Eleonora Pali

Attenuation of social preference and alteration of cortical neurons following adolescent cerebellar nuclei perturbation - Molecular Psychiatry Molecular Psychiatry - Attenuation of social preference and alteration of cortical neurons following adolescent cerebellar nuclei perturbation

Our manuscript showing cerebellar nuclei impacts on distal cortical activity, structure, and social behavior is now out! 🧪🔬

www.nature.com/articles/s41...

15.12.2025 18:00 — 👍 11    🔁 2    💬 1    📌 0

One of the most beautiful things in the world❤️ #patchclamp #EIRatio

17.10.2025 17:14 — 👍 32    🔁 5    💬 2    📌 1

Portail Emploi CNRS - Offre d'emploi - Postdoctoral researcher in human neurobiology (M/F)

🧠 Opportunity for a post-doctoral position on human neurobiology, funded by the @erc.europa.eu!
🧫You want to use human pluripotent stem cell based models to understand the evolution of human cerebellar neurons and disorders, this position is for you!
🔗Apply here: emploi.cnrs.fr/Offres/CDD/U...

30.07.2025 08:26 — 👍 20    🔁 23    💬 1    📌 2

Had such wonderful days in Oslo for #FRM2025. It was a well-organized and truly inspiring conference! Thanks to everyone who stopped by my poster on the role of #cerebellar Purkinje cells in a mouse model of #autism, I really appreciated all your comments and feedback!

21.06.2025 16:12 — 👍 1    🔁 0    💬 0    📌 0

Synaptic Plasticity: A new mode of action for unconventional NMDA receptors Presynaptic NMDA receptors can shape timing-dependent long-term depression in a way that departs from their classic postsynaptic role.

A very nice Insight article in eLife by Ikuko Smith on our forthcoming eLife paper on non-ionotropic presynaptic NMDA receptor signalling in spike-timing-dependent long-term depression. elifesciences.org/articles/107...

24.05.2025 19:10 — 👍 7    🔁 1    💬 0    📌 0

Benchmarking cerebellar organoids to model autism spectrum disorder and human brain evolution While cortical organoids have been used to model different facets of neurodevelopmental conditions and human brain evolution, cerebellar organoids have not yet featured so prominently in the same cont...

New preprint alert 📣
#Cerebellum, organoid, autism & brain evolution 🧪 🧫🧠🧬
Collaboration with G. Testa; fruit of years of work by smart students, led by postdoc Davide Aprile. Organoids to understand better the developmental basis of autism (focus: CHD8) & sapiens brain evolution (focus: CADPS2) 🧵

16.05.2025 11:08 — 👍 59    🔁 26    💬 5    📌 2

Coincidence detection between apical and basal dendrites drives STDP in cerebellar Golgi cells - Communications Biology Cerebellar mf-GoC synapses show anti-symmetric STDP, driven by action potential timing, NMDA receptor activation, and Ca²⁺ dynamics, with inhibitory input capable of reversing the plasticity rules.

Cerebellar mf-GoC synapses show anti-symmetric STDP, driven by action potential timing, NMDA receptor activation, and Ca²⁺ dynamics, with inhibitory input capable of reversing the plasticity rules. @elepali.bsky.social
www.nature.com/articles/s42...

15.05.2025 18:23 — 👍 2    🔁 1    💬 0    📌 0

Coincidence detection between apical and basal dendrites drives STDP in cerebellar Golgi cells Communications Biology - Cerebellar mf-GoC synapses show anti-symmetric STDP, driven by action potential timing, NMDA receptor activation, and Ca²⁺ dynamics, with inhibitory input...

Excited to share my PhD work on spike-timing dependent plasticity in cerebellar Golgi cells, just published with @springernature.com in @commsbio.nature.com.
Read here: rdcu.be/elN6L

13.05.2025 08:40 — 👍 9    🔁 2    💬 0    📌 0

Made a starter pack for researchers who are actively working on or have an interest in the cerebellum.

DM me to be added or reply to this thread!

🧠🤏🏻

go.bsky.app/7X4ekSH

#neuroscience #neuroskyence #cerebellum #neuroimaging #dbs #fmri

25.11.2024 21:06 — 👍 46    🔁 12    💬 27    📌 1

🙋🏻‍♀️ could I be added, please?

05.12.2024 21:50 — 👍 1    🔁 0    💬 1    📌 0

A black and white offering for the post-Thanksgiving #FluorescenceFriday.
Cerebellum, because one never forgets one's first love 🤍🖤🐭
#neuroskyence #microscopy

29.11.2024 14:11 — 👍 53    🔁 7    💬 1    📌 0

Could not believe such thing did not exist. Let me know if you want to be added (/removed)

go.bsky.app/RuCRCgX

16.11.2024 14:16 — 👍 48    🔁 14    💬 48    📌 1

🙋🏻‍♀️

19.11.2024 11:54 — 👍 1    🔁 0    💬 1    📌 0

A low-cost perfusion heating system for slice electrophysiology - Scientific Reports Scientific Reports - A low-cost perfusion heating system for slice electrophysiology

Are you building a patch-clamp setup, and would like a cheap heating system? Have you ever wondered how temperature changes the membrane properties of MSNs? Then you might like our latest paper, out now!

www.nature.com/articles/s41...

18.11.2024 19:03 — 👍 74    🔁 28    💬 13    📌 2