Christos Constantinidis's Avatar

Christos Constantinidis

@cconstan.bsky.social

Professor of Biomedical Engineering and Neuroscience. Neural basis of cognition, cognitive development, deep brain stimulation. https://lab.vanderbilt.edu/constantinidis-lab/home/

2,170 Followers  |  1,055 Following  |  175 Posts  |  Joined: 21.01.2024  |  1.7498

Latest posts by cconstan.bsky.social on Bluesky

NOT-OD-26-019: Updated Application Policies: NIH Administrative Burden Reduction Effort Removal of Requirements for Letters of Intent and Unsolicited Applications Requesting $500,000 or More in Dire... NIH Funding Opportunities and Notices in the NIH Guide for Grants and Contracts: Updated Application Policies: NIH Administrative Burden Reduction Effort Removal of Requirements for Letters of Inten...

For you NIH folks, two interesting announcements. 1) no more LOIs. 2) No more needing permission to apply with a budget of over $500K per year. grants.nih.gov/grants/guide...

06.12.2025 19:23 β€” πŸ‘ 5    πŸ” 5    πŸ’¬ 0    πŸ“Œ 1
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How distributed is the brain-wide network that is recruited for cognition? - Nature Reviews Neuroscience Both localized and distributed views on the functional organization of the brain have been put forward. In this Perspective, Rosen and Freedman examine the degree to which these two views account for ...

Thoughtful review with some good recent historical perspective on the ongoing paradigm shift that is radically changing the way we think about what brain areas do.

www.nature.com/articles/s41...

04.12.2025 17:56 β€” πŸ‘ 91    πŸ” 38    πŸ’¬ 2    πŸ“Œ 2
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Sensory reformatting for a working visual memory A core function of visual working memory (WM) is to sustain mental representations of recent visual inputs, thereby bridging moments of experience. This is thought to occur in part by recruiting early...

new paper in TICS officially out today. great learning from and writing with Anastasia, and super cool cover art from Prof. Pinar Yoldas.
www.cell.com/trends/cogni...

04.12.2025 01:21 β€” πŸ‘ 70    πŸ” 34    πŸ’¬ 1    πŸ“Œ 1
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High-frequency bursts facilitate fast communication for human spatial attention - Nature Neuroscience Using intracranial electroencephalography from patients with epilepsy during spatial attention tasks, this study shows that high-frequency bursts facilitate fast communications in brain networks and s...

Our new paper is out in @natneuro.nature.com

How do large-scale brain networks route information about where/what to attend at fast timescales?

High-frequency bursts facilitate fast communication for human spatial attention

www.nature.com/articles/s41...

03.12.2025 22:02 β€” πŸ‘ 13    πŸ” 4    πŸ’¬ 1    πŸ“Œ 0
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Americans’ Social Media Use 2025 YouTube remains the most popular, but adults are increasingly using Instagram, TikTok, WhatsApp and Reddit. Use of some platforms varies by age, gender, and race and ethnicity.

Bluesky running neck and neck with truth social

www.pewresearch.org/internet/202...

03.12.2025 03:14 β€” πŸ‘ 4    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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The U.S. Is Funding Fewer Grants in Every Area of Science and Medicine A quiet policy change means the government is making fewer bets on long-term science.

Very sad analysis of the science funding situation in the US right now

www.nytimes.com/interactive/...

02.12.2025 12:46 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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NIH shake-up to grant decision-making draws concerns of political meddling Policy drops β€œpaylines” based on peer-review scores and requires geography and other factors to guide approvals

NIH shake-up to grant decision-making draws concerns of political meddling | Science | AAAS www.science.org/content/arti...

25.11.2025 18:26 β€” πŸ‘ 7    πŸ” 6    πŸ’¬ 0    πŸ“Œ 0

For the first time ever, I had to make a payment in crypto.

I can now confidently say that crypto payments combine the speed of a dial up modem and the ease of updating the drivers on a 1998 HP Laserjet printer.

18.11.2025 05:58 β€” πŸ‘ 1525    πŸ” 214    πŸ’¬ 45    πŸ“Œ 16
NOT-OD-26-005: Interim Guidance on Reopening of NIH Extramural Activities NIH Funding Opportunities and Notices in the NIH Guide for Grants and Contracts: Interim Guidance on Reopening of NIH Extramural Activities NOT-OD-26-005. NIH

October and November NIH grant submission deadlines will be extended.

Study sections scheduled between October 1 and November 14 have been cancelled and will be rescheduled.

grants.nih.gov/grants/guide...

16.11.2025 13:36 β€” πŸ‘ 3    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0

I got a similar message. My study section is being rescheduled for 2 partial days in January. Only 1/3 of grants will be discussed.

14.11.2025 03:49 β€” πŸ‘ 7    πŸ” 5    πŸ’¬ 0    πŸ“Œ 0

Is there a competition going on about who is going to screw science the most?

14.11.2025 03:46 β€” πŸ‘ 3    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Without monkeys, neuroscience has no future Research in primate brains has been essential for the development of BCIs, ANNs. New funding and policy changes put future such advances at risk.

Research in primate brains has been essential for the development of brain-computer interfaces and artificial neural networks. New funding and policy changes put future such advances at risk, write Cory Miller, @movshon.bsky.social and Doris Tsao.

#neuroskyence

bit.ly/47MXYLH

10.11.2025 14:56 β€” πŸ‘ 56    πŸ” 31    πŸ’¬ 1    πŸ“Œ 5
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White matter connections may drive adolescent cognitive gains, study suggests Adolescence, the life stage that marks the transition between childhood and adulthood, is known to be a vital period for the brain's development. During this critical phase, people's mental abilities,...

A very nice summary of our article

medicalxpress.com/news/2025-11...

10.11.2025 14:06 β€” πŸ‘ 5    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Postdoc Position: Neural Circuitry Underlying Working Memory | Radboud University Do you want to work as a Postdoc Position: Neural Circuitry Underlying Working Memory at the Faculty of Social Sciences? Check our vacancy!

🚨🧠🚨 POSTDOC POSITION 🚨🧠🚨 in my lab: www.ru.nl/en/working-a... Connectivity in Working Memory. Deadline 12 Nov! Apply via website; please repost.

09.11.2025 09:17 β€” πŸ‘ 37    πŸ” 38    πŸ’¬ 1    πŸ“Œ 0

Who did this?

07.11.2025 15:35 β€” πŸ‘ 3    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
A hilariously inaccurate "diagram" of visual areas of the brain created by Chat GPT

A hilariously inaccurate "diagram" of visual areas of the brain created by Chat GPT

generating examples for my fall undergrad Perception students on why they should not use LLMs as study aides...

15.08.2025 16:12 β€” πŸ‘ 217    πŸ” 52    πŸ’¬ 13    πŸ“Œ 8
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Longitudinal measures of monkey brain structure and activity through adolescence predict cognitive maturation - Nature Neuroscience Working memory improves during adolescent brain development. Zhu et al. tracked monkeys through adolescence, revealing that maturation of white matter tracts and refinement of neural firing patterns s...

Longitudinal measures of monkey brain structure and activity through adolescence predict cognitive maturation

@cconstan.bsky.social

www.nature.com/articles/s41...

06.11.2025 19:52 β€” πŸ‘ 15    πŸ” 4    πŸ’¬ 0    πŸ“Œ 0
8 snippets showing 5 seconds of intracranial oscillatory brain activity from an electrodes located in the temporal cortex. brain plot showing the location of the electrode + surrounding electrodes.

8 snippets showing 5 seconds of intracranial oscillatory brain activity from an electrodes located in the temporal cortex. brain plot showing the location of the electrode + surrounding electrodes.

auditory tau-rhythm with a cool waveform, oscillating at 10 Hz, recorded with intracranial electrodes. πŸ§ γ€°οΈπŸ™‚

06.11.2025 13:29 β€” πŸ‘ 24    πŸ” 3    πŸ’¬ 2    πŸ“Œ 0
Associate Professor & Director of NCBG Herbarium This is a research, teaching, and public service position at the University of North Carolina at Chapel Hill, serving jointly as Herbarium Director at the North Carolina Botanical Garden (NCBG) and as...

The 5th of 6 faculty positions in UNC Biology is posted. We're working with the @ncbg.bsky.social to fill a joint position as Director of the UNC Herbarium at @ncbg.bsky.social and as Associate Professor within the Department of Biology (BIOL). Please share 1/n
unc.peopleadmin.com/postings/308...

06.11.2025 11:36 β€” πŸ‘ 38    πŸ” 38    πŸ’¬ 1    πŸ“Œ 2

Ok Mamdani won. Can we now reopen the government, please?

05.11.2025 12:51 β€” πŸ‘ 5    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Cover of β€œ233 Celsius” by Ray Bradbury

Cover of β€œ233 Celsius” by Ray Bradbury

The first (1955) Danish edition of Ray Bradbury’s FAHRENHEIT 451. Later editions did not convert the title, so this is the only SI-compatible edition! 🎒

01.11.2025 19:55 β€” πŸ‘ 1937    πŸ” 497    πŸ’¬ 30    πŸ“Œ 49

A sad day for Neuroscience in the Netherlands.

30.10.2025 23:56 β€” πŸ‘ 15    πŸ” 5    πŸ’¬ 0    πŸ“Œ 0

Many thanks to the interdisciplinary team that made this study possible - and to my trainees Junda Zhu and Clement Garin who saw it to completion (10/10)

27.10.2025 13:28 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Because rhesus macaque brain development parallels human trajectories, these findings illuminate mechanisms of adolescent cognition and why connectivity disruptions may underlie psychiatric risk (9/10)

27.10.2025 13:28 β€” πŸ‘ 3    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

Long-distance tracts, including the superior fronto-occipital fasciculus and anterior cingulum, best predicted working memory precision and speed (8/10)

27.10.2025 13:28 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

Unlike prior emphasis on gray matter thinning (e.g. due to pruning of unwanted synapses), our study shows cortical volume & thickness poorly predict cognitive maturation. White matter maturation was the key driver (7/10)

27.10.2025 13:28 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

Prefrontal neuron firing rate generally increased through adolescence, while variability declined, and dimensionality of responses increased, supporting flexible coding and distractor resistance (6/10)

27.10.2025 13:28 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

Tracking monkeys from late childhood to adulthood, we combined behavior, MRI, and single-neuron recordings. Our overarching result was that working memory improved as frontal lobe structural connectivity strengthened (5/10)

27.10.2025 13:28 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

However the brain alterations responsible for the changes in neural firing rate, which is ultimately altering the maturing cognitive functions, have remained elusive (4/10)

27.10.2025 13:28 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

It has been well known that improvement of cognitive performance in adolescence coincides with a number of structural changes in the brain, including volume and surface of the prefrontal cortex and maturation of white matter tracts (3/10)

27.10.2025 13:28 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

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