Chrystal Starbird's Avatar

Chrystal Starbird

@drstarbird.bsky.social

Scientist, mother, perpetual learner. Assistant Professor, Structural Biologist, Advocate, and Speaker. Views my own. signal @starbic.01 www.starbirdlab.com

7,219 Followers  |  604 Following  |  1,141 Posts  |  Joined: 04.09.2023  |  2.1818

Latest posts by drstarbird.bsky.social on Bluesky

01.02.2026 22:07 β€” πŸ‘ 57    πŸ” 11    πŸ’¬ 0    πŸ“Œ 0
A pile of valentines, including a gulper eel saying "you make my jaw drop", a grimalditeuthis saying "I find you a-LURE-ing" a whale skeleton at the bottom of the ocean with snailfish and two octopuses making heart arms under the words "I've whale-fallen for you", and an anglerfish saying "You're my light in the darkness", and then two packs of cards that are all nice and tied up

A pile of valentines, including a gulper eel saying "you make my jaw drop", a grimalditeuthis saying "I find you a-LURE-ing" a whale skeleton at the bottom of the ocean with snailfish and two octopuses making heart arms under the words "I've whale-fallen for you", and an anglerfish saying "You're my light in the darkness", and then two packs of cards that are all nice and tied up

Hey cuties. Everything sucks ass. Get some valentines and send them to your friends.

I'm sad. You're sad. They're probably sad.

Send them a valentine.

It keeps Skype a Scientist running, which hey, is very good too.

squidfacts.bigcartel.com/product/deep...

28.01.2026 15:58 β€” πŸ‘ 388    πŸ” 197    πŸ’¬ 11    πŸ“Œ 17
Trump slump? Attendance plummets at some science meetings, but others hold steady Amid travel bans, a government shutdown, and funding crunches, 2025 was a turbulent year for U.S. scientific societies

New article on the impact of the past year on conference attendance and scientific societies.

As I mentioned, I had a great experience at many of the meetings I attended, though I know some attendance numbers were down and societies continue to need our support.

www.science.org/content/arti...

30.01.2026 21:02 β€” πŸ‘ 4    πŸ” 5    πŸ’¬ 0    πŸ“Œ 0

I know we have more important things to focus on, like ensuring the safety of many, but…

I couldn’t resist posting this for those scientists who still insist this is like 2008 and will just blow over. This is only one sector of scientists. It’s well past time to stop pretending it’s all ok.

29.01.2026 20:42 β€” πŸ‘ 7    πŸ” 4    πŸ’¬ 0    πŸ“Œ 0

As you should be! πŸŽ‰

29.01.2026 16:25 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Tumor Microenvironment Meeting Promo
YouTube video by KeystoneSymposia Tumor Microenvironment Meeting Promo

⏰ Submit short talk abstracts and/or scholarship apps by Feb 4 at 11:59 PM for the Symposium on Tumor Microenvironment.

🎀 Speaker preview: youtu.be/lyK8XkYC8cI
πŸ”— Apply: keysym.us/KSTumorMicro26

@coussenslab.bsky.social @sandramcallister.bsky.social @laurakiessling.bsky.social

#KSTumorMicro26

29.01.2026 15:09 β€” πŸ‘ 4    πŸ” 3    πŸ’¬ 0    πŸ“Œ 0

HUGE Congratulations to the Mudumbi Lab!!! πŸŽ‰πŸ‘‡πŸΎ

29.01.2026 13:04 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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Yum!

26.01.2026 02:25 β€” πŸ‘ 4    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

One of my favorites! A true trailblazer!

26.01.2026 02:24 β€” πŸ‘ 8    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Thank you @keystonesymposia.bsky.social for another great Advisory Board meeting! Being a Keystone Fellow was a highlight of my faculty career and I suggest anyone eligible apply!

26.01.2026 01:02 β€” πŸ‘ 4    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0

Yeah, the family at home said it was sleeting again a while ago. I hope we can get home tomorrow! 🀞🏾

26.01.2026 00:02 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Statement from the family of Alex Pretti, Michael and Susan Pretti:
We are heartbroken but also very angry.
Alex was a kindhearted soul who cared deeply for his family and friends and also the American veterans whom he cared for as an ICU nurse at the Minneapolis VA hospital. Alex wanted to make a difference in this world.
Unfortunately he will not be with us to see his impact. I do not throw around the hero term lightly. However his last thought and act was to protect a woman.
The sickening lies told about our son by the administration are reprehensible and disgusting. Alex is clearly not holding a gun when attacked by Trump's murdering and cowardly ICE thugs. He has his phone in his right hand and his empty left hand is raised above his head while trying to protect the woman ICE just pushed down all while being pepper sprayed.
Please get the truth out about our son. He was a good man. Thank you.

Statement from the family of Alex Pretti, Michael and Susan Pretti: We are heartbroken but also very angry. Alex was a kindhearted soul who cared deeply for his family and friends and also the American veterans whom he cared for as an ICU nurse at the Minneapolis VA hospital. Alex wanted to make a difference in this world. Unfortunately he will not be with us to see his impact. I do not throw around the hero term lightly. However his last thought and act was to protect a woman. The sickening lies told about our son by the administration are reprehensible and disgusting. Alex is clearly not holding a gun when attacked by Trump's murdering and cowardly ICE thugs. He has his phone in his right hand and his empty left hand is raised above his head while trying to protect the woman ICE just pushed down all while being pepper sprayed. Please get the truth out about our son. He was a good man. Thank you.

Statement from the family of Alex Pretti.

25.01.2026 19:46 β€” πŸ‘ 1411    πŸ” 360    πŸ’¬ 6    πŸ“Œ 6
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Me and my oldest deep in the Colorado mountains 😁

25.01.2026 20:10 β€” πŸ‘ 11    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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The work portion of the trip is over and my flight was canceled, so going exploring! 😁

25.01.2026 18:20 β€” πŸ‘ 6    πŸ” 2    πŸ’¬ 1    πŸ“Œ 0
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Minnesota’s justice system will have the last word.

24.01.2026 22:06 β€” πŸ‘ 10531    πŸ” 2625    πŸ’¬ 701    πŸ“Œ 144
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a woman singing into a microphone with the words livin ' on the edge written below her ALT: a woman singing into a microphone with the words livin ' on the edge written below her

Is it crazy to be flying out today with the impending Snowmaggedon. Probably.

23.01.2026 11:07 β€” πŸ‘ 4    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Sequence-encoded differences in the conformational ensembles of CITED transcriptional activation domains impact coactivator binding Recent advances in predicting and modeling conformational ensembles of intrinsically disordered proteins (IDPs) have provided much needed insights into sequence-ensemble relationships. It is thought that conservation of physicochemical properties, but not the exact identity or order of the amino acids, maintains IDP ensemble properties that are crucial for function. However, detailed experimental studies are still required to fully understand the relationships between sequence and function in IDPs. The human CITED proteins, which are fully disordered transcriptional regulators, share conserved C-terminal transactivation domains (CTADs) that interact with the TAZ1 domain of the transcriptional coactivators CBP/p300. The conserved CTADs harbor amino acid substitutions in regions that are known to be important for interactions of CITED2 with TAZ1, but the effects of these substitutions on TAZ1 binding for the other CITED proteins are unknown. Here, we use solution NMR spectroscopy, circular dichroism, and surface plasmon resonance to characterize the conformational ensembles, dynamics, and interactions of the CITED CTADs. The CTADs are disordered in isolation, although the CITED2 CTAD uniquely displays residual helical structure that is sensitive to ionic strength and protein concentration. In contrast, the CITED1 and CITED4 CTADs remain largely disordered and exhibit more uniform dynamics. Quantitative binding measurements reveal differences in thermodynamics and kinetics for the CTADs' interactions with TAZ1, with CITED2 binding most tightly and CITED4 exhibiting significantly weaker affinity. Our results highlight the sensitivity of IDP conformational ensembles to minor sequence changes and the impacts that changes in IDP structures and dynamics can have on biological functions. ### Competing Interest Statement The authors have declared no competing interest. National Cancer Institute, https://ror.org/040gcmg81, P30CA016086 National Institute of General Medical Sciences, https://ror.org/04q48ey07, P41GM111135

So excited to see this preprint up from my colleague @berlowlab.bsky.social and team! Very cool work on how differences in sequence encode for changes in the conformational ensembles adopted by human CITED proteins! Congrats!!! πŸŽ‰

www.biorxiv.org/content/10.6...

21.01.2026 14:38 β€” πŸ‘ 2    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0

Thank you!!!

21.01.2026 12:04 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Thank you!!! 😊

21.01.2026 12:04 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Thank you!!!

21.01.2026 12:04 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Thank you!!

21.01.2026 12:04 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Thank you! πŸ™πŸΎ

21.01.2026 12:04 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Honored and Thankful! πŸ™πŸΎ #MLKDay

21.01.2026 00:21 β€” πŸ‘ 23    πŸ” 3    πŸ’¬ 5    πŸ“Œ 0

This is the kind of story that makes me miss Twitter back in the day.

Glad everyone got out safe and I’m sure everyone’s rushing to travel with them again 😬

20.01.2026 13:04 β€” πŸ‘ 4    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Watching this closely because I’m supposed to fly on Friday and return Sunday for a meeting 😬

19.01.2026 21:04 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

β€œI believe that unarmed truth and unconditional love will have the final word in reality. This is why right, temporarily defeated, is stronger than evil triumphant.”

A quote from Martin Luther King, Jr. that I wanted to share today. Optimism is hard some days, but this reflects a belief I share

19.01.2026 16:54 β€” πŸ‘ 18    πŸ” 8    πŸ’¬ 0    πŸ“Œ 0
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If you are local, please attend the MLK Ceremony next week. I’m very honored to be nominated by students and receiving one of the β€œUnsung Hero” awards at this ceremony!

13.01.2026 19:21 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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The NIH has lost its scientific integrity. So we left β€œWe can no longer lend our credibility to an organization that has lost its integrity,” write four scientists and administrators who recently resigned from the NIH.

Powerful piece in STAT this morning from some NIH staff members who have resigned

www.statnews.com/2026/01/10/n...

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10.01.2026 12:24 β€” πŸ‘ 523    πŸ” 268    πŸ’¬ 9    πŸ“Œ 18
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Conquer Your Fellowship: A Project Management Tool and Guide for Your NIH Fellowship Applying for an NIH fellowship can feel overwhelming, but the right guidance makes all the difference. This collection of resources walks you through every stage of the process – from identifying t…

πŸ“’ Planning to apply for an NIH F30, F31, or F32 fellowship? The process can feel overwhelming, but BRET has some helpful resources to guide you through the process and apply by the April 8 deadline! medschool.vanderbilt.edu/career-devel...

08.01.2026 17:15 β€” πŸ‘ 3    πŸ” 2    πŸ’¬ 1    πŸ“Œ 0

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