Junghee Lee

#JNeurosci | Turrini et al. explore how different brain regions communicate with each other to support automatic imitative behavior in people. https://doi.org/10.1523/JNEUROSCI.0340-25.2025

Volume 51 Issue Supplement_3 | Schizophrenia Bulletin | Oxford Academic The flagship journal of the Schizophrenia Bulletin family. Reviews recent developments and empirically based hypotheses regarding the etiology and treatment of schizophrenia, ranging from the molecula...

ICHR special issue in Schizophrenia Bulletin released this month. Too many good papers to mention - academic.oup.com/schizophreni...

Statistical evidence in psychological networks - Nature Human Behaviour Psychometric network models have become increasingly popular in psychology and the social sciences. Huth et al. show that a large proportion of reported network findings are based on weak or inconclusive evidence inviting caution when interpreting results.

Psychometric network models have become increasingly popular in psychology and the social sciences. Huth et al. show that many reported network findings are based on weak or inconclusive evidence inviting caution when interpreting results.

Pre- and post-decision signals of certainty in changing minds In a recent study, Goueytes and colleagues combined computational modeling with intracranial recordings to dissect the neural basis of confidence and changes of mind. They reveal a temporally organize...

Our spotlight article on Goueytes et al. (2025) study is now online at Trends in Neurosciences: "Pre- and post-decision signals of certainty in changing minds", by P. Barttfeld, @ncomay.bsky.social, I. Embon & @guillermosolovey.bsky.social www.cell.com/trends/neuro...

Age‐Associated Inflammatory Monocytes Are Increased in Menopausal Females and Reversed by Hormone Replacement Therapy Post-menopausal females (> 64 years) have an increase in frequency of inflammatory monocyte populations with defective phagocytosis as compared to pre-menopausal (< 40 years) females. Hormone Replace....

I am so proud to say that our paper is now available at Aging Cell. There is a paucity of data as to how the menopause impacts your immune system, and the aim of this study was to investigate the impact of the menopause on monocyte phenotype and function.
onlinelibrary.wiley.com/doi/10.1111/...

Cannabis Use Among Individuals With Psychosis After State-Level Commercial Cannabis Legalization This report analyzes changes in cannabis-use patterns associated with recreational cannabis legalization in adults with psychosis.

Cannabis Use Among Individuals With Psychosis After State-Level Commercial Cannabis Legalization url: jamanetwork.com/journals/jam...

Subcortical brain abnormalities and cognitive function in individuals with psychosis and their unaffected relatives: A normative modeling approach Previous research has shown subcortical aberrations in individuals with psychosis (probands) and their unaffected first-degree relatives. However, few…

New work from the lab, led by a wonderful graduate student, Maria Stanica, in collaboration with @ninakraguljac.bsky.social and Scott Sponheim at UMN www.sciencedirect.com/science/arti...

The Content and Topography of Auditory Verbal Hallucinations in Adult Psychosis Patients: What Does a Voice Say, and How Does It Say It? An Umbrella Review and Collation Background Auditory verbal hallucinations (‘voices’) in clinical psychosis are associated with significant distress and disability, but the efficacy of CBT for voices is modest. Greater phenomenolog.....

Umbrella review from Cassie Hazell (a co-founder of ECHR!) and colleagues on what voices (AKA auditory verbal hallcuinations) say and how they say it (e.g., voice frequency, emotional tone, gender, and accent) - onlinelibrary.wiley.com/doi/10.1002/...

Creative hobbies could slow brain ageing at the molecular level To keep the mind young, dance the tango.

The power of tango

www.nature.com/articles/d41...

Modulation of functional network co-activation pattern dynamics following ketamine treatment in major depression Abstract. Ketamine produces fast-acting antidepressant effects in treatment resistant depression (TRD). Prior studies have shown altered functional dynamics between brain networks in major depression. We thus sought to determine whether functional brain network dynamics are modulated by ketamine therapy in TRD. Participants with TRD (n=58, mean age=40.7 years, female=48.3%) completed resting-state fMRI scans and clinical assessments (mood and rumination) at baseline and 24 h after receiving four ketamine infusions (0.5mg/kg) over two weeks. Healthy controls (HC) (n=56, mean age=32.8 years, female=57.1%) received the same assessments at baseline and after two weeks in a subsample without treatment. A co-activation pattern (CAP) analysis identified recurring patterns of brain activity across all subjects using k-means clustering. Statistical analyses compared CAP metrics including the fraction of time (FT) spent in a brain state, and the transition probability (TP) from one state to another over time and associations with clinical improvement. Follow-up analyses compared HC and TRD at baseline. Six brain state clusters were identified, including patterns resembling the salience (SN), central executive (CEN), visual (VN), default mode (DMN), and somatomotor (SMN) networks. Following ketamine, TRD patients showed decreased FT for the VN (p=7.4E-04) and increased FT for the CEN state (p=1.9E-03). For TP metrics, SN-CEN increased (p=5.8E-04) and SN-VN decreased (p=3.6E-03). Decreased FT for the SN associated with improved rumination (p=1.9E-03). At baseline, lower FT for CEN (p=5.70E-04) and TP for SN-CEN (p=0.016) and higher TP for SN-VN (p=2.60E-03) distinguished TRD from HCs. CAP metrics remained stable over time in a subsample of HCs (n=18). These findings suggest ketamine modulates brain network dynamics between SN, CEN and VN in TRD, which may normalize dynamic patterns seen in TRD at baseline towards patterns seen in controls. Changes in SN state dynamics may correspond to improvements in ruminative symptoms following ketamine therapy.

New from Brandon Taraku 🧠: Modulation of functional network co-activation pattern dynamics following ketamine treatment in major depression url: direct.mit.edu/imag/article...

Different exploration strategies along the autism spectrum: diverging effects of autism diagnosis and autism traits - Molecular Autism When faced with many options to choose from, humans typically need to explore the utility of new choice options. People with an autism diagnosis or elevated autism traits are thought to avoid exploring such unknown options, but it remains unclear how autism affects exploration in decision spaces with many options. In a large online sample (N = 588), we investigated the impact of autism diagnosis or elevated autism traits on exploration behavior during value-based decision-making in vast decision spaces. We used a 121-armed bandit with spatially correlated choice options, and a dedicated computational model to disentangle generalization, uncertainty-guided exploration, and random exploration strategies. Our findings show that participants with a self-reported autism diagnosis were less likely to explore novel choice options and more likely to exploit known high-value options. Computational modeling suggests they engaged in less uncertainty-driven exploration but exhibited equal random exploration and generalization strategies. Interestingly, among non-diagnosed participants, people with elevated autism traits did not explore less. This study relies on self-reported autism diagnoses and trait measures collected online. This may limit the generalizability of the findings to clinically verified or more diverse autism populations. Our findings highlight important differences in exploration strategies between clinical and subclinical populations and emphasize the importance of cognitive modeling and using vast decision spaces to better understand autism.

"neither autism nor autism traits lead to suboptimal... decision-making" & "autism leads to less exploration while more autism traits did not (or even to more exploration)" molecularautism.biomedcentral.com/articles/10.... "results caution against extrapolating findings from trait studies to autism"

The Circle Continues - Charles M. Schulz Museum At the Charles M. Schulz Museum and Research Center, we often hear questions like, “What research is done here?” or, “What is the research about?”. Our answer is that the […]

The question was "What do you think makes a good citizen?”.

schulzmuseum.org/the-circle-c...

JAMA graphs show childhood insurance dynamics. Graph A: Medicaid/CHIP coverage vs. age. "Ever in Medicaid" peaks at 61%. Graph B: Uninsurance vs. age. "Ever uninsured" reaches 42%, while "Always uninsured" is 0%. Published Sept 24, 2025.

An estimated 61% of U.S. children have been enrolled in #Medicaid or CHIP and 42% have experienced periods of uninsurance by age 18, with insurance disruptions being more common in states with restrictive Medicaid policies.

ja.ma/474AItj

The social, decoupled self: interpersonal synchronization of breathing alters intrapersonal cardiorespiratory coupling People synchronize their periodic behavioural and physiological rhythms with each other during social interaction. While this interpersonal synchronization has largely been associated with positive ef...

🫁❤️New preprint out: The social, decoupled self

We show effects of interpersonal synchronization of physiological rhythms on intrapersonal cardiorespiratory coupling: when we sync our breathing, our breathing–heart rhythms decouple, with a perturbed phase-relationship
www.biorxiv.org/content/10.1...

Rewards bias self-evaluations of ability - Communications Psychology People often receive rewards for good performance, but what happens when rewards do not reflect ability? Two behavioral studies suggest that rewards can impact how we evaluate our own ability, above and beyond the impact of actual performance.

Very excited to share that my first paper, with Peter Mende-Siedlecki and @leorhackel.bsky.social, is out now in @commspsychol.nature.com! ☺️

Can getting more rewards make you feel more skilled, even if your performance doesn't change?

www.nature.com/articles/s44...

How to Think, Not What to Think College is not just about transmitting knowledge—it’s also about learning and practicing the skills that connect us to one another.

What I need to remind myself everyday: how to think and how to communicate

www.theatlantic.com/ideas/archiv...

Pre-stimulus beta power mediates explicit and implicit perceptual biases in distinct cortical areas - Communications Psychology Two EEG studies in healthy human adults suggest that choice history and stimulus probability-induced biases in somatosensory perception are reflected in distinct prestimulus beta power modulations across distinct cortical regions.

Pre-stimulus beta power mediates explicit and implicit perceptual biases in distinct cortical areas
www.nature.com/articles/s44...
#neuroscience

We are hiring a new Director for our Psychosis Program. Come join us at the University of Illinois at Chicago. The opportunities are endless... Job postings below:

uic.csod.com/ux/ats/caree...

When we hear about a lone scientist who made groundbreaking discoveries on their own, it’s usually erasing the truth that science is a team sport, and field research builds on the local knowledge and expertise of the people that live there (8/10)

New layer-fMRI preprint using simultaneous layer-fMRI with EEG at 7T. Establishing an acquisition and analysis setup to capture layer-fMRI correlates of spontaneous alpha power variations.
By Marsh et al.
doi.org/10.1101/2025...

Internal uncertainty impacts social information use in risky choice across adolescence - Communications Psychology Adolescents’ choices are influenced by others. A social risky choice experiment and Bayesian modelling reveal that age differences in internal uncertainty, being unsure how to choose, relate to differences in susceptibility to social influence.

😍 Our latest is out now in @commspsychol.nature.com. 🤩 We show with Bayesian modelling and experimental manipulation of uncertainty that developmental differences in social influence depend on differences in the internal uncertainty people have about their choice
doi.org/10.1038/s442...

From a poster called “just shower thoughts“ reading: when people talk about traveling to the past, they worry about radically, changing the present by doing something small, barely anyone in the present to really thinks that they can radically change the future by doing something small.

I may have found my defining quote.

Pair this with my pinned post and you will see what I mean!

(PDF) The duration of affective phenomena or emotions, sentiments and passions PDF | On Jan 1, 1991, Nico H. Frijda and others published The duration of affective phenomena or emotions, sentiments and passions | Find, read and cite all the research you need on ResearchGate

study emotion? sections of this are a v worthwhile read. no paywall. useful reminder that not everyone falls neatly into BET v constructionism buckets researchgate.net/publication/255522683_The_duration_of_affective_phenomena_or_emotions_sentiments_and_passions

Title: Understanding Brain-Body Interactions to Advance Brain Health: A Workshop. Photo: picture of a transparent person with brain and nervous system illuminated.

Save the date 📆. On Oct 22/23, @nationalacademies.org will hold a stellar virtual workshop on brain/body interations (open to all).

www.nationalacademies.org/en/our-work/...

Really enjoyed my weekend read on 𝐚𝐜𝐭𝐢𝐯𝐞 𝐟𝐢𝐥𝐭𝐞𝐫𝐢𝐧𝐠: local recurrence amplifies natural input patterns and suppresses stray activity. This review beautifully argues that sensory cortex itself is a site of memory and prediction. Food for thought on hallucinations!

#neuroskyence #neuroscience

Synchrony and symphony by Flavio Frohlich #SRP2025

Wonderful talk on brain dynamics by Scott Sponheim, SRP President #SRP2025

Back to LA for #SRP2025!!

psychopathology.org/annual-meeti...

We should!

How does the brain fill in what's missing?

Pattern completion pushes visual cortex into "seeing" what is not there. Great to see this out, congrats to the authors on this impressive work!

#neuroskyence