Chris W Whelan's Avatar

Chris W Whelan

@cwhelan.bsky.social

Genomics and bioinformatics. Computational Biologist at Broad Institute. Dad. Bostonian.

350 Followers  |  397 Following  |  8 Posts  |  Joined: 20.09.2023  |  1.4226

Latest posts by cwhelan.bsky.social on Bluesky

The current admissions system based on SES zones and bonus points excludes many kids with A grades and high test scores, especially those from Catholic schools like yours. If we are going to stick with that system then increasing the number of seats seems like the right thing to do to me.

14.05.2025 16:57 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

If this happens, this policy change will prevent discoveries and will result in our children and grandchildren being sicker and dying sooner

07.02.2025 23:48 β€” πŸ‘ 48    πŸ” 13    πŸ’¬ 2    πŸ“Œ 4

ATTENTION

If you are someone who had an F31-Diversity (or similar) application submitted this cycle, please DM me here, contact me on signal (jeremymberg.78), or email me at jeremymberg@gmail.com.

I will keep all information confidential.

2/n

07.02.2025 16:06 β€” πŸ‘ 195    πŸ” 270    πŸ’¬ 8    πŸ“Œ 11

If doing CNV calling the default bin size in GATK gCNV for Illumina data is 1kb. I’d look at the histogram and MAD of 1kb bin depths. If its not tight or your regions of interest contain lots of repetitive sequence 5 or 10kb might work (with less resolution)

04.01.2025 14:44 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Not window size based, but we often use metrics like β€œPercent bases at 20X coverage” to QC WGS data for variant calling.

04.01.2025 14:24 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

I'm sort of skeptical that that's the case at selective schools, which in my experience liked well-rounded applicants, but maybe things have changed.

11.12.2024 17:45 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Genuine question -- why not just push for rigorous college-prep level high school humanities classes then? I confess I do not get the appeal of Early College as currently presented. Seems like quasi-vocational "career-track" stuff instead of a chance to actually explore college-level classes early.

11.12.2024 14:59 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

What Wu policies are responsible for the low homicide rate?

11.12.2024 14:49 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Today is the FINAL day to submit your bids in our Silent Auction for a Healthy Ocean!

Bidding closes at 8 PM Eastern! Jenna and Sarah will be going LIVE on Instagram at 4 PM to showcase some of the incredible auction itemsβ€”tune in to catch the action! ow.ly/5vVf50UkggC

03.12.2024 19:03 β€” πŸ‘ 2    πŸ” 3    πŸ’¬ 2    πŸ“Œ 0

I put some #rstats code into Claude and told it to optimize it. It totally rewrote it and got a 50x speed up with identical results. …maybe we actually are cooked?

03.12.2024 21:00 β€” πŸ‘ 4    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Lifelong JP resident. BPS grad and (unhappy) BPS parent.

19.11.2024 14:06 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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As part of #gnomAD v4, in collaboration with the Talkowski Lab, we have released 1,199,117 genome SVs and 66,903 rare exome CNVs. These data represent the first gnomAD SV dataset released native to the GRCh38 reference genome. (1/2)

02.11.2023 12:58 β€” πŸ‘ 7    πŸ” 3    πŸ’¬ 1    πŸ“Œ 0
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The #gnomAD team is proud to announce the release of gnomAD v4! The v4 dataset includes 730,947 exomes & 76,215 genomes, which is ~5x larger than the v2 & v3 releases combined, & includes nearly 120K indivs of non-European genetic ancestry broad.io/gnomad #ASHG23 (1/11)

01.11.2023 18:35 β€” πŸ‘ 32    πŸ” 21    πŸ’¬ 2    πŸ“Œ 2

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