Dominique Langin

Persistance dans le tissu adipeux d’une mémoire épigénétique de l’obésité après perte de poids - Le Diabète dans tous ses états Toutes les personnes ayant perdu du poids, via des mesures hygiéno-diététiques, un traitement médical ou une chirurgie bariatrique, le savent que trop bien : elles risquent rapidement de reprendre du ...

Persistance dans le tissu adipeux d’une mémoire épigénétique de l’obésité après perte de poids
A lire sur 'Le diabète dans tous ses états'
www.le-diabete-dans-tous-ses-etats.precidiab.org/obesite/pers...

NK2R control of energy expenditure and feeding to treat metabolic diseases - Nature In mouse and nonhuman primate models, treatment with selective, long-acting neurokinin 2 receptor agonists aids weight loss by suppressing appetite and increasing energy expenditure, as well as b...

First post! Didn't see this study on @bsky.app.

From @zgerharthines.bsky.social group identifying neuronal NK2R as a regulator of feeding/hunger & energy expenditure, and demonstrating the efficacy of a small molecule agonist in non-human primates for weight loss.

www.nature.com/articles/s41...

Adipose tissue retains an epigenetic memory of obesity after weight loss - Nature Stable epigenetic changes indicate the existence of an obesogenic memory in mouse adipocytes that primes cells for pathological responses in an obesogenic environment and potentially contributes to th...

🧬 New in @Nature: Our team found that fat cells keep a “memory” of their previous obese state even after weight loss, helping explain why maintaining weight loss is so challenging. Excited to share this work!!

www.nature.com/articles/s41...

Hi Erik. I wish to be added to the Science feed. Orcid number: orcid.org/0000-0002-2669-7825
Great job and hope the community will continue growing. Thanks

A study from our lab @ I2MC Toulouse shows the importance of fat degradation in brown fat to generate heat. Fruitful collaboration with Prof.  Carpentier at CHU Sherbrooke. Published in Cell Metab dlvr.it/TGGbFJ 🧪

Cold-induced thermogenesis requires neutral-lipase-mediated intracellular lipolysis in brown adipocytes This study shows that intracellular lipolysis in brown adipose tissue (BAT) is essential for cold-induced thermogenesis. By using a mouse model with ATGL/HSL deletion in BAT, researchers revealed impa...

A new study led by Prof. Dominique Langin at I2MC Toulouse sheds light on the importance of fat degradation in brown fat to generate heat. Fruitful collaboration with Prof. Carpentier team at CHU Sherbrooke. Insight on how to burn calories published in Cell Metabolism.
dlvr.it/TGGbFJ