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Renee Chang

@reneechang.bsky.social

PhD Candidate in the Kranzusch Lab at Harvard Medical School / studying mechanisms of viral immune evasion

32 Followers  |  17 Following  |  1 Posts  |  Joined: 15.07.2025  |  1.3574

Latest posts by reneechang.bsky.social on Bluesky

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A widespread family of viral sponge proteins reveals specific inhibition of nucleotide signals in anti-phage defense Chang et al. discover anti-CBASS 4 (Acb4), a family of viral sponges that inhibits bacterial immunity by sequestering nucleotide immune signals. Acb4 homologs in phages that infect hosts across all ma...

The beautiful, ever-expanding universe of viral proteins targeting nucleotide immune signals!

Paper by @reneechang.bsky.social in @cp-molcell.bsky.social on a nucleotide sponge www.cell.com/molecular-ce...

and preprint by @doudna-lab.bsky.social on viral nucleases www.biorxiv.org/content/10.1...

22.08.2025 21:02 — 👍 48    🔁 19    💬 0    📌 0
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A widespread family of viral sponge proteins reveals specific inhibition of nucleotide signals in anti-phage defense Chang et al. discover anti-CBASS 4 (Acb4), a family of viral sponges that inhibits bacterial immunity by sequestering nucleotide immune signals. Acb4 homologs in phages that infect hosts across all ma...

Excited to share my PhD work in the @kranzuschlab.bsky.social, out now in Molecular Cell @cp-molcell.bsky.social

We discover Acb4, a new family of viral sponges that sequesters nucleotide immune signals and defines molecular features that enable ligand specificity.

www.cell.com/molecular-ce...

23.08.2025 00:21 — 👍 29    🔁 9    💬 1    📌 0

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