David Berron

‼️NEW PREPRINT‼️

What if you could take a normal 3T T1w MRI and make it look like it was acquired from a 7T scanner?

That's exactly what we do using AI in our new preprint!

Link: arxiv.org/abs/2507.13782

#neuroskyence #neurosky #compneuro #AI #datascience #neurology #mrisky #neuroimaging

Save the date: #SAA2026 will take place on 3-5 August 226 in Vienna 🇦🇹. We will be hosted by @lauramkoenig.bsky.social @alearuf.bsky.social @univie.ac.at

A scoping review of remote and unsupervised digital cognitive assessments in preclinical Alzheimer’s disease - npj Digital Medicine npj Digital Medicine - A scoping review of remote and unsupervised digital cognitive assessments in preclinical Alzheimer’s disease

Paper alert! @davidberron.bsky.social and team tackled: What are the recent advances in remote and unsupervised digital cognitive assessment of preclinical AD?
The review covers 28 studies and 23 tools, offering a clear overview of recent advances and challenges.

👉 www.nature.com/articles/s41...

There are days in life that shake you.

I’m shattered 💔 to share that I just found out that the US Government terminated my 2024 NIH Director’s Early Independence Award (~$2 million), threatening my long-promised assistant professor job at Columbia University
& academic career... 1/🧵

SharePic: Was die Wissenschaft jetzt braucht - 6 Punkte für die neue Bundesregierung

🚀 Forschungs- und Innovationswende in Deutschland: Es ist Zeit für große Schritte! 🏃

Die digitale Transformation wartet nicht auf uns. Die #Helmholtz-Gemeinschaft zeigt in 6 Punkten, worauf es in den Koalitionsverhandlungen jetzt ankommt, um Deutschland an die #Innovationsspitze zu bringen. 🧵
(1/6)

Demenzdiagnosen sind aufwendig und werden oft spät gestellt. @davidberron.bsky.social und Kollegen am @dzne.science in Magdeburg haben eine 📱-App mit Gedächtnistests entwickelt. Damit können schon früh Gedächtnisprobleme erkannt werden, die auf eine #Demenz hinweisen ➡️ tinyurl.com/4ynfazxm #dementia

Many thanks to my colleagues for providing access to all the apps and tools! @jhassenstab.bsky.social #ARC #KathrynPapp #BRANCH #SietskeSikkes #AlexandraKönig #ki:elements @merijnmestdagh.bsky.social #m-path @dzne.bsky.social

It was an intense two days at the seminar on #digital #approaches in #neuropsychology as part of the Psychology Master's program in Clinical Neuroscience.
The highlight was the hands-on experience with digital tools in different use cases, each highlighting a specific strength of digital approaches

Would love to be added, thanks!

I‘d love to be added - thanks!

A scoping review of remote and unsupervised digital cognitive assessments in preclinical Alzheimer's disease https://www.medrxiv.org/content/10.1101/2024.09.25.24314349v1 Subtle cognitive changes in preclinical Alzheimer's disease (AD) are difficult to detect using tradi

A scoping review of remote and unsupervised digital cognitive assessments in preclinical Alzheimer's disease https://www.medrxiv.org/content/10.1101/2024.09.25.24314349v1

Thanks! Would love to join as well!

OK folks, I've started an episodic memory starter pack. By no means a full list so reply below if you're an episodic memory nerd! go.bsky.app/2mtNK43

Many thanks to co-authors OskarHansson, Sebastian Palmqvist, Emrah Düzel, Shorena Janelidze, Pontus Tideman, Erik Stomrud, Emil Olsson and Felix Andersson and everyone involved in the Swedish BioFINDER studies @dzne.bsky.social

Can remote and unsupervised smartphone-based cognitive assessments detect cognitive impairment in AD and, in combination with novel blood biomarkers, predict future cognitive decline? We investigated this in the Swedish BioFINDER study - check out our new paper tinyurl.com/DigitalBioma...

Postdoctoral Researcher (f/m/x) 4064/2024/5

We have an open postdoc position in my group @ DZNE (@dzne.bsky.social) If you are passionate about neuroimaging, memory, digital cognitive markers and understanding cognitive impairment with its underlying brain dysfunction in early stages of AD, please apply here: www.tinyurl.com/CCNpostdoc

Honoured and grateful to have been awarded the BrightFocus
postdoctoral fellowship for research into the early stages of Alzheimer's disease. A huge thank you to my mentor @davidberron.bsky.social! So excited to work on this project in the years to come 🎉

The picture shows an illustration of different people. On top is the following quote from the DZNE Executive Board: "Ideas need diversity and solidarity".

Ideas need Diversity and Cooperation: That is why we take a clear stand against discrimination, racism and narrow-mindedness - and for an open, free society, for democracy and diversity.
Our full statement 👉 www.linkedin.com/feed/update/...

New paper day! "Multiband acquisition sequences for fMRI: Proceed with caution" apertureneuro.org/article/9129... VERY proud of this one as it's my first editorial piece. Big thanks to @layerfmri.bsky.social and @fmri-today.bsky.social for asking me to do it. #neuroskyence

Alright, I’m finally leaving Twitter so I’ll start using this app for real.
I hope it’ll be more similar to what I loved with the science Twitter I loved and learned so much from years ago.
But first, wishing everyone a good break!

Check out our new review on the amygdala in AD, led by the fantastic Kaitlin Stouffer! It was about time that this structure receives more attention in AD - we even argue for its involvement in an additional NFT progression pathway

tinyurl.com/amygdalaAD

Thread below👇🧵 (1/8)

Many thanks to this incredible team, with a special shout-out to my co-senior Laura Wisse as well as Menno Witter, @xenianeuro.bsky.social , Emrah Düzel, Maurits Johansson, Byron Creese and Michael Miller. This was a really fun project to work on! @dzne.bsky.social (8/8)

Finally, we discuss the functional roles of the amygdala highlighting the correspondence between NFT accumulation and symptomatic profiles in Alzheimer’s disease patients (7/8)

Using ultra-high field 7T MRI 🧲, we present evidence for a functional pathway in humans connecting the amygdala and other early NFT accumulation sites in the anterior hippocampus 🍤 (6/8)

That's where the amygdala comes into play. We argue that, given its high connectivity with the early hippocampal accumulation sites, the amygdala may be part of an additional pathway of NFT progression 🧐 (5/8)

However, this does not entirely track with the assumption that NFT progression follows connectivity pathways! The lateral entorhinal region has preferential connections rather with posterior than anterior hippocampus 👀 . Thus, anterior NFTs lack a plausible trajectory (4/8)

We propose that the amygdala plays a role in how NFT pathology progresses within the medial temporal lobe. Within the hippocampus, early NFTs are found in anterior and posterior regions, with a paucity of pathology in the middle. (3/8)

The amygdala has been shown to be affected by early NFT pathology in Alzheimer's already in the seminal work by Braak & Braak. After years of the hippocampus and entorhinal cortex stealing the show, recent advances in neuroimaging brought the amygdala back on stage 🪩 (2/8)

Check out our new review on the amygdala in AD, led by the fantastic Kaitlin Stouffer! It was about time that this structure receives more attention in AD - we even argue for its involvement in an additional NFT progression pathway

tinyurl.com/amygdalaAD

Thread below👇🧵 (1/8)

Save the date!! 🗓️

April 11-12, 2024 in Toronto 🍁 (prior to CNS)

The HSG will hold a training opportunity to learn the harmonized body protocol for hippocampal subfields! 🧠🍤

A preprint of the protocol and additional registration details are forthcoming.