Funded PhD: Understanding the role of the ribosomal P-stalk in immune responses at University of Bristol on FindAPhD.com PhD Project - Funded PhD: Understanding the role of the ribosomal P-stalk in immune responses at University of Bristol, listed on FindAPhD.com

First ad for a position in my new lab at the University of Bristol! If you are looking for a fully funded PhD in cutting edge science that will be based in a supportive environment, and in a great city, check out the link below!

www.findaphd.com/phds/project...

Every time he does this a calculator somewhere in the country spontaneously bursts into flames

Reaffirming the value of model organisms in training scientific minds - Nature Cell Biology As biomedical research prioritizes human models and translational promise, classic model organisms are increasingly dismissed. Here we argue that they have a lasting value, both in enabling discovery and in cultivating scientific thinking, by training researchers in systems reasoning, integrative thinking and independent inquiry.

Model organisms, in particular non-mammalian model organisms, such as yeast, Caenorhabditis elegans, #Drosophila and zebrafish, have long stood at the centre of biological discovery www.nature.com/articles/s41...

Come work with us!!

Congrats again to this super team!!

A gut-brain axis for aversive interoception drives innate and anticipatory emesis in Drosophila. https://www.biorxiv.org/content/10.1101/2025.10.01.679515v1

Remote control of AMPK via extracellular adenosine controls tissue growth - Nature Cell Biology Zhang et al. demonstrate that AMPK can be activated by signalling metabolite, adenosine, under non-stress conditions during Drosophila development. The intestine regulates adenosine levels, thus, remotely controlling wing disc AMPK activation and growth.

💫NEW: @telemanlab.bsky.social & co demonstrate that #AMPK can be activated by signaling metabolite, #adenosine, under non-stress conditions during #Drosophila development. The intestine regulates adenosine levels, thus, remotely controlling wing disc AMPK activation and growth.
bit.ly/4gX6njF

Passionate about doing a PhD on metabolism in neural stem cells and their niche? The call just opened for applications for a PhD position in our lab @crick.ac.uk in London. Please repost.
tinyurl.com/ysnkdrmw

Excited to share our collaborative PhD project with Adam Dobson (Adam.Dobson@glasgow.ac.uk) on interorgan signalling in the ageing gut. Please contact Adam If you are a highly motivated student wanted to work on a super exciting Fly project.

Many congratulations on this fantastic study.
Very happy to both stories together.

Epithelial GREMLIN1 disrupts intestinal epithelial-mesenchymal crosstalk to induce a wnt-dependent ectopic stem cell niche through stromal remodelling - Nature Communications The authors show that aberrant epithelial GREM1 expression remodels intestinal stroma to form ectopic stem cell niches in mice. Anti-GREM1 reversed these changes, highlighting a potential strategy for...

Finally out! A longstanding project to explore the mechanism behind ectopic crypt formation in polyps when GREM1 is aberrantly expressed in HMPS patients. Turns out it is all to do with stromal remodelling and epithelial-mesenchymal interdependence!
www.nature.com/articles/s41...

We are looking forward to seeing you at the @edrc2025.bsky.social
You can find us
- On Thursday 25th at the workshop: INTERORGAN COMMUNICATION IN THE ERA OF OMICS,
- On Saturday morning 27th @alphyjohn.bsky.social will give a talk in the session stem cells and regeneration
- On poster sessions

I have gotten a bit behind at sharing the lab’s latest work - this paper is now published - check it out! www.cell.com/cell-reports... Long story short: insulin is the major determinant of female fat storage, with a relatively minor effect on males.

Fantastic news congratulations Alex!

Glasgow Cancer Scientist Awarded Prestigious UKRI Future Leaders Fellowship | Glasgow City Of Science & Innovation Alexander Raven, an early career researcher from the School of Cancer Sciences, has been awarded one of UK Research and Innovation’s (UKRI) flagship Future Leaders Fellowships.

🧬 Glasgow researcher Dr Alexander Raven has been awarded a prestigious UKRI Future Leaders Fellowship to advance understanding of how liver cancer develops, with the aim of improving detection and treatment

📍 University of Glasgow
👇 Learn more

glasgowcityofscienceandinnovation.com/glasgow-canc...

Congratulations!!

📢Are you a talented #ECR looking to start your independent lab in state-of-the-art cancer research facilities?

Join the CRUK Scotland Institute & @uofgcancersciences.bsky.social as a Junior Group Leader!

👉Apply here: www.crukscotlandinstitute.ac.uk/careers/grou...

📅Closing date: 10 October 2025

Assistant or Associate Professor - Urbana, Illinois job with University of Illinois, School of Molecular and Cellular Biology | 12843703 Tenure-track Assistant or Associate Professor Department of Cell and Developmental Biology School of Molecular and Cellular Biology University of I...

We are hiring! The University of Illinois Urbana-Champaign Department of Cell and Developmental Biology is hiring a faculty member in the area of Aging, broadly defined. Come join us! Deadline is soon! www.nature.com/naturecareer...

A though provocative idea potentially connecting cell metabolic state and sensitivity to mechanical stress (and thus potentially relevant for cell competition)

Energy deficiency selects crowded live epithelial cells for extrusion - Nature Crowded epithelial cells with the least energy and membrane potential are selected for extrusion.

Epithelial crowding drives membrane depolarisation by ENaC/Na+ entry which triggers rapid volume loss, piezo activation and live cell extrusion. Importantly, low intracellular ATP primes cells for live extrusion by preventing the restoring of mb polarisation.

www.nature.com/articles/s41...

Sex-biased expression of enteroendocrine cell-derived hormones contributes to higher fat storage in Drosophila females https://www.biorxiv.org/content/10.1101/2025.09.09.675263v1

📢 We are looking for a sandwich student to join the lab of @irenemiguel-aliaga.bsky.social at the @crick.ac.uk for a 12-month placement starting July 2025!

Interested in how the 🐁 gut changes during pregnancy? Check the project and eligibility criteria here: www.crick.ac.uk/careers-stud...

UK undergrads, apply to this programme for your chance to work with the one and only Dr ‪Amélie Joly‬!

Fantastic and so richly deserved!

The Company of Biologists 100 logo to the left and QR code to the right. Portrait of Owen Sansom to the left, text to the right 100 extraordinary biologists Owen Sansom Owen Sansom is a DMM Monitoring Editor and co-organiser of the 2024 DMM Journal Meeting. Owen is the Director of CRUK Scotland Institute, UK, where his research has been key in determining the molecular hallmarks of colorectal cancer and defining the roles of APC, WNT signalling and intestinal stem cells in tumourigenesis. #100biologists #biologists100

We are highlighting Owen Sansom, @dmmjournal.bsky.social Monitoring Editor and co-organiser of the 2024 DMM Journal Meeting, as an extraordinary biologist this week. #100biologists @osansom.bsky.social @cruk-si.bsky.social

The first September issue is live.

www.embopress.org/toc/14693178...

The cover features work by Cassie Clarke @cassiejclarke.bsky.social @cruk-si.bsky.social and co-workers showing that UPP1 supports #metastasis by altering #immune and ECM landscapes.

-> www.embopress.org/doi/full/10....

Synaptic targets of circadian clock neurons influence core clock parameters A neuron type downstream of circadian pacemakers regulates daily sleep and activity timing in Drosophila.

New publication from our lab, in Science Advances:

Synaptic targets of circadian clock neurons influence core clock parameters

www.science.org/doi/10.1126/...

Don't miss our next webinar by Zoi Diamantopoulou on "Timing the perfect strike: Using circadian rhythms to target metastasis" - September 22, 2025 - more details and register here: metastasis-research.org/2025/09/11/z...

Why would anyone want to be a scientist?

"Doing good science requires the utmost exertion of body, mind and spirit, yet is consistently filled with failure and rejection."

journals.biologists.com/jcs/article/...

Formal application for 2 posts-doctoral research positions in the lab can now be submitted here:

www.jobs.gla.ac.uk/job/research...