SARS-CoV-2 delta and omicron variants alter trophoblast cell fusion and syncytiotrophoblast dynamics: new insights into placental vulnerability
www.nature.com/articles/s41...
@strangviruslab.bsky.social
City St George's, University of London. HCMV, anti-viral drugs, placental infection, transmission, etc etc etc. #JGV Editoral Board. Views my own.
SARS-CoV-2 delta and omicron variants alter trophoblast cell fusion and syncytiotrophoblast dynamics: new insights into placental vulnerability
www.nature.com/articles/s41...
2012 Nobel laureate John Gurdon has died. His work was central to both the development of animal cloning and the possibility of reprogramming cells to a different state. A giant of cell and developmental biology.
www.magd.cam.ac.uk/news/profess...
Fwd: Fwd: βI hope this email finds you wellβ
07.10.2025 08:37 β π 276 π 50 π¬ 7 π 8βMore evidence of the link between herpes viruses and dementia.
The shingles vaccine not only reduces the chance of getting shingles (not worth trying) but also reduces the risk of developing dementiaβ (I hope this translates ok. )
Link below π
This yearβs Nobel Prize in Physiology or Medicine has been awarded to three scientists for discovering a class of immune cells that help to prevent the body from attacking its own tissues
go.nature.com/48QDdAJ
I once had norovirus.
Once was enough.
What took you so longβ¦.?
04.10.2025 06:31 β π 0 π 0 π¬ 0 π 0Hope you are well!
02.10.2025 16:40 β π 0 π 0 π¬ 1 π 0New preprint from our lab, led by our postdocs Dara Annett and Kate Morling in collaboration with Selwood Lab!
We developed a modified cyclosporine, BG147, which enhances lentivector gene therapy transduction, ex vivo in HSPC and in vivo in mouse photoreceptors, by degrading IFITM3. Check it out!
New exciting resource published!! The Viro3D paper is out, describing our comprehensive database of predicted virus protein structures! π»π§¬
Work with @ulad-litvin.bsky.social , @grovearmada.bsky.social , Alex Jack, @bljog.bsky.social , @davidlrobertson.bsky.social
www.embopress.org/doi/full/10....
π¨ New Web Resource Alert! π¨ We're delighted to share Viro3D a database of >85000 viral protein structure predictions from >4400 human & animal viruses.
π viro3d.cvr.gla.ac.uk
π www.embopress.org/doi/full/10....
@molsystbiol.org @cvrinfo.bsky.social @uofgmvls.bsky.social #Virology #AlphaFold π§ͺ π¦
Earlier this year we took our Escape Lab outreach activity on the road, funded by @microbiologysociety.org & @biochemsoc.bsky.social Outreach Grants. We had a blast teaching kids about viruses & the drug discovery process. Check out how Microbiology Society's Adam & Clare got on with Escape Lab!
25.09.2025 11:20 β π 7 π 3 π¬ 0 π 0βMario Draghiβs warning on EU research βrings trueβ It does. Iβm part of a consortium that was deemed fundable yet thereβs no money to fund it. Many others have been there. Europe needs to do better, if we genuinely want to attract colleagues and research topics. But also for those already here.
25.09.2025 11:42 β π 3 π 2 π¬ 1 π 0MAGA/MAHA love to cite his opinions, but he got *at least* $150,000 to be an expert witness in anti-Tylenol lawsuits.
Conflicts of interest donβt bother MAGA/MAGA world at allβin fact, they almost seem to be a requirement (see: Dr Oz selling folinic acid)
π link
www.nytimes.com/2025/09/23/h...
This is huge: βA drug that provides near-perfect protection against H.I.V. with shots just twice a year will be made available at $40 per patient annually in low- and middle-income countries, offering new hopeβ¦ making lenacapavir a realistic choice in countries with constrained resources.β
24.09.2025 11:51 β π 4163 π 1309 π¬ 4 π 152David Baltimore, for much of the past three decades, has been one of my most helpful, thoughtful sources. I wrote an obit about his remarkable career, and I included a few of my interactions with him. www.science.org/content/arti...
09.09.2025 22:42 β π 51 π 20 π¬ 2 π 1@shivkumarlab.bsky.social π ?
10.09.2025 18:06 β π 1 π 0 π¬ 0 π 0Read this, then sign the petition below. Every bit of pressure helps. You can make a difference!
www.change.org/p/demand-rfk...
Obituary for David Baltimore; huge influence in more aspects of virology than can possibly be listed in a post.
www.nytimes.com/2025/09/07/s...
Nature research paper: A nanobody specific to prefusion glycoprotein B neutralizes HSV-1 and HSV-2
go.nature.com/4mZHupC
Yesterday was the 11th anniversary of the biggest scandal of the Obama administration.
29.08.2025 18:35 β π 1097 π 197 π¬ 63 π 28A very special day today, as I look back and remember our trepidation on how this crazy idea of a new pathogen database would go down. Would our work be for naught?
But no! I'm so grateful that we've been able to make a big impact on sequence sharing! Here's to year 2! π₯
Soo.... the last time it was online was April 1 2025 (consistently offline April 4 onwards)
web.archive.org/web/20250401...
My (limited) understanding is that hmpdacc.org is recently run by a team at IGS UMD, and the website being offline may or may not relate to changes at the NIH
Curious about tick virology? Read my latest piece in @uk.theconversation.com where I explain findings of my latest research article www.nature.com/articles/s41...
Hope it will helps people to understand the importance of studying tick and their pathogens #ScienceforAll #WomenInScience #Arbovirose
"Treating the root cause" is a trope abused in alternative/integrative/functional medicine to sow distrust in mainstream medicine.
Ironically, a scientifically implausible βroot causeβ is often treated with pseudoscientific approaches.
H/t @glaucomflecken.bsky.social
hmm I wonder if this might underly some of the sex differences in acute viral haemorrhagic fevers (eg the damage in european hantaviruses manifests as acute renal damage - particularly in young men)
www.nature.com/articles/d41...
Two-year postdoc position available! π¦ π¬
Investigating a COPD drug to see if it can reduce inflammation & tissue remodelling following respiratory virus infection.
Lots of cell culture and primary cell culture, qPCR, microscopy
jobs.surrey.ac.uk/Vacancy.aspx...
An mRNA-based broad-spectrum antiviral inspired by ISG15 deficiency protects against viral infections in vitro and in vivo www.science.org/doi/10.1126/...
15.08.2025 13:42 β π 1 π 2 π¬ 0 π 0This π
Brilliant from @jakescottmd.bsky.social
www.statnews.com/2025/08/13/r...
Pregnancy reduces COVID-19 vaccine immunity against novel variants
www.nature.com/articles/s41...