Frederik Post

My first PhD paper on the spatial characterization of colon organoids is finally out!
Thanks to @hausmannannika.bsky.social for spearheading this collaboration with me. Read more about the study in the post by @mannlab.bsky.social.

Very happy to share that part of my postdoc work @ucph.bsky.social @kimbakjensen.bsky.social lab is out now in @cp-cellsystems.bsky.social!

In close collaboration with @freddyomics.bsky.social @mannlab.bsky.social we show that orthotopically transplanted organoids recapitulate in vivo phenotypes 👇🏼

Deep Visual Proteomics maps proteotoxicity in a genetic liver disease - Nature High-resolution spatial proteomics were used to map molecular events during hepatocyte stress in pseudotime across all fibrosis stages, recapitulating known disease progression markers and revealing e...

Our paper is out in Nature today! We use Deep Visual Proteomics (DVP) to dissect α1-antitrypsin deficiency (AATD) in human liver at single-cell resolution.
Let us take a tour through proteotoxic stress in intact human tissue — one hepatocyte at a time.
www.nature.com/articles/s41...

Plasma proteome variation and its genetic determinants in children and adolescents - Nature Genetics This mass spectrometry-based proteomic study profiles the plasma proteome in 2,147 children and adolescents and reveals its association with age, sex, puberty, body mass index and genetics.

Out today in Nature Genetics: Using MS-based proteomics, we mapped 1,200+ plasma proteins in 2,100+ children, showing how genetics & development shape blood protein levels during childhood.
nature.com/articles/s41588-025-02089-2
#PediatricProteomics #pQTL
First author @liliniu.bsky.social explains ⬇️