Schizophrenia International Research Society (SIRS)

Congratulations to Dr. Catalina Mourgues-Codern, recipient of the 2025 SIRS Research Harmonisation Award! 🌟

Read More: schizophreniaresearchsociety.org/research-har...

Please join us in celebrating Dr. Mourgues-Codern's achievement! 🎉

#SIRS2025 #SchizophreniaResearch

🌍 This Mental Illness Awareness Week, we recognize the strength of the global mental health community: researchers, clinicians, advocates, and those with lived experience.

SIRS is proud to be part of this effort, advancing understanding and innovation in schizophrenia research. 💙

#MIAW #SIRS

⏳ One Week Left! Submit for the SIRS Research Fund Award by 9 October 2025.

This award supports early career investigators in launching innovative projects to advance understanding, prevention, and treatment of schizophrenia.

🔗 Learn More: schizophreniaresearchsociety.org/join/researc...

📢 SIRS 2026 Annual Congress Registration is Now Open! 🎉

Join us 25–29 March 2026 in Florence, Italy for groundbreaking science, collaboration, and progress in schizophrenia research.

🔗 Learn More: schizophreniaresearchsociety.org/meetings/gen...

🔗 Register Today: sirs.societyconference.com/v2/

📖 A New Chapter for Schizophrenia

Thank you to Dr. Robin Emsley for 3.5 years of leadership as Editor. Welcome Dr. Anthony A. Grace, Distinguished Professor and global leader in schizophrenia research, as our new Editor.

Please join us in celebrating this transition!💫
#SIRS #SchizophreniaResearch

📢 SIRS 2026 Annual Congress Registration Opens in 5 Days! 📆

Join us 25–29 March 2026 in Florence, Italy for groundbreaking science, collaboration, and progress in schizophrenia research.

🔗 Learn More: schizophreniaresearchsociety.org/meetings/gen...

#SIRS2026

✨ Open Submissions for #SIRS2026! ✨

SIRS is accepting submissions for the 2026 Annual Congress
📍 Florence, Italy | 25–29 March

📅 Mark your calendar and submit today: schizophreniaresearchsociety.org/meetings/awa...

🌍 Why join SIRS? 🌍

Membership connects you to a global network advancing schizophrenia research & treatment — with benefits like journal access, reduced congress fees, early-publication emails, networking, & more.

✨ Learn more: schizophreniaresearchsociety.org/join/why-join/

#SIRS #Membership

How does attachment affect help-seeking in people with paranoia and psychosis? The role of emotion regulation, self-stigma, and perceived support Longer duration of untreated psychosis causes significant human and healthcare costs. Attachment avoidance and anxiety contribute to delays in help-se…

🧩 Why do people with paranoia & #psychosis delay help-seeking? Study finds attachment avoidance & anxiety reduce help-seeking/acceptance.

Mediators: 🚫 self-stigma & 🤝 perceived support.

Published in Schizophrenia Research.🔗 doi.org/10.1016/j.sc...

Shape the future of #schizophrenia research today! Submit your Symposium Proposal before 23 October and join us in Florence, Italy for the 2026 Annual Congress, March 25–29. sirs.societyconference.com/v2/ #SIRS2026

Danish nationwide study (birth cohorts 1990–1999) shows neighborhood deprivation independently raises #schizophrenia risk. Read more here: www.sciencedirect.com/science/arti...

👥 Nearly 45% of caregivers of people with #schizophrenia in China report social isolation. Read more here: www.sciencedirect.com/science/arti...

Interpretable LLM–Based Detection of Loose Associations Using Synthetic Speech Data in Early Psychosis AbstractBackground and Hypothesis. Loose Associations (LA) in speech are key indicators of psychosis risk, notably in schizophrenia. Current detection meth

Incorporating Large Language Models (LLMs) in machine learning protocols improved detection of loose associations in early psychosis speech data. There is potential for LLMs to help identify subtle thought disorders for early intervention. Link: doi.org/10.1093/schb... #LLMs #EarlyPsychosis #SIRS

Effect of social resources on readmission prevention and the influence of informal coercion in acute schizophrenia: a retrospective quasi-experimental cohort study During hospitalization, social resources are introduced with or without informal coercion as means of supporting the life of people with acute schizop…

Linking patients with social resources can help prevent readmission in acute schizophrenia, but coerced provision nullifies this benefit. Professionals should avoid informal coercion and instead foster patient motivation when connecting to support services. Link: doi.org/10.1016/j.sc...

⏰ The deadline for Honorific Award nominations is approaching! Don’t miss your chance to recognize outstanding contributions in schizophrenia research. Submit today and join us in Florence, Italy for the 2026 Annual Congress, March 25–29. sirs.societyconference.com/v2/ #SIRS2026

This article considers ethical issues in recruiting patients with treatment-resistant psychotic symptoms. Cognitive impairment, rather than severity of psychopathology, appears to be the greatest challenge to decisional capacity. Link: doi.org/10.1093/schi...
#Ethics #TreatmentResistance #Capacity

Today is World Suicide Prevention Day. Suicide is a leading cause of premature mortality in people with schizophrenia and other serious mental illnesses. Research and compassion are key to reducing risk and supporting recovery. Together, we can help save lives. 💙 #WorldSuicidePreventionDay

Individuals with schizophrenia have lower life expectancies by 15–20 years compared to the general population. Use of second-generation antipsychotics & low-frequency hospitalization were significantly associated with reduced all-cause & cause-specific mortality. Link: doi.org/10.1038/s415... #SIRS

Longitudinal changes in striatocortical connectivity in first-episode psychosis associated with the emergence of treatment resistance - Schizophrenia Schizophrenia - Longitudinal changes in striatocortical connectivity in first-episode psychosis associated with the emergence of treatment resistance

New study found longitudinal changes in striatocortical connectivity in first-episode psychosis associated with the emergence of treatment resistance. @sirsofficial.bsky.social bit.ly/3JHvj26

📆 September is here! Your SIRS Submission Deadlines are Approaching FAST!

Be Part of the Conversation in Florence, Italy
Submit Your Symposia Proposal Today!

#SIRS2026

LINK: sirs.societyconference.com/v2/#card/sub...

In observance of Labor Day, our office will be closed on Monday, September 1st. We will resume regular business hours on Tuesday, September 2nd We wish you a wonderful holiday weekend.

Individuals w/ affective psychosis show reduced posterior hippocampal volume, unlike anterior-first pattern seen in non-affective psychosis
A higher prevalence of incomplete hippocampal inversion (IHI) in both psychosis groups, suggests shared neurodevelopmental vulnerability
doi.org/10.1016/j.sc...

New Findings on Trauma & Psychosis
A large-scale longitudinal study w/ Adverse Childhood Experiences (ACEs) predict poorer social functioning & higher levels of depression, anxiety, & substance misuse over 1 year
Highlights trauma-informed care in the treatment of psychosis
doi.org/10.1016/j.sc...

Central Obesity-related Brain Alterations Predict Cognitive Impairments in First Episode of Psychosis AbstractBackground and Hypothesis. Cognitive impairment is a key contributor to disability and poor outcomes in schizophrenia, yet it is not adequately add

New research links central obesity to brain aging & cognitive decline in early psychosis
In first-episode schizophrenia, higher waist-to-hip ratio predicted older “brain age” & worse verbal learning
Targeting obesity may help protect brain & cognition
academic.oup.com/schizophreni... #obesity

Using Electronic Health Records to Identify Medical Presentation for Self-harm as a Predictor of Psychotic or Bipolar Disorders: A Systems-level Alternative to the Clinical High-risk Approach AbstractBackground and Hypothesis. We examined associations between medical presentation for self-harm and subsequent diagnosis of a psychotic or bipolar d

Research by Cooper et al show that youth presenting with self-harm in medical settings are at significantly higher risk of later developing psychotic or bipolar disorders. In the US, risk is especially high after ER/hospital visits (nearly 20%)
🌟Early intervention is critical
doi.org/10.1093/schb...

The second I laid eyes on him…” First impressions strongly influence willingness to engage people w/ schizophrenia
In real-world interactions, they’re often judged more negatively from the start impacting social inclusion #schizophrenia #mentalhealth #stigma #socialpsychology doi.org/10.1016/j.sc...

Elevated neutrophil-to-lymphocyte ratios correlate with increased clozapine concentration-to-dose ratios during titration - Schizophrenia Schizophrenia - Elevated neutrophil-to-lymphocyte ratios correlate with increased clozapine concentration-to-dose ratios during titration

💡 New Findings in Clozapine Pharmacokinetics

🔗 Read the study here: doi.org/10.1038/s415...

#Clozapine #Pharmacokinetics #Inflammation #Schizophrenia

🗽Happy Fourth of July to our members in the USA! Wishing you a joyful and safe Independence Day celebration. Please Note: Our office will be closed on Friday, July 4th, in observance of the holiday. 🎆

Schizophrenia Recovery Book 📘
Written by someone who’s lived it, James McLure shares his powerful journey through schizophrenia & depression in Eight Stones: My Journey Through Schizophrenia and Depression
Transformation, resilience, & hope for anyone facing mental health challenges
👉 a.co/d/a9bX7d2

RHA Submissions DUE 20 June: Only 1 submission per person. The Awardee will be selected by 1st of Aug. A total of $5,000 USD is available to support a research harmonisation group over the two-year period. *Only members of SIRS are eligible to apply. schizophreniaresearchsociety.org/research-har...