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The Casual Hiker

@sfhiker.bsky.social

SF-based computational biologist, hiker, nerd. All things history/prehistory, science, tech, nature, and sustainability. Also SF and California politics.

103 Followers  |  143 Following  |  191 Posts  |  Joined: 18.07.2023  |  2.0449

Latest posts by sfhiker.bsky.social on Bluesky

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A river otter chomping on a fish at Phoenix Lake today.

13.10.2025 03:30 β€” πŸ‘ 13    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0

Today my @nytimes.com colleagues and I are launching a new series called Lost Science. We interview US scientists who can no longer discover something new about our world, thanks to this yearβ€˜s cuts. Here is my first interview with a scientist who studied bees and fires. Gift link: nyti.ms/3IWXbiE

08.10.2025 23:29 β€” πŸ‘ 4740    πŸ” 1838    πŸ’¬ 142    πŸ“Œ 83

Almost petted it. :)

14.09.2025 07:13 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Juvenile bobcat encounter on Tennessee Valley Trail.

14.09.2025 04:23 β€” πŸ‘ 6    πŸ” 0    πŸ’¬ 2    πŸ“Œ 0
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Tech Billboards Are All Over San Francisco. Can You Decode Them?

www.nytimes.com/2025/08/04/b...

05.08.2025 04:27 β€” πŸ‘ 4    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0

In Turkey, when authoritarianism took hold, satire was one of the first casualties. Political comedy shows disappearedβ€”now, airing one could land you in jail.

Dictatorships always follow the same playbook.

18.07.2025 15:39 β€” πŸ‘ 12    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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4.6 Billion Years On, the Sun Is Having a Moment In the past two years, without much notice, solar power has begun to truly transform the world’s energy system.

Renewable energy is humming along despite the setbacks: β€œβ€¦people are now putting up a gigawatt’s worth of solar panels, the rough equivalent of the power generated by one coal-fired plant, every fifteen hours.” www.newyorker.com/news/annals-...

10.07.2025 03:16 β€” πŸ‘ 7    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0
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πŸ”¬API-first feature extraction for image-based profiling workflows

If you need to obtain interpretable features from your segmented microscopy images, but want to do it in a fully automated way, we know the struggle.

1/6

08.07.2025 19:22 β€” πŸ‘ 46    πŸ” 20    πŸ’¬ 1    πŸ“Œ 0

For many years while I was running a scientific skepticism site/podcast I repeated the mantra "vaccines were so successful, we forgot their impact due to vanishing diseases."
Bringing a major pseudoscience conspiracist in charge of HHS is a sure way to remember their impact- in the most painful way.

07.07.2025 22:15 β€” πŸ‘ 12    πŸ” 4    πŸ’¬ 1    πŸ“Œ 0
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Summary Table of the massive defunding of biomedical research in the United States
www.nytimes.com/interactive/...

06.07.2025 15:13 β€” πŸ‘ 1556    πŸ” 1014    πŸ’¬ 60    πŸ“Œ 76
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More on this @latimes.com by @niamhordner.bsky.social
www.latimes.com/science/stor...

06.07.2025 15:20 β€” πŸ‘ 122    πŸ” 49    πŸ’¬ 3    πŸ“Œ 0

Benim yazdığım kod pek maintain edilmiyor. Her projeye ayrı, bir seferlik kullanım için yazılıyor.

03.07.2025 15:12 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

Valla artΔ±k kod değil comment yazΔ±yorum Γ§oğunlukla. Bir iki satΔ±r ekleyip Γ§Δ±kartΔ±yorum aralara. Boilerplate kod iΓ§in harika. Debugging iΓ§in de ΓΆyle. 40 satΔ±r hata mesajΔ± okumuyorum, Copilot’a soruyorum hemen. Γ‡ok işe yarΔ±yor. Ama daha low-level kod yazanlar iΓ§in o kadar kullanışlΔ± olmayabilir.

03.07.2025 05:30 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
A meme-style comic panel with three parts. Left: A stylized enhancer with a mutation, surrounded by colored blocks representing functional motifs, a neural network diagram, chromatin accessibility signal traces, and a sequence motif. Two cartoon mouse embryos below show different LacZ reporter activity patterns. Top right: A hand hovers anxiously between two red buttons labeled β€œExperiments” and β€œAI,” with the caption β€œHOW DO ENHANCERS REALLY WORK?” Bottom right: A sweating superhero wipes his forehead, looking stressed about the difficult choice.

A meme-style comic panel with three parts. Left: A stylized enhancer with a mutation, surrounded by colored blocks representing functional motifs, a neural network diagram, chromatin accessibility signal traces, and a sequence motif. Two cartoon mouse embryos below show different LacZ reporter activity patterns. Top right: A hand hovers anxiously between two red buttons labeled β€œExperiments” and β€œAI,” with the caption β€œHOW DO ENHANCERS REALLY WORK?” Bottom right: A sweating superhero wipes his forehead, looking stressed about the difficult choice.

Textbooks: β€œEnhancers are just a bunch of TFBSs”

But how do they REALLY work?

New paper with many contributors here @berkeleylab.lbl.gov, @anshulkundaje.bsky.social, @anusri.bsky.social

A 🧡 (1/n)

Free access link: rdcu.be/erD22

18.06.2025 17:55 β€” πŸ‘ 165    πŸ” 80    πŸ’¬ 2    πŸ“Œ 5
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San Francisco voters urge unity to tackle fentanyl - The Voice of San Francisco Our justice system is facing unprecedented times of polarity. San Francisco watched as ICE protests in Los Angeles erupted into violence and Waymo burnings. Subsequently, our city faced its own violen...

'Even in a city renowned for its bleeding heart, there is a breaking point, a collective exasperation with those who weaponize our compassion to fuel a crisis that claims lives young and old, drawn to our streets by cheap drugs and lax enforcement'

thevoicesf.org/san-francisc...

12.06.2025 15:16 β€” πŸ‘ 2    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
Lauren Weinstein (@lauren@mastodon.laurenweinstein.org) After court order, OpenAI is now preserving all ChatGPT user logs, including deleted chats, sensitive chats, etc.

"After court order, OpenAI is now preserving all ChatGPT user logs, including deleted chats, sensitive chats, etc."

05.06.2025 00:00 β€” πŸ‘ 7    πŸ” 4    πŸ’¬ 1    πŸ“Œ 0
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Terminal Genome Viewer (tgv), written in Rust github.com/zeqianli/tgv

27.05.2025 17:37 β€” πŸ‘ 104    πŸ” 27    πŸ’¬ 3    πŸ“Œ 5

It's not Musk or Bezos who's keeping us from building new housing, building mental health facilities or prosecuting the bippers + drug dealers. It is our elected officials who are responsible, and we have only ourselves to blame for electing them.

20.05.2025 04:43 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Pretty much everything we don't like about SF now -be it the cost of living, homelessness+mental health+fentanyl crisis or property crime- can be traced back to decades of progressive politics.

20.05.2025 04:43 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

We should tax the ultra-rich for sure. But if we don't diagnose the problem correctly, we can never solve it. Our problem is not lack of money. SF spends $1.2B on homelessness annually. What do we have to show for it?

20.05.2025 04:43 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

SF mayors don't have much power. It's the BoS who calls the shots. Past BoSs are responsible for many things that we complain about the city today.

19.05.2025 04:50 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

NIMBYs are not the rich. They're us, the people of SF, who voted for "progressive" politicians such as Aaron Peskin, Dean Preston, etc. SF politics has been dominated by progressives for decades. Let's not blame it on the rich.

19.05.2025 04:03 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

It's the NIMBYism that creates inequality. Artists had to move away because housing is absurdly expensive. It's expensive because we don't build enough. The Tech Boom made it worse, but it by itself is not the root of the problem.

19.05.2025 01:48 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 2    πŸ“Œ 0
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Ring Mountain is lovely. It's a great place to hike in any season. Would be a good to bring along a geologist. 8/end

19.05.2025 01:36 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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There are other rare species here, for example Oakland Star Tulip. 7/n

19.05.2025 01:36 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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Calochortus tiburonensis - Wikipedia

TLM was identified in by a plant enthusiast in 1971. It is endangered and protected by the California Endangered Species Act. 6/n en.wikipedia.org/wiki/Calocho...

19.05.2025 01:36 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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Luckily, I was able to find a better looking one. Doug mentioned that the TLM only grows here because of the unusual geology of the mountain. I guess the plant adapted to the high magnesium content in the serpentine soil and it can't spread elsewhere. 5/n

19.05.2025 01:36 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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They showed me a TML specimen. I was a few weeks too early, though. The flower hadn't bloomed yet -- the plant looked a stalk of grass. But they also pointed me to a trail where there are more of them. 4/n

19.05.2025 01:36 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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Tiburon Mariposa Lili (TML) blooms only for a few weeks a year, starting late May. There were a many wildflowers on the trail, but no TLMs. I was disappointed. Then I came across two Marin Parks volunteers: Doug and Belle. 3/n

19.05.2025 01:36 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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This area is interesting geologically as well as archaeologically. There are large boulders scattered around here some displaying petroglyphs carved by the Miwoks. I wasn't able to spot any though. I need to come back for it. 2/n
www.megalithic.co.uk/article.php?...

19.05.2025 01:36 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

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