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A note on the appearance of PEG in macromolecular crystals The use of polyethylene glycol in the crystallization of biological macromolecules and its appearance in the resulting crystals is discussed.

Alexander McPherson: A note on the appearance of PEG in macromolecular crystals #PolyethyleneGlycol #Mechanism #Crystallization @UCIrvine...#IUCr https://journals.iucr.org/paper?S2053230X2501043X

50th anniversary of the Stanford SSRL synchrotron radiation and protein crystallography initiative We provide a historical introduction and our thoughts on the current trends including some based on papers in this special issue of Journal of Synchrotron Radiation celebrating the 50th Anniversary of the Stanford SSRL synchrotron radiation and protein crystallography initiative led by Keith Hodgson.

John R. Helliwell et al.: 50th anniversary of the Stanford SSRL synchrotron radiation and protein crystallography initiative #SynchrotronRadiationAndXFELs @OfficialUoM@DiamondLightSou@CHESS_user...#IUCr https://journals.iucr.org/paper?S1600577525002917

Synchrotron structural biology at SSRL, the beginning and beyond It has been 50 years since the publication in PNAS of our first results on the utilization and demonstrated benefits of synchrotron radiation for macromolecular crystallography. In this brief article, I offer some personal observations and comments about that early research at Stanford and the Stanford Synchrotron Radiation Project (SSRP, later renamed SSRL), how it evolved, and consider key factors in how and why synchrotron radiation ultimately catalyzed a new and transformational paradigm for study of the structure of biomolecules.

Keith Hodgson: Synchrotron structural biology at SSRL, the beginning and beyond #PioneeringSynchrotronStructuralBiology #SSRL #MacromolecularCrystallography @Stanford...#IUCr https://journals.iucr.org/paper?S160057752500788X

Coming soon:-

Synchrotron light: a physics journey from laboratory to cosmos Published in Crystallography Reviews (Ahead of Print, 2025)

New book 📖 review of 'Synchrotron light: a physics journey from laboratory to cosmos' now online - looks an amazing topic!

www.tandfonline.com/doi/abs/10.1...

New for the ESRF User Meeting 2026: early-career travel grants will be available to selected PhD students and post-docs.
Apply now until 7 December!
www.esrf.fr/home/events/...

Acta Cryst. Section B: Structural Science, Crystal Engineering and Materials is pleased to announce the commissioning of a Special Issue dedicated to Crystal Growth and Related Characterization. This follows the introduction of the journal’s Crystal Growth section in 2021 and reflects our continued commitment to advancing research in this area. We invite researchers to contribute original work on all aspects of crystal growth involving non-biological small molecules and extended organic, inorganic or hybrid materials. Topics of interest include, but are not limited to: • Crystal growth mechanisms • Melting, sublimation, and dissolution behavior • Control of morphology, size, and polymorphism • Intermolecular interactions and the assembly of extended structures • Structural characterization via diffraction or atomic-scale imaging • Growth techniques accompanied by a clear crystallographic or structural analysis Submission deadline: 15 December 2025 All manuscripts will undergo standard peer review. Edited by Matias Velazquez (SIMaP, France), Geetha Balakrishnan (University of Warwick, UK) and Tatyana Bekker (Novosibirsk State University, Russia) The Special Issue will be published as a virtual collection on 30 April 2026.

📣 Call for Papers: Special Issue on Crystal Growth & Related Characterization in Acta Crystallographica Section B.
Building on the launch of our Crystal Growth section in 2021, we continue to advance research in this key area.
Submission deadline: 15 Dec 2025.
Submit at: journals.iucr.org/b/

GOLD protein-ligand docking.

We are delighted to be a partner from day 1 with the HelixAI life science AI platform, embedding GOLD in agentic research pipelines, enabling wider adoption across multidisciplinary teams.

🔗 ccdc-info.com/48kqUfk

#DrugDiscovery #DrugDesign

Join the LMB's PhD programme! Applications now open for October 2026 Deadline 2nd December 2025

Want to join the LMB as a PhD student in October 2026?
You’ve got two weeks left to apply!
Visit our website for more details: www2.mrc-lmb.cam.ac.uk/students/int...
Applications close on 2nd December 2025.

Children’s book in front of plant. Book looks like a composition notebook with red title „X-ray crystallography adventures!“ subtitle: cat & elephant‘s sugar crystal mystery. Two cartoons of a cat in a lab coat and an elephant in baking gear are on bottom right.

Thrilled to announce publication of the crystallography children’s book illustrated by undergraduate Justine Wong!

You can buy it here for $15: meitneriumpress.com

50% of profits will support undergrad education at the Cal Poly Pomona Crystallography Co-op.

#chemsky #chemchat

Registration and abstract submission for the BCA Spring Meeting 2026 (30th March-1st April) is live! Deadline for submission is 9am, 19th January.

hg3.co.uk/bca/

BCA BSG Winter Meeting 2025!

Theme: "New Advances and Future Directions in Structural Biology"

🗓️ 12th Dec 2025, University of Oxford

Poster session + prizes! (Talk deadline: 28th Nov)

​Register:
www.oxforduniversitystores.co.uk/product-cata...

​#StructuralBiology #bsgwinter2025 #Crystallography

Hey users!
The ESRF User Meeting 2026 is back!
And registration is now open⬇️

www.esrf.fr/UM2026

Recent advances in pharmaceutical cocrystal design: leveraging in-silico technologies for enhanced drug development Pharmaceutical cocrystals are a versatile means of enhancing the properties of drug compounds, making them a valuable asset in drug formulation and development. They can improve the therapeutic per...

🚨 New review online - Pagare et al 'Recent advances in pharmaceutical cocrystal design: leveraging in-silico technologies for enhanced drug development' 💊⚗️
www.tandfonline.com/doi/full/10....

Find our current issue at this link www.tandfonline.com/toc/gcry20/c... - great landing page for topical reviews of #Crystallography topics

🎉 Proud to highlight core philosophy: To serve, to educate, to enable! Sharing crystallography and education resources at the HMS Core Facilities Poster Showcase.
👉 corefacilities.hms.harvard.edu/2025-harvard... 😀
#Crystallography #Education #Research #CoreFacilities

My author copies have arrived! @iucrjournals.bsky.social

Typewritten transcript of letter from Perutz to Watson describing their early friendship in 51-53 and Perutz's recent work on Huntington's disease as well as his imminent demise.

The things you find in your photo roll #2. For some reason, in August 2013 I took a picture of this charming letter from Max Perutz to Jim Watson, written shortly before Max died.

Home | Program in Molecular Biophysics The Program in Molecular Biophysics (PMB) trains PhD students to do cutting-edge biophysics research using the methods of biology, biochemistry, chemistry, physics, engineering, and computer science.

Apply now to join the Johns Hopkins Program in Molecular Biophysics! Our interdisciplinary Ph.D. program trains students to explore the physical principles underlying biology — from molecules to cells. Open to both U.S. and international applicants. Application deadline Dec. 1 : pmb.jhu.edu

samples of collected data

Celebrate the power of scientific data at IUCr!
CommDat symposia will explore integrative structural chemistry and biology; best practices for data processing; global open science; and ML for materials development
Join us in Calgary:
event.fourwaves.com/...

It has arrived, the 50th anniversary of the seminal synchrotron radiation protein crystallography experiments at SSRL Stanford led by Keith Hodgson. His article also includes his today and the future perspectives @jsynchrotronrad.iucr.org

Journal of Synchrotron Radiation welcomes seven new Co-editors The newest seven members of the Editorial Board of Journal of Synchrotron Radiation are introduced.

Bhattacharyya, Kvashnina and Yabashi: Journal of Synchrotron Radiation welcomes seven new Co-editors #CoEditors #SynchrotronRadiation #FreeElectronLasers @fz_juelich@EuropeanXFEL@desy@esrfsynchrotron@postech2020...#IUCr https://journals.iucr.org/paper?S1600577525009361

Deadline: 4 November!

The ESRF User Organisation invites nominations for the 2026 Young Scientist Award.

If you know an outstanding young scientist who deserves recognition for her/his work at the ESRF — now is the time!
Deadline: 4 November 2025
More information: lnkd.in/dxjn8qqY

Next @IUCrData Raw Data Letter coming soon:-

Proof of kids book in front of plant. Book looks like a composition notebook with red title „X-ray crystallography adventures!“ subtitle: cat & elephant‘s sugar crystal mystery. Two cartoons of a cat in a lab coat and an elephant in baking gear are on bottom right.

Excited to have proofs in hand of our crystallography children‘s book! Illustrated by an amazing undergrad Justine Wong!

More info coming soon…
#chemsky

Solving molecular organic crystal structures from powders Powder diffraction is a widespread technique found in academic, forensic, industrial research and quality-control laboratories the world over. The recent article by Kabova et al. [(2025), Acta Cryst. C81, 559–569] provides step-by-step guidance on how to proceed and the software the authors use, from sample preparation and the powder diffraction measurement itself, to the verification of the final structure.

Andrew N. Fitch: Solving molecular organic crystal structures from powders #PowderXRayDiffraction #RealSpaceStructureSolution #OrganicMolecules ... #IUCr https://journals.iucr.org/paper?S2053229625009052

Another fabulous IUCr Newsletter:-

Structures of photoactive yellow protein were determined by serial femtosecond crystallography after illumination, capturing the isomerization of the chromophore after it absorbs light. Structures included in this movie include: 5hd3 (ground state), 5hdc (100-400 femtoseconds after illumination), 5hdd, 5hds (3 picoseconds), 4b9o (100 picoseconds), 5hd5 (200 nanoseconds) and 1ts0 (1 millisecond). For more, see the Molecule of the Month on Photoactive Yellow Protein and Guide to Understanding PDB Data: Methods for Determining Atomic Structures.

Interested in Synchrotrons & XFEL Radiation?
The IUCr2026 meeting has you covered with SEVEN sessions, including Synergies between cryoEM, diffraction methods, and complementary biophysical measurements; Structural studies across time scales; and more:
event.fourwaves.com/...

Robert Huber: ‘I call the last century the century of vision’ The Nobel laureate on the joys of entering a developing field, and the century of vision

Very nice interview. I heard Robert Huber lecture many times. In Trieste at a conference we shared breakfast together and of course discussing our field.
Robert Huber: ‘I call the last century the century of vision’
www.chemistryworld.com/opinion/robe...

💠 The ACA community mourns the loss of Dr. Benno P. Schoenborn (1938–2025), a pioneer in neutron protein crystallography whose work transformed structural biology.
Read more and share memories: 🔗 bit.ly/42wNvlM
#crystallography #InMemoriam #ACACommunity #neutrondiffraction