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Luca Laraia

@lucalaraia.bsky.social

Associate Professor, Department of Chemistry, Technical University of Denmark. Chemical biology, medicinal chemistry, everything related to sterols.

1,484 Followers  |  871 Following  |  33 Posts  |  Joined: 18.12.2023  |  1.8817

Latest posts by lucalaraia.bsky.social on Bluesky

Highly recommended PhD position in Copenhagen! Apply now!

10.10.2025 08:24 β€” πŸ‘ 2    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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PhD fellowship in Organic Synthesis and Supramolecular Chemistry The Department of Chemistry at the University of Copenhagen invites applicants for a PhD fellowship in Organic chemistry with a particular focus on supramolecul

I have a fully funded PhD position available in my group in Copenhagen: candidate.hr-manager.net/ApplicationI...

09.10.2025 06:51 β€” πŸ‘ 11    πŸ” 13    πŸ’¬ 0    πŸ“Œ 2

Cool work! I think we should be looking at targeting PH domains more!

07.10.2025 17:20 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

Very exciting work. Shows how interfering with the levels of one lipid class leads to changes of other lipids that are not directly metabolically connected as the cell tries to maintain both lipid flux balance and biophysical membrane properties.

03.10.2025 13:37 β€” πŸ‘ 18    πŸ” 7    πŸ’¬ 1    πŸ“Œ 0
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How do cells sense & respond to lipid imbalances? What happens when a disease-relevant enzyme is blocked? Shiying Huang investigates phosphoinositide lipids with the Balla lab & discovers an integrated cellular response that boosts alternate lipid synthesis pathways! www.biorxiv.org/content/10.1...

03.10.2025 13:03 β€” πŸ‘ 34    πŸ” 13    πŸ’¬ 0    πŸ“Œ 1
Quantitative imaging of species-specific lipid transport in mammalian cells

If you want to do a deep dive into the data – here’s a website where you can browse through all the images, look at every detail and jump right into mass spectrometric lipid flux data:
www.lipidimaging.org

21.08.2025 05:18 β€” πŸ‘ 10    πŸ” 2    πŸ’¬ 1    πŸ“Œ 0

Stunning and hugely influential work - congratulations!

21.08.2025 08:16 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Fantastic work by @nadlerlab.bsky.social and colleagues. A must read for all those interested in lipids and imaging!

21.08.2025 08:16 β€” πŸ‘ 5    πŸ” 2    πŸ’¬ 1    πŸ“Œ 0
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Call for 20 Assistant Professor positions Karolinska Institutet is a world-leading medical university with a long and proud history of ground-breaking research. We are now recruiting outstanding early-career researchers with particularly exce...

Wow

Karolinska Institutet is recruiting 20 outstanding early-career researchers for assistant professor positions

ki.se/en/about-ki/...

25.07.2025 22:29 β€” πŸ‘ 249    πŸ” 195    πŸ’¬ 7    πŸ“Œ 15

To clarify: this is a postdoc position.

23.06.2025 12:53 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Postdoctoral fellowship in protein biochemistry and biophysics - DTU Chemistry Do you want to contribute to an exciting chemical biology project? This postdoctoral fellowship deals with the synthesis of probes aimed at studying cholesterol transport proteins in health and diseas...

I am looking to hire a protein #biochemist, #biophysicist or structural biologist: efzu.fa.em2.oraclecloud.com/hcmUI/Candid...

- 2-year position working on lipid transport proteins.
- Experience in protein expression, purification and biochemical and biophysical assay development.
Please share!

23.06.2025 12:40 β€” πŸ‘ 2    πŸ” 6    πŸ’¬ 1    πŸ“Œ 0

It was a pleasure to present at this fantastic conference! Thanks to @rscmedchem.rsc.org for this great opportunity and the award!

12.06.2025 05:22 β€” πŸ‘ 12    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Thanks George :)

24.05.2025 10:20 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

I will soon be posting a postdoc position in protein biochemistry/biophyics! Interested candidates are welcome to reach out at luclar@kemi.dtu.dk. Experience in protein expression, purification, and assay development is a must. Structural biology would be great! Please RT :)

24.05.2025 08:25 β€” πŸ‘ 2    πŸ” 1    πŸ’¬ 0    πŸ“Œ 1
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Dr. Jeremy Baskin wins the 2024 ACS Chemical Biology Young Investigator Award | ACS Publications Chemistry Blog Get to know more about Dr. Baskin's work and career in this exclusive interview.

It’s an honor to receive the ACS Chem Biol Young Investigator Award! I’m most grateful for the contributions from all past & present lab members β€” it is an award for all of you as much as for me. (& also grateful to still be considered young πŸ˜…) axial.acs.org/chemical-bio...
@acsbiol.bsky.social 1/2

22.03.2025 18:35 β€” πŸ‘ 218    πŸ” 27    πŸ’¬ 37    πŸ“Œ 1

Congratulations!!!

22.03.2025 19:52 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Any1 is a phospholipid scramblase involved in #endosome biogenesis, say Jieqiong Gao, Christian Ungermann and colleagues (OsnabrΓΌck University): rupress.org/jcb/article/...

#Membrane #lipid #Organelles #Biochemistry

13.03.2025 14:38 β€” πŸ‘ 22    πŸ” 8    πŸ’¬ 0    πŸ“Œ 1
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Are lipids actively sorted during clathrin mediated endocytosis like proteins? @mathilda95.bsky.social addresses this key open question together with our collaborators from the Honigmann and Modes labs using a new Lipid-STED workflow.
www.biorxiv.org/content/10.1...

10.03.2025 11:56 β€” πŸ‘ 115    πŸ” 38    πŸ’¬ 2    πŸ“Œ 9

Super interesting - looking forward to reading it in detail!

07.03.2025 07:54 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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🚨New preprint: There's this overlooked phospholipid with 3 acyl tails called NAPE that is made during ischemia. We identified its interactome & found it regulates lactate flux, suggesting metabolic functions in response to hypoxia. Congrats to Dylan Chiu! doi.org/10.26434/che... #lipidtime #chembio

06.03.2025 15:15 β€” πŸ‘ 68    πŸ” 18    πŸ’¬ 4    πŸ“Œ 4
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Join us in Copenhagenfor the European Symposium on organic chemistry this summer: www.esoc2025.com

20.02.2025 08:22 β€” πŸ‘ 19    πŸ” 7    πŸ’¬ 3    πŸ“Œ 0

And if folks think it’s a tough situation with antibacterials, wait until they see what it looks like with antifungals!

18.02.2025 20:26 β€” πŸ‘ 21    πŸ” 4    πŸ’¬ 1    πŸ“Œ 2

We look forward to welcoming you @eortegaforte.bsky.social in our group! Great job putting together the #MSCA application - a very well deserved award!

18.02.2025 14:58 β€” πŸ‘ 3    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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Do you want to present your research to a global audience?

Then you should check out, #RSCPoster, which will happen on March 4th to 5th. Very excited to chair the #ChemBio part #RSCChemBio together with Lyn Jones and Ali Tavassoli.

Click this link for all information: www.rsc.org/our-events/r...

12.02.2025 15:38 β€” πŸ‘ 9    πŸ” 3    πŸ’¬ 1    πŸ“Œ 0
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A potent epigenetic editor targeting human PCSK9 for durable reduction of low-density lipoprotein cholesterol levels - Nature Medicine Epigenetic editing of PCSK9 in the liver, designed to induce DNA methylation and silence gene expression, achieved long-lasting reductions in LDL cholesterol levels in both transgenic mice expressing ...

Most genome editing work to date has been DNA based. A new paper out today assessed a single dose of epigenetic editing (thru PCSK9) for marked (~70%) and durable reduction of LDL cholesterol [in non-human primates]
www.nature.com/articles/s41...

10.02.2025 16:01 β€” πŸ‘ 190    πŸ” 40    πŸ’¬ 8    πŸ“Œ 4
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We are pleased to announce that this year, the International Chemical Biology Society (ICBS) conference in joint with the ECBS (European Chemical Biology Symposium), will be at the Sorbonne UniversitΓ© in Paris, Oct 6 - 9! Stay tuned at: www.chemical-biology.org #chemicalbiology #ICBS2025 #ECBS2025

10.02.2025 13:52 β€” πŸ‘ 24    πŸ” 9    πŸ’¬ 0    πŸ“Œ 0

Ready to take off as a synthetic chemist? Check out this tutorial review we wrote with Frank Glorius and Jasper Tyler!

07.02.2025 18:58 β€” πŸ‘ 29    πŸ” 2    πŸ’¬ 1    πŸ“Œ 0

Thanks George!!

07.02.2025 07:56 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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What's Happening Inside the NIH and NSF

A long post about what’s happening to the science funding agencies in the US and why. As mentioned, this one just kept getting longer even as I kept stripping curse words from it.

www.science.org/content/blog...

04.02.2025 16:40 β€” πŸ‘ 415    πŸ” 293    πŸ’¬ 20    πŸ“Œ 42

@frederiksbro.bsky.social and I attempt to simplify the process, by highlighting the many similarities between various strategies and advocating for the combination of multiple ones. Have a look at the SI too, for a comprehensive overview of all strategies with representative examples!

04.02.2025 10:09 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

@lucalaraia is following 20 prominent accounts