Silvia Ramundo

The ClaRa retreat V1 was a blast!

The Clausen + Ramundo folks teamed up for two days of science, cooking, and good chaos — plus some skiing ⛷️

Then came the pipetting showdown… and the whale trophy swam home with us 🐋🏆!

Will the @clausenlab.bsky.social win it back next year? Probably 😅 …

Please share!
My group at @zmbp-tuebingen.bsky.social is offering a post-doctoral position (4 years). We look for a structural biologist with experience in Cryo-EM/Cryo-ET to investigate the mechanisms of host invasion by pathogenic fungi. Deadline February 28th!
uni-tuebingen.de/universitaet...

Four representative slices of cryo-tomograms showing annotated organelles.

New on the CryoET Data Portal: ~27,000 tomograms of affinity-captured lysosomes from HEK293T cells across 4 physiological states. Includes raw data, AreTomo3 reconstructions & Membrain-Seg annotations. Openly available for reuse!

cryoetdataportal.czscience.com/depositions/...

ADAM-tRNA-seq: an optimized approach for demultiplexing and enhanced hierarchal mapping in direct tRNA sequencing Abstract. Transfer RNAs (tRNAs) play an essential role in protein synthesis and cellular homeostasis, and their dysregulation is associated with various hu

Interested in direct tRNA-seq by Nanopore? We developed a new RNA-based barcoding aproach for seq parallelization; it is also cost-saving. Scripts available on github. #tRNA #Nanopore

track.smtpsendmail.com/9032119/c?p=...

Having fun with the microscope lately. Here’s one of my favourite artsy and slightly psychedelic shots of #Marchantia chloroplasts and a fluorescent membrane reporter. (z-stack maximum projection)

Can't wait for this meeting!

Here we go again! Join us in Vienna, May 21–22, for two days of plant science—talks, discussions, and celebration of what makes plants both beautiful and essential 💚Full program + registration here: www.oeaw.ac.at/gmi/news-eve...
Come be part of it — each of you counts!

Mendel Early Career Symposium 2026 Register below for the 2026 Mendel Early Career Symposium21-22 May 2026 at the Campus-Vienna-Biocenter, AUSTRIA   Please select the events you would like to attend and add them to the cart in order ...

Interested in giving a talk? Submit your abstract by 13 March to be considered.

More Information about the event and registration here: events.vbc.ac.at/gmi_events/m...

#Mendel_ECR_26 #WhereKnowledgeGrows

In addition to keynote lectures by @emmanuellebayer.bsky.social and @nkwhiteman.bsky.social, the symposium features a How-"Do-You-Do-It?" workshop on ChimeraX and Alphafold. A networking dinner at the Vienna Rathauskeller will follow, kindly supported by the City of Vienna.

Registration is now open! The 4th edition of the Mendel Early Career Symposium will take place on 21-22 May at the GMI, part of the @viennabiocenter.bsky.social. This two-day event brings together researchers across career stages to discuss the latest research in all areas of plant science.

Using micropatterning & thousands of hours on the microscope
@manuelthery.bsky.social and the #CytoMorphoLab reimagined the Musée D’Orsay. Accompanied by an orchestra and poet, their images transported us into the cellular universe. I remembered why I am a cell biologist. All of this is in us. Wow!

“What excites me is not what we’ve already done, but what we still don’t know how to do.”

Nobel laureate David Baker in his lab at the Institute for Protein Design, surrounded by the everyday tools of discovery. This is what the frontier looks like up close.

Seattle (2026) @nationalacademies.org

Construction of complex and diverse DNA sequences using DNA three-way junctions - Nature Sidewinder enables high-fidelity DNA assembly by separating the information that guides assembly from the final assembled sequence.

Nature research paper: Construction of complex and diverse DNA sequences using DNA three-way junctions

go.nature.com/4qu2ExZ

Psilocybin treatment extends cellular lifespan and improves survival of aged mice - npj Aging npj Aging - Psilocybin treatment extends cellular lifespan and improves survival of aged mice

Amsterdam for the weekend... Lifespan extension included! J U S T
K I D D I N G 😉 www.nature.com/articles/s41...

Prepare to be jelly @atinygreencell.bsky.social : this little pearl is way less complicated and more efficient than what you’re dealing with… 🙃

If you're doing innovative research about #microbiota and received an MD &/or PhD in last 10 yrs don’t forget to apply for the NOSTER & @science.org Microbiome Prize! Grand Prize: $25K & your essay published in Science Magazine
Deadline: Feb 14th
Enter: buff.ly/5GKZgUN

What?!? & Why? @science.org
I know the price is very reasonable… but let’s put it this way: how would you feel if scientists put a very reasonable price for any manuscript they review for you? Let’s talk about this.

Lhcf2 in the peripheral antenna is essential for non-photochemical quenching and Lhcx1 accumulation in the diatom Chaetoceros gracilis www.biorxiv.org/content/10.6...

A fantastic opportunity to work in Geneva if you are in the field of origins of life!

Loved seeing this paper: it shows how our favorite chloroplast protease (Clp) supports C4 plants as they protect themselves from excess light while building specialized chloroplasts—tying protein quality control to crop resilience! 💚

YouTube video by Piece of Magic Entertainment OCEAN with David Attenborough | 'Bottom Trawling' Official Clip

www.youtube.com/watch?v=eLxm...

I'm recruiting 1-2 grad students through the AITHYRA-CeMM PhD program! Applications are due January 30th. This is a fully-funded PhD program, combining AI and biology to advance biological discovery. Please forward to anyone who may be interested! You can apply here: apply.cemm.at

So: if you have worked on #Vaults (even briefly) and have experiments/approaches that did not work, please share here—what did you try, and what failed? 3/3

Many of us would love to pin down their function, and honestly, the first step might be to collect all the negative results from everyone who has tried to crack this problem. 2/3

Last Friday over dinner, we talked with @svenklumpe.bsky.social and @jnoms.bsky.social about this very creative paper—and quickly went off track. Why? Because, as Sven put it, Vaults ( #Vaults ) remain the “siren 🧜‍♀️ of cell biology 🔬” intriguing and attractive, but maddeningly hard to figure out. 1/3

portraittheater: Women in Science In recognition of the International Day of Women and Girls in Science, we are organizing a special event on ISTA campus.The program will feature a performance of “Curie_Meitner_Lamarr_...

Kudos to ISTA (@istaresearch.bsky.social) for organizing the screening of this documentary on Lise Meitner, Marie Curie, and Hedy Lamarr on February 10! I am looking forward to it 💚 www.ista.ac.at/en/news-even...

My son is Pure Energy (If there were a son-to-mom energy transfer option, I would sign up immediately—even a tiny 10% top-up would be a game-changer!)

Artificial intelligence tools expand scientists’ impact but contract science’s focus - Nature Artificial intelligence boosts individual scientists’ output, citations and career progression, but collectively narrows research diversity and reduces collaboration, concentrating work in data-rich a...

One of my concerns with AI-assisted research in biology is that we're already looking only in the lamplight and AI incentivizes us to narrow the beam. Seems like it's happening...
www.nature.com/articles/s41...

Mitochondrial ligase MAPL drives pyroptotic cell death Nature Structural & Molecular Biology, Published online: 15 January 2026; doi:10.1038/s41594-025-01735-xMitochondrial ligase MAPL drives pyroptotic cell death

New online: Mitochondrial ligase MAPL drives pyroptotic cell death