Junghee Lee

Viewpoint: Achieving viral suppression in #HIV treatment prevents #AIDS progression, requiring age-sensitive care to manage aging and multimorbidity in those with HIV.

ja.ma/3UHFKVB #MedSky

Remission in Individuals With Clinical High Risk for Psychosis This cohort study compares incidence, prevalence, and stability of remission, and associations with clinical and demographic factors among individuals at clinical high risk (CHR) for psychosis using 2...

prevalence and stability of remission
jamanetwork.com/journals/jam...

Sankey diagram showing analysis steps for fNIRS. Snakes flow from left to right showing different design choices that many teams made during data analysis. Overall it looks like sort of a mess.

38 research teams analyzed the same fNIRS data...Really nice visualization of the variety of processing pipelines people use from Meryem Yücel, Rob Luke, et al.:

"fNIRS reproducibility varies with data quality, analysis pipelines, and researcher experience"

www.nature.com/articles/s42...

Addressing artifactual bias in large, automated MRI analyses of brain development - Nature Neuroscience As large-scale neurodevelopmental MRI studies gain prominence, the authors identify tradeoffs between sample size and quality control that can dramatically affect results, and they evaluate a range of...

www.nature.com/articles/s41...

Structured vs Self-Guided Multidomain Lifestyle Interventions for Global Cognitive Function This randomized clinical trial assesses the effect of structured vs self-guided multidomain lifestyle interventions on changes in global cognitive function over 2 years among older adults at risk of c...

A self-guided intervention worked quite well. It will be important to learn more about the durability of these effects.
jamanetwork.com/journals/jam...

The title & table of contents for the latest volume of the Advances in Experimental Social Psychology (2025, Volume 72) for the chapter by Michael Inzlicht, Aidan V. Campbell, & Blair Saunders, entitled "Effort paradox redux: Rethinking how effort shapes social behaviors" (pp. 1-55).

The abstract of the Inzlicht, Campbell, & Saunders (2025) chapter, entitled "Rethinking how effort shapes social behavior."

This new AESP chapter piqued my interest. As someone studying procrastination, I can see why effort is avoided (e.g., part of task aversion) & is also valued (e.g., deep satisfaction, work ethic). I look forward to taking a deep dive & gaining new insights into the role of effort in procrastination.

Attractor dynamics of working memory explain a concurrent evolution of stimulus-specific and decision-consistent biases in visual estimation People exhibit biases when perceiving features of the world, shaped by both external stimuli and prior decisions. By tracking behavioral, neural, and mechanistic markers of stimulus- and decision-related biases, Gu et al. show that working memory’s attractor dynamics—instantaneously updated by decisions—comprehensively explain the growth and interplay of these biases.

Online now:

Altered processing of self-produced sensations in psychosis at cortical and spinal levels Molecular Psychiatry - Altered processing of self-produced sensations in psychosis at cortical and spinal levels

just out in Molecular Psychiatry 😍: spinal & cortical alterations in processing of self-produced sensations in psychosis

including: touch, interoception, fMRI, SEP, HEP, behavior🧠🫀

#neuroskyence
#PsychSciSky
@paulasalamone.bsky.social @adamenmalm.bsky.social @rkaldewaij.bsky.social
rdcu.be/exN0e

How did newspapers in places like Harrisburg, Birmingham, and Syracuse become some of America’s most-read online? They share an owner that sometimes gets forgotten — but which dominates much larger peers in web traffic. Here's our first monthly ranking of the top 25 local newspaper websites in the United States.

New feature alert @niemanlab.org: Traffic rankings for the top U.S. news outlets in three categories — local newspapers, nonprofit news sites, and public radio stations. First up, local newspapers

by @joshuabenton.com

Mary Had Schizophrenia—Then Suddenly She Didn’t Some psychiatric patients may actually have treatable autoimmune conditions. But what happens to the newly sane?

A woman diagnosed with schizophrenia was ill for two decades—then suddenly she wasn’t. Rachel Aviv reports on the connection between autoimmune disorders and psychiatric conditions.

title of the manuscripts published today

What happens when you compare brain scans from people before and after the pandemic started?
A new study released today with 996 participants shows the pandemic accelerated brain aging for all, but those infected with COVID also presented reduced cognitive performance. #NeuroCovid #LongCovid

Any time a paper reports an AUC of 1.0 on test data, my hackles are raised. This commentary by @olegolt.bsky.social @tspisak.bsky.social @christianbuchel.bsky.social nicely dissects problems with a recently reported "biomarker" for pain.

Auditory illusory models as proxies to investigate bottom-up and top-down neural networks of phantom perception Abstract. Auditory phantom perception, exemplified by tinnitus, is characterized by a perceptual experience without external stimuli. This study utilized two auditory illusions, the Zwicker Tone (ZT) ...

Inverse relationship between parietal theta power and strength of pavlovian hallucinations - very cool!

direct.mit.edu/imag/article...

Great & important work. That said, one area that is still overlooked is data quality. This is harder to model because contrast-to-noise can be application specific, but it's critical when designing large studies. Better data means similar results with smaller N or shorter scans. 1/2

Distinct prelimbic cortex neuronal responses to emotional states of others drive emotion recognition in adult mice Jabarin et al. show that adult mice recognize emotional states of others in a sex-specific manner. Emotion recognition is driven by the differential response of prelimbic cortex pyramidal neurons to a...

Folks, the video abstract on this paper is a masterpiece

www.cell.com/current-biol...

H/t Urszula Skupio

‘The damage is terrifying’: Barbara Kingsolver on Trump, rural America and the recovery home funded by her hit novel Demon Copperhead, the author’s retelling of Dickens during Virginia’s opioid crisis, was a global success. Now she has used royalties from the novel to open a recovery residence

Novelist Barbara Kingsolver has given much of her income away, including spending proceeds from Demon Copperhead on a recovery home for those affected by the opioid epidemic: “Material success came gradually. So I had time to learn how to draw a cap on what we need & what we can do with the rest”

Resilient cortical maps - Nature Neuroscience Despite the loss of neurons during aging and the early stages of neurodegenerative disease, many cortical brain functions remain remarkably intact. Although this resilience is traditionally attributed...

Homeostasis can keep population-level responses stable in the face of neural drift and "vanishing neurons"

Nice write up of a paper I'm looking forward to reading but that seems to add more wood to the "populations are more than the sum of their neurons" fire

www.nature.com/articles/s41...

The cultural construction of “executive function” | PNAS In cognitive science, the term “executive function” (EF) refers to universal features of the mind. Yet, almost all results described as measuring E...

www.pnas.org/doi/10.1073/...

Experimentology cover: title and curves for distributions.

Experimentology is out today!!! A group of us wrote a free online textbook for experimental methods, available at experimentology.io - the idea was to integrate open science into all aspects of the experimental workflow from planning to design, analysis, and writing.

Feudalism Is Our Future What the next Dark Ages could look like

"There is no "must" in history"
www.theatlantic.com/magazine/arc...

Altered neural oscillations are associated with improved working memory performance in schizophrenia following D-cycloserine administration
doi.org/10.1016/j.sc...
#neuroscience

Selective insensitivity to global vs. local linguistic context in speech produced by patients with untreated psychosis and positive thought disorder Early psychopathologists proposed that certain features of positive thought disorder, the disorganized language output produced by some people with sc…

a wonderful example of how to use large language models in clinical research www.sciencedirect.com/science/arti...

Pro tip, folks: if you make a figure for a publication, don’t just hand the copyright over to the publisher. Post it on OSF first and then give yourself permission to use it in the first publication and then all future publications. That way, no permissions issues.

Attacks on science are attacks on making and keeping America great: op-ed "Our American scientific engine ... is good for the economy, it improves lives, and it’s one of the true wonders of the world."

Neuroscientist Kristina Visscher writes, “I’m reaching out to you as a nerdy kid from Northport, Alabama, who – thanks to a great Alabama public education – got a Ph.D. in Neuroscience” @visscherlab.bsky.social
www.al.com/news/2025/06...

An Uproar at the NIH Jay Bhattacharya, the the agency’s director, has made a point of welcoming dissent. A letter from his officials will test that.

www.theatlantic.com/health/archi...

New NIH Notice rescinding the no DEI, no Israeli boycott term and condition added to NIH grants (covers the whole university)

This is what Williams refused to sign and declined all federal funding.

grants.nih.gov/grants/guide...

1/2

A neural basis for distinguishing imagination from reality Dijkstra et al. show that our brain distinguishes imagination from reality by monitoring how strongly the fusiform gyrus is activated. When imagined and real images produce similar activity, people can confuse them. This helps explain how we normally tell what is real—and why that sometimes fails.

Online now:

Exclusive: US veterans agency orders scientists not to publish in journals without clearance Move that seeks political control of doctors’ and scientists’ published research fits a pattern of censorship by the Trump administration, veterans advocates say

"Senior officials at the US Department of Veterans Affairs have ordered that VA physicians and scientists not publish in medical journals or speak with the public without first seeking clearance from political appointees of Donald Trump, the Guardian has learned."

Distinct structural deficits in treatment-resistant schizophrenia and their putative neurotransmitter basis: a source-based morphometry analysis - Neuropsychopharmacology Neuropsychopharmacology - Distinct structural deficits in treatment-resistant schizophrenia and their putative neurotransmitter basis: a source-based morphometry analysis

www.nature.com/articles/s41...

People with schizophrenia that is resistant to treatment may have specific prefrontal-limbic brain deficits linked to non-dopaminergic neurotransmitter systems—highlighting the need for therapies beyond antipsychotics. #schizophrenia #neuroscience #mentalhealth

At Chapel Hill, Only Health-Sciences Professors Have Been Getting Tenure The UNC Chapel Hill board hasn’t tenured a single professor in fields outside the health sciences since January. The inaction has prompted confusion and alarm among faculty.

This is the first media coverage that I have seen of the UNC board's quiet decision to largely pause granting tenure outside of the health sciences. This is worth watching over the coming weeks.