Jacob Nadel

Go Gaby!!! The superest star!!! @glopez.bsky.social

dopamine sometimes tell you nopamine?

every college, corporate, and nonprofit president right now

Test effects of behavior/events at every trial timepoint in photometry analyses! Paper with Erjia Cui, Dave Lovinger, Francisco Pereira. “A Statistical Framework for Analysis of Trial-Level Temporal Dynamics in Fiber Photometry Experiments.” Python+R packages! elifesciences.org/articles/95802. 1/13

Awesome work from an amazing set of labs and institution!

Rats and mice rapidly update timed behaviors - Animal Cognition Keeping track of time intervals is a crucial aspect of behavior and cognition. Many theoretical models of how the brain times behavior make predictions for steady-state performance of well-learned int...

How quickly can rodents adapt to changes in time durations in their environment? Work from @oberlincollege.bsky.social suggests they can recognize and respond extremely quickly, hinting at a rapid mechanism for learning about time in the brain. link.springer.com/article/10.1...

My feed is overwhelmed with scientists right now calling out the catastrophic consequences of the NIH indirect cost order from last night. If those same people aren't also speaking out against the anti-trans, anti-DEI, anti-immigrant orders...we are lost. The only path forward is solidarity.

Indirect Costs at NIH . . . I wasn’t planning on spending part of a Saturday writing about cost accounting principles and the like, but NIH-world was hit with a doozy of a policy announcement on Friday night:

Great analysis of the indirect cost rate announcement by @stuartbuck.bsky.social

Honored to receive first place poster award at #wcbr2025! Thanks to all who stopped by. The poster (and my panel) explored divergent signaling dynamics in VTA dopamine subpopulations, as well as functional roles for glutamate and dopamine in co-transmitting VTA neurons. Stay tuned for more!

Had SUCH an amazing time at my first #wcbr — so grateful for the opportunity! It was so great to see friends new and old. Hope to be in #Bigsky next year!

Hi #ACNP2024! I'm a postdoc in Reesha Patel's lab at Northwestern, and this is my first in-person ACNP 🎉

I'm presenting a poster on Monday (M157) on VTA 🌟astrocyte 🌟 activity during appetitive and aversive conditioning!

Big Supreme Court argument today regarding the right of trans kids to get proper medical care. This matters. Diminishing the rights of one group diminishes the rights of all us.

#transrightsmatter

Very excited for this! Sign up, it’s free and online!

The Anti-Trans Athlete Panic is a jobs program for the world’s shittiest athletes.

Gotta risk it for the biscuit

Neuronal heterogeneity in the ventral tegmental area: distinct contributions to reward circuitry and motivated behavior The ventral tegmental area (VTA) is a critical component of brain reward circuitry that influences motivation, learning, and emotional regulation. Alt…

Excited to see this review manuscript from lab MD/PhD student Dalton Fitzgerald officially out in Addiction Neuroscience!
www.sciencedirect.com/science/arti...

#BlackInNeuro Starter Pack v1! Let us know if we missed you. #BlackInSTEM #Neuroscience 🧪

go.bsky.app/F8PpdPe

Ketone ester–enriched diet ameliorates motor and dopamine release deficits in MitoPark mice MitoPark mice, a model of Parkinson's disease, fed a ketone ester–enriched diet had moderate improvements in locomotor performance on open field and rotarod behavioural tasks. This behavioural improv....

My main postbac project is published! In collaboration with the late great Richard Veech, we tested how ketone-ester enriched chow impacted the progression of motor and dopamine deficits in the MitoPark mouse model. Find out more here! doi.org/10.1111/ejn....

Nadel: it’s bedtime