply by 2nd December

Excellent opportunity for an enthusiastic person to join the LMB, providing administrative assistance to scientists in our Structural Studies Division across a diverse range of topics.
More info: www.jobs.ac.uk/job/DPM745/a...
Closes 02 DEC
#CambridgeJobs

Martin, sat at a wooden desk, speaking whilst gesturing with his hands in front of him.

The LMB is deeply saddened to share that Martin Kyte, Senior Design Engineer in the Electronics Workshop, died suddenly on 3rd November 2025.
A popular and trusted member of the LMB for over 30 years, Martin will be sorely missed.
www2.mrc-lmb.cam.ac.uk/martin-kyte-...
#LMBNews

Csilla Biro, stood against a glass wall in the LMB atrium

Earlier this year, the LMB was thrilled to appoint Csilla Biro as the new Domestic Services Manager, overseeing cleaning and waste disposal services across the LMB.
Read more about Csilla and the team here: www2.mrc-lmb.cam.ac.uk/csilla-biro-...
#LMBNews

Join the LMB's PhD programme! Applications now open for October 2026 Deadline 2nd December 2025

Want to join the LMB as a PhD student in October 2026?
You’ve got two weeks left to apply!
Visit our website for more details: www2.mrc-lmb.cam.ac.uk/students/int...
Applications close on 2nd December 2025.

Don't miss our new video, all about microbial surface layers! ⬇️🧪🔬

How is the integrated stress response terminated?

@annebertolotti.bsky.social’s group have revealed the mechanism of termination of the ISR, answering a decades-old question surrounding the ISR pathway, which is crucial to cellular homeostasis.
www2.mrc-lmb.cam.ac.uk/how-is-the-i...

#LMBReserch

Join the LMB's PhD programme! Applications now open for October 2026 Deadline 2nd December 2025

Considering the LMB for your PhD?
We’ve got over 25 projects available, covering a wide array of topics. Check them out here: www2.mrc-lmb.cam.ac.uk/students/int...
Apply by 2nd DEC for Autumn 2026 admission.

Black and white photo of James Watson

James (Jim) Watson, LMB Nobel laureate, co-discoverer with Francis Crick of the structure of DNA, has died at the age of 97.
www2.mrc-lmb.cam.ac.uk/james-watson...
#LMBNews #LMBAlumni

Terrific day @mrclmb.bsky.social - tea, lovely homemade cakes, chats with young and old, signed and sold all the copies of my book (32! should have brought more) and had a lovely time giving a talk about Francis Crick. Thanks to all, especially Shahana Ahmed who organised it all and made the cakes!

The Cambridge Biomedical Campus Open Mic returns! With a fully stocked bar and food on sale, whether you’re performing or just soaking up the atmosphere, everyone is welcome – you don’t need to work at the Biomedical Campus to join in!

Find out more: cambridge-biomedical.com/event/open-m...

Excellent #postdoc opportunity available in @sjorsscheres.bsky.social’ group, working on new image processing algorithms for #cryoEM structure determination in their #RELION open-source software.
www.nature.com/naturecareer...
Apply by 25 NOV
#PostdocJobs #ScienceJobs

LMB microscopy activity “Beauty is in the detail”

LMB scientists showcased their research at the @pborostemfest.bsky.social with hands-on activities focused on the microscopic world 🔬

Read about the event here: www2.mrc-lmb.cam.ac.uk/peterborough... #LMBNews

#PeterboroughSTEMFestival

Next Generation Biophysics Symposium 2025 - YouTube The Next Generation Biophysics Symposium is an annual event, organised by MRC LMB, AstraZeneca, Imperial College London and MRC LMS examining the application...

Missed the 2025 Next Generation Biophysics Symposium?
Great news – you can now watch the fantastic talks on our YouTube channel!
www.youtube.com/playlist?lis...

Don't miss these great discussions on how new and emerging technologies may be able to address challenging biological questions.

Linnean Society Fellowship for Caius academic Dr Arun Prasad Pandurangan, a Gonville & Caius College Teaching Associate, has been elected as a Fellow of the Linnean Society of London. The election recognises his significant contributions to struc...

Congratulations to #LMBAlumni Arun Prasad Pandurangan who has been elected a Fellow of the Linnean Society of London in recognition of his work in structural bioinformatics and protein evolution and function!
Read more: www.cai.cam.ac.uk/news/linnean...

In Memoriam: William Scott The longtime professor of chemistry and biochemistry is remembered by family, friends, and colleagues for his immense intellect, generosity, and contributions to advance scientific research

The LMB was saddened to hear of the death of #LMBAlumni Bill Scott, who was a postdoc at the LMB working with Aaron Klug from 1993-1996. During this time he won the LMB’s postdoctoral prize for outstanding research.
Read more about Bill from @ucsantacruz.bsky.social: news.ucsc.edu/2025/10/in-m...

Large group of people gathered together at the LMB

25 years on from publishing the structure of the bacterial 30S ribosomal subunit, alumni, collaborators & friends of Venki Ramakrishnan’s group joined us for a symposium celebrating the legacy of this work.

Read about the event and find photos here: www2.mrc-lmb.cam.ac.uk/25-years-of-...

#LMBNews

M4S collage with past winners and in action pictures

The M4S Competition has expanded its reach to Birmingham and Manchester, underscoring the programme's success in sparking scientific curiosity among primary students across the UK
#LMBNews
www2.mrc-lmb.cam.ac.uk/m4s-expansio...
@mcrcnews.bsky.social @uom-dcs.bsky.social @unibirmingham.bsky.social

David Klenerman University of Cambridge How the physical sciences can empower biology: Applications of single molecule fluorescence to the biosciences Monday 3rd November at 11am (GMT)

Join us at 11am (GMT) on Monday 3rd November to hear about ‘How the physical sciences can empower biology’ from David Klenerman, University of Cambridge.
Find more information here: www2.mrc-lmb.cam.ac.uk/news-and-eve...

LMB prize winners with certificates in the Max Perutz Lecture Theatre with clapping audience

Congratulations to the 2025 recipients of the Eileen Southgate Staff Prize which recognises those who have made outstanding contributions to the LMB: Ian Elbrow, Pam Gallacher, Jessica McCool and Alison Turnock.

Read more about their work here: www2.mrc-lmb.cam.ac.uk/lmb-prizes-2...

#LMBNews 👏

LMB prize winners with certificates in the Max Perutz Lecture Theatre with clapping audience

Congratulations to the 2025 recipients of the Perutz Student Prize and the Joan Steitz Postdoc Prize: Claudia De Miguel, @lucaschwarz.bsky.social, Tom Dendooven, Sofia Lövestam, Katerina Naydenva & Tomke Stürner.

Find out why they won here: www2.mrc-lmb.cam.ac.uk/lmb-prizes-2...

#LMBNews 👏

White mouse in a cardboard tube

Following the Home Office’s report issuing the 2024 animal research statistics, we’ve shared our annual statistics on the use of animals in research.
See our #AnimalStats here: www2.mrc-lmb.cam.ac.uk/research/ani...
@animalresearch.bsky.social #ConcordatOpenness

Chris Russo and Anastasiia Gusach have developed a new method to prepare #cryoEM samples that avoids protein damage during freezing

Read more: www2.mrc-lmb.cam.ac.uk/a-new-method...

#LMBResearch