Kedrov Lab @ HHU's Avatar

Kedrov Lab @ HHU

@kedrov-lab.bsky.social

"Synthetic Membrane Systems" group Biochemistry, University of Dรผsseldorf Membrane proteins, Good spirit and some Anarchy

292 Followers  |  221 Following  |  86 Posts  |  Joined: 26.12.2024  |  2.0635

Latest posts by kedrov-lab.bsky.social on Bluesky

Congrats, Micha & Co.! Best wishes for many successful developments! ๐Ÿ”ฌ

08.10.2025 14:51 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Junior Group Leader - Phage Biology & Biotechnology As a leading research institution for microbial biotechnology the Institute of Bio- and Geosciences - Biotechnology (IBG-1, https://www.fz-juelich.de/de/ibg/ibg-1 ) at the Forschungszentrum Jรผlich foc...

Please RT:
We have an opening for a junior group leader position in โ€žPhage Biology & Biotechnologyโ€œ.
www.fz-juelich.de/de/karriere/...

Interested candidates are encouraged to contact me via email for further details.

@spp2330.bsky.social; @mibinet.bsky.social

08.10.2025 06:50 โ€” ๐Ÿ‘ 25    ๐Ÿ” 44    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 1
Post image

SAVE THE DATE!

The 2026 UK CellularMicrobiologyNetwork meeting will be held 22nd - 23rd of June at @wwiem-qub.bsky.social in Belfast.

Researchers from the UK and beyond are invited to share exciting work on the mechanisms of host-pathogen interactions.

Follow us to stay tuned! www.ukcellmicro.org

06.10.2025 10:11 โ€” ๐Ÿ‘ 5    ๐Ÿ” 5    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 1
Preview
Structure of a distinct ฮฒ-barrel assembly machinery complex in the Bacteroidota - Nature Microbiology Structural and functional characterization of the ฮฒ-barrel assembly machinery complex in Bacteroidota reveals a distinct, seven-component complex with a large extracellular domain that may enable ฮฒ-barrelโ€“surface lipoprotein complex assembly.

Our paper on the Bacteroidota BAM complex is out in @natmicrobiol.nature.com! With @madejmar.bsky.social

We found that BAM in Bacteroides and Porphyromonas gingivalis has a distinct architecture from BAM in Proteobacteria.

doi.org/10.1038/s415...

02.10.2025 06:20 โ€” ๐Ÿ‘ 50    ๐Ÿ” 21    ๐Ÿ’ฌ 4    ๐Ÿ“Œ 2

๐ŸงตHow does a pathogen know it has entered its host?

New preprint!๐ŸŽ‰Itโ€™s a pleasure to share my first first-author preprint from my PhD journey!
We uncover a novel co-evolved peptideโ€“GPCR system in the fungus Ustilago maydis that senses host entry and triggers infection (doi.org/10.1101/2025...)
(1/5)

30.09.2025 07:24 โ€” ๐Ÿ‘ 18    ๐Ÿ” 8    ๐Ÿ’ฌ 2    ๐Ÿ“Œ 1
Post image

Congrats to Volker Haucke, Director at the Leibniz-FMP on being awarded the Ernst Schering Prize 2025 for his pioneering work on the function of signaling lipids that control how cells respond to hormones, nutrients and messengers.

23.09.2025 07:59 โ€” ๐Ÿ‘ 16    ๐Ÿ” 4    ๐Ÿ’ฌ 3    ๐Ÿ“Œ 3
Post image

Assistant/Associate Professor in Structural Biology, Biophysics or Biological Imaging

www.biozentrum.unibas.ch/open-positio...

#biozentrum #University #Basel #Professor #Structural #Biology #Biophysics #Biological #Imaging

29.09.2025 14:58 โ€” ๐Ÿ‘ 48    ๐Ÿ” 53    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 5
Preview
DFG muss Kรผrzungen vornehmen Inflation und steigende Kosten zwingen die Deutsche Forschungsgemeinschaft zum Sparen. Die Mittelaufwรผchse kompensierten die Preissteigerungen nicht.

Kรผrzungen. Kรผrzungen everywhere.

www.forschung-und-lehre.de/forschung/df...

26.09.2025 07:06 โ€” ๐Ÿ‘ 2    ๐Ÿ” 2    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Post image Post image Post image Post image

Our call for PhD students within our International Max Planck Research School for Cell, Developmental and Systems Biology is open! Apply until October 28th. We are looking forward hearing from you! imprs.mpi-cbg.de

25.09.2025 13:35 โ€” ๐Ÿ‘ 10    ๐Ÿ” 8    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 3

Really sad development, to my view...

21.09.2025 14:00 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Preview
Structure and substrate recognition by the Twin-arginine translocation (Tat) pathway core complex The twin-arginine translocation (Tat) system is a mechanistically unique protein transport pathway moving folded proteins across membranes (1-4). It is found in all domains of life and is essential fo...

Hah, one more story on Tat machinery detected! โค๏ธโ€๐Ÿ”ฅ Congratulations to the authors, teams of @smlea.bsky.social @pstansfeld.bsky.social and Ben Berks!
www.biorxiv.org/content/10.1...

21.09.2025 06:49 โ€” ๐Ÿ‘ 14    ๐Ÿ” 2    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Post image

Seems to be a hot topic - apparently, 2nd time Ig-Noble prize ๐Ÿ†!!

19.09.2025 16:31 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Very nice!!! ๐Ÿ‘ Congrats to all the teams involved - and Khaled for bringing the efforts together!

19.09.2025 14:54 โ€” ๐Ÿ‘ 2    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Preview
Library-free data-independent acquisition mass spectrometry enables comprehensive coverage of the cyanobacterial proteome Single-pot solid phase-enhanced sample preparation (SP3) and trifluoroacetic acid workflows open the door to high-throughput quantitative proteomics in cya

Very proud to share the latest development on our (w/ @synbiojazz.bsky.social) mission to bring fast and accessible methods to cyanobacterial proteomics.

Major highlight: 85% Synechococcus proteome coverage in a single shotgun experiment.

Out now in Plant Physiology!

doi.org/10.1093/plph...

19.09.2025 08:20 โ€” ๐Ÿ‘ 5    ๐Ÿ” 2    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 1

Congratulations!!! Totally thrilled to read! ๐Ÿคฉ

18.09.2025 18:21 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Incredible and LOUD!!! ๐ŸŒŸ๐Ÿค“๐Ÿ‘‡

18.09.2025 18:10 โ€” ๐Ÿ‘ 5    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
https://www.biorxiv.org/content/10.1101/2025.09.16.676506v1

How the twin-arginine translocase (Tat) system manages to transport folded proteins across membranes without any leaks? To answer this fundamental question we solved the first structure of TatB3C3 complex with bound cargo. Please check out new preprint!
t.co/962Kj9pt6F

18.09.2025 17:35 โ€” ๐Ÿ‘ 55    ๐Ÿ” 18    ๐Ÿ’ฌ 2    ๐Ÿ“Œ 1

Molecular structure of the ESCRT III-based archaeal CdvAB cell division machinery www.biorxiv.org/content/10.1101/2025.09.15.676241v1 #cryoEM

16.09.2025 07:11 โ€” ๐Ÿ‘ 13    ๐Ÿ” 6    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Happy to share that our story on the bacterial archaellum was published today in @natmicrobiol.nature.com
www.nature.com/articles/s41...

Congrats to the authors: @sshamphavi.bsky.social @loumollat.bsky.social @mariejoest.bsky.social Najwa Taib and @sgribaldo.bsky.social

17.09.2025 17:41 โ€” ๐Ÿ‘ 119    ๐Ÿ” 58    ๐Ÿ’ฌ 7    ๐Ÿ“Œ 8

And a Big Applause to the Organizers! ๐Ÿ‘๐Ÿป

17.09.2025 15:50 โ€” ๐Ÿ‘ 3    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

4 days left to apply for this #PhD position on #nanopore trapping at @unibas.ch in Switzerland๐Ÿ‡จ๐Ÿ‡ญ:

16.09.2025 12:21 โ€” ๐Ÿ‘ 5    ๐Ÿ” 2    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
Post image

Happy to share the molecular mechanism of activation of kainate-subtype ionotropic glutamate receptor GluK2 in complex with auxiliary subunits Neto2. In both closed/apo and open states, ligand-binding domain (LBD) layer has 2-fold rotational symmetry!
www.nature.com/articles/s41...

11.09.2025 13:17 โ€” ๐Ÿ‘ 20    ๐Ÿ” 4    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Congratulations to Kai Simons, one of our founding directors, for receiving the Cothenius-Medal of the German National Academy of Sciences Leopoldina @leopoldina.org for his insights into the function of cell membranes. ๐ŸŽ‰ www.mpi-cbg.de/news-outreac...

05.09.2025 12:08 โ€” ๐Ÿ‘ 36    ๐Ÿ” 10    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Post image

Bacterial cell widening alters periplasmic size and activates envelope stress responses
Kerwyn Huang, @typaslab.bsky.social et al find that E. coli outer-membrane protein RcsF senses reduced periplasm thickness due to increased cell width, & activates Rcs signaling
www.embopress.org/doi/full/10....

04.09.2025 09:39 โ€” ๐Ÿ‘ 31    ๐Ÿ” 14    ๐Ÿ’ฌ 2    ๐Ÿ“Œ 0
Post image

Gegen den russlรคndischen Imperialismus - gegen das russlรคndische Mรถrderregime: Dรผsseldorf, 6. September 2025

01.09.2025 08:50 โ€” ๐Ÿ‘ 271    ๐Ÿ” 74    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
Hรถrsaalfoto mit dem Logo von Tรผren auf mit der Maus 2025

Hรถrsaalfoto mit dem Logo von Tรผren auf mit der Maus 2025

๐Ÿญ 3. Oktober: Tรผren auf mit der Maus
Am 03.10.2025 findet wieder der Mausรถffnertag statt! Daran teil nimmt auch die HHU: Um 11:00 Uhr kรถnnen bis zu 150 Teilnehmende eine Experimentalvorlesung zum Thema "Seltene Erden" besuchen. 1/2
@daumannl.bsky.social

01.09.2025 13:32 โ€” ๐Ÿ‘ 15    ๐Ÿ” 3    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 1
Preview
Fat microscopy: Imaging lipids in cells Dresden research team develops novel imaging approach to visualize individual lipids in cells and uncovers the main transport mechanism for lipids within the cell.

Research team @nadlerlab.bsky.social, A. Honigmann @biotec-tud.bsky.social, B.Drobot @hzdr.bsky.social, M. Hof @heyrovskeho-ustav.bsky.social develops approach to visualize lipids in cells & uncovers the main transport mechanism for lipids within the cell. @nature.com www.mpi-cbg.de/news-outreac...

29.08.2025 08:24 โ€” ๐Ÿ‘ 58    ๐Ÿ” 20    ๐Ÿ’ฌ 2    ๐Ÿ“Œ 2
Preview
DeFrND: detergent-free reconstitution into native nanodiscs with designer membrane scaffold peptides - Nature Communications To bypass the limitations of detergents, Ren et al. developed peptide scaffolds that extract membrane proteins directly into lipid nanodiscs, preserving the native environment for structural and funct...

Interesting read, with so many bright names in the co-author list!โค๏ธโ€๐Ÿ”ฅ And once again, the Transparent Peer Review file is worthy reading too... โš”๏ธ
www.nature.com/articles/s41...

27.08.2025 20:16 โ€” ๐Ÿ‘ 10    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

DeFrND: detergent-free reconstitution into native nanodiscs with designer membrane scaffold peptides pubmed.ncbi.nlm.nih.gov/40858559/ #cryoEM

27.08.2025 15:32 โ€” ๐Ÿ‘ 10    ๐Ÿ” 4    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

@kedrov-lab is following 20 prominent accounts