Michael Hothorn

Metabolism, Perception, and Functions of Inositol (Pyro)Phosphates in Plants Inositol phosphates and pyrophosphates are small, water-soluble molecules involved in a range of physiological processes across eukaryotic organisms, including plants. Over the past two decades, signi...

doi.org/10.1146/annu...

Very nice & complete review on inositol pyrophosphate metabolism and signaling in plants by Ricardo Giehl @leibnizipk.bsky.social and @gabrielschaaf.bsky.social @unibonn.bsky.social . Also includes an impressive to-do-list...

Really excited to join IMB for this new scientific endeavour!

Assistant Professor (Tenure Track) of Sustainable Plant Nutrition The Department of Environmental Systems Science (www.usys.ethz.ch) at ETH Zurich invites applications for the above-mentioned position.

Job opportunity: Join ETH Zurich as a Tenure Track Assistant Professor in Sustainable Plant Nutrition.
Application deadline: 28th February 2026.
Explore more details at the link. #PlantSciJobs

ethz.ch/en/the-eth-z...

New preprint out! Zhoubo Hu et al "A redox-regulated RCC1-like protein controls catalase activity in Arabidopsis". We identify CAIR1, a UVR8-interacting protein, as a redox-responsive regulator of catalase localization and activity, maintaining cellular ROS balance. 🌱
www.biorxiv.org/content/10.6...

❗📢 The SNSF is adjusting its project funding as of 1 April 2026. Our goal is to stabilise success rates at a level that ensures funding for research of the highest quality. This is how we guarantee a fair chance for all researchers.

➡️ sohub.io/5x59

Please share!
My group at @zmbp-tuebingen.bsky.social is offering a post-doctoral position (4 years). We look for a structural biologist with experience in Cryo-EM/Cryo-ET to investigate the mechanisms of host invasion by pathogenic fungi. Deadline February 28th!
uni-tuebingen.de/universitaet...

Multiple protein structure alignment at scale with FoldMason Protein structure is conserved beyond sequence, making multiple structural alignment (MSTA) essential for analyzing distantly related proteins. Computational prediction methods have vastly extended ou...

FoldMason is out now in @science.org. It generates accurate multiple structure alignments for thousands of protein structures in seconds. Great work by Cameron L. M. Gilchrist and @milot.bsky.social.
📄 www.science.org/doi/10.1126/...
🌐 search.foldseek.com/foldmason
💾 github.com/steineggerla...

Ministerin Holzleitner prescht mit Drei-Milliarden-Budget für Grundlagenforschung vor 375 Millionen Euro mehr für drei Jahre für die Grundlagenforschung, FTI-Pakt bleibt aber weiterhin in Schwebe – Kürzungen bei angewandter Forschung werden befürchtet

Forschungsförderung ist ein wichtiger Teil unserer Zukunftsvorsorge.

Österreich investiert in den nächsten 3 Jahren 3 Mrd € in die Grundlagenforschung. Ein reales Wachstum - selbst angesichts der hohen Inflation der letzten Jahre 👏

www.derstandard.at/story/300000...

@sbfi.admin.ch @snsf.ch 🧪

Full Professor and Chair Laboratory of Biophysics We are looking for a Full Professor in the Biophysics chair group, part of Wageningen University & Research (WUR)

www.wur.nl/en/vacancy/f...

Become our new colleague (and next door neighbor) and lead a chair/group/department of Biophysics at Wageningen University. Reach out to me for info and please spread!!!

I said serine, not Siri

Complexity at the ribosomal polypeptide tunnel exit. The major N-terminal acetyltransferase NatA may form different complexes on the ribosome to facilitate protein maturation. By Marius Klein & Klemens Wild in Irmgard Sinning's lab BZH & Nina McTiernan in my lab. www.nature.com/articles/s41...

PhD opportunity in the newly minted RO2T Respiration Group! Please share!
Interested in root biology, oxygen dynamics, imaging & modelling? We’re recruiting a PhD student at the University of Nottingham.
Deadline 15th February.
jobs.nottingham.ac.uk/Vacancy.aspx...
#plantscijobs #plantscience

New Brief Communication: "A CRISPR-based sequence proximity binding protein labelling system for scanning upstream regulatory proteins" rdcu.be/eZLUP

CRISPR-based proximity labelling system to profile DNA-binding proteins such as PIF4 transcription factor .

ONE WEEK LEFT TO APPLY: We’re hiring 4 roles at UWA's Plant Synbio Innovation Centre: Facility Manager + 3 Postdocs (single-cell genomics/screening; molecular tools; construct prototyping) bit.ly/4qfoftG bit.ly/3MFgD59 bit.ly/4pFT6jf bit.ly/48VkgLw

Apply by Tuesday 27 Jan 2026 (11:55pm AWST)

A Marchantia gemmaling producing ectopic vegetative propagules

Happy to share the pre-print on GEMMIFER, a novel ERF required for the initiation of gemma in Marchantia. One of the coolest phenotypes that I have ever seen. Congratulations to Yuki and Go, who led this research. #PlantScience @biorxiv-plants.bsky.social www.biorxiv.org/content/10.6...

Investir dans la recherche scientifique est dans l’intérêt de notre pays - Le Temps OPINION. Le parlement se penche sur une potentielle baisse d’au moins 10% du budget du Fonds national suisse dès 2027. Si ce projet passe la rampe, la Suisse fragilisera sa capacité d’innovation, sa c...

Excellente tribune de @torstenschwede.bsky.social à propos de l'importance de soutenir le @snf-fns.ch
www.letemps.ch/opinions/inv... www.letemps.ch/opinions/inv...

Photo of the interior of award-winning Sainsbury Laboratory Cambridge University building. Glass walls look into the research labs and naturally lit staircase and walkway with study boxes looking into the Botanic Garden

Launch your own independent research group!

2x David Sainsbury Career Development Fellowships at @slcuplants.bsky.social

📆 Apply by 30 Jan 2026

More info:
👉 www.slcu.cam.ac.uk/careers/grou...
Job details:
👉 www.cam.ac.uk/jobs/david-s...

Please share this post #PlantSciJobs #PlantSciJob

Künstliche Intelligenz in der Begutachtung

DFG erlaubt Einsatz von KI in der Begutachtung.

Wenn wir jetzt noch die AI dazu kriegen, die komplette Forschung zu machen, haben wir den Menschen komplett von der Last des Forschungsprozzeses befreit und er kann sich komplett auf wichtige Dinge wie Reisekostenerstattungsanträge konzentrieren.

Next-generation genome editing: no transgene, no tissue culture New approaches to engineering plant genomes have the potential to improve agriculture. However, transgenes insertion and tissue culture have become bottlenecks to genome-editing technology becoming wi...

Going back full circle, with particle bombardment

www.cell.com/trends/plant...

@fxrico.bsky.social deleted the single BSU1 gene in Marchantia, resulting in a mass of undifferentiated cells & strong patterning defects. Cell cycle markers are highly active in the thallus. Our data point to a function for Kelch phosphatases in the cell cycle not in BR signaling (6/6).

In Andrea’s structure the C-terminal tail of BSU1 is phosphorylated and bound to the active site. Andrea and Pierre showed that this phosphorylation is caused by the CDK1-cyclin-CKS1 complex, very similar to PP1, where no structure is available. The phosphorylation inhibits BSU1 activity (5/6).

Oded and Felix Rico generated CRISPR/Cas9 knock-out mutants of all Kelch phosphatases in Arabidopsis. These mutants have a fertility defect, suggesting a function in embryo development, many more stomata than wild type, but wild type-like BR responses. (4/6)

BSU1 was originally identified in an activation tagging screen in the weak BR receptor mutant bri1-5. Oded Pri-Tal found, to our surprise, that also phosphatase-dead versions of the enzyme can rescue the bri1-5 mutant. A mutant in the RVxF substrate binding groove does not rescue. (3/6)

A crystal structure from Andrea Moretti of the Kelch phosphatase BSU1 reveals that it looks virtually identical to PP1, a Ser/Thr phosphatase involved in cell cycle regulation. Consistently, Pierre Raia could show that BSU1 is an efficient Ser/Thr, not a tyrosine phosphatase in vitro. (2/6)

Plant Kelch phosphatases are Ser/Thr phosphatases involved in cell cycle regulation Brassinosteroids (BRs) are plant steroid hormones sensed at the cell surface by the membrane receptor kinase BRI1. Activation of BRI1 leads to the dephosphorylation of BZR1/BES1 transcription factors ...

Our new year starts of course with new preprint on brassinosteroid signaling tinyurl.com/nhzcfkxd. We re-analyzed the function of Kelch phosphatases, which were previously characterized as protein tyrosine phosphatases that dephosphorylate the critical pTyr200 in the GSK3 kinase BIN2. (1/6)

Assistant Professor (Tenure Track) of Sustainable Plant Nutrition

A great tenure track position (Assistant Professor) of Sustainable Plant Nutrition @ethz.ch @usyseth.bsky.social @johansix.bsky.social ! Deadline to apply: 28/02/2026.

ethz.ch/en/the-eth-z...

A 1.25 A!!! cryo EM structure of rubisco.

Project funding restrictions envisaged The SNSF is responding to increased demand from researchers in order to ensure evaluation quality and stabilise success rates.

The SNSF is considering restrictions for its Project funding. Goal: to ensure the quality of evaluation & stable success rates despite an increasing number of applications and limited funding. The final decision will be made in January 2026.

👉 buff.ly/iGOCf7R

#research #science

Mainz carnival - Wikipedia

Have a great start in Mainz Laura! I really hope you like en.wikipedia.org/wiki/Mainz_c...