Isaac Paddy

Prof. Laura Dassama (Stanford Chem) is developing a small-molecule therapy for sickle cell disease that removes BCL11A, restoring fetal hemoglobin without gene editing. Her goal is a simpler, more affordable sickle cell therapy. brnw.ch/21wXP8k

Congratulations to 2025 #MacFellow William Tarpeh! The Stanford chemical engineer is working on sustainable and practical solutions to treat wastewater and recover valuable mineral resources.

🗞️: stanford.io/3IZIBqF

Thank you!!

So honored to be a part of this years HHMI Gilliam Fellows cohort! Thankful for my amazing mentor @lmkdassama.bsky.social and all of those who’ve supported me. Excited to join the community!

Truly thrilled that @isaacapaddy.bsky.social has been named a Gilliam Fellow!! Isaac is a model trainee and has been a delight to work with. Many congratulations, Isaac! We found out during our weekly individual meeting that he would be a Gilliam Fellow, and I happened to capture the moment 🤗.

Truly wonderful to celebrate these amazing scientists graduating from the Dassama group! Congrats to @mekedlawitts.bsky.social @jonathanccc-chem.bsky.social on their PhDs and to Sebastian Alfonso on his Masters, all in Chemistry! @stanfordchemistry.bsky.social @stanford-chemh.bsky.social

Engineering Cell-Specific Protein Delivery Vehicles for Erythroid Lineage Cells Biologics such as proteins, peptides, and oligonucleotides are powerful ligands to modulate challenging drug targets that lack readily accessible and “ligandable” pockets. However, the limited membran...

Delighted to share this work led by @mekedlawitts.bsky.social that investigates the delivery efficiency of various protein delivery vehicles! pubs.acs.org/doi/10.1021/...

Everything feels weird and uncertain, and I can only imagine how trainees feel right now… so are some things mentors can do to support mentees during these challenging times: 🧵

Identifying Opportunity Targets in Gram-Negative Pathogens for Infectious Disease Mitigation Antimicrobial drug resistance (AMR) is a pressing global human health challenge. Humans face one of their grandest challenges as climate change expands the habitat of vectors that bear human pathogens...

Delighted to share this Outlook that @isaacapaddy.bsky.social and I worked on, now out in ACS Central Science! In this forward-thinking piece and call-to-action, we try to identify "druggable" points of vulnerability in non-model pathogenic bacteria! pubs.acs.org/doi/10.1021/...

Introducing Dr. @jonathanccc-chem.bsky.social, the first PhD from the Dassama Lab! I am very proud of the broad and deep undertakings that formed Jonathan's thesis! Some highlights are in the comments. Many congrats to the doc!!