Lee Roberts

Congratulations to Amanda MacCannell on her Michael J Rennie Oral Communication Prize @physoc.bsky.social Physiology of Obesity: From Mechanisms to Medicine Meeting held in Nottingham. Presenting her @thebhf.bsky.social funded research.

Anna Malicka, Aysha Ali, Amanda D. V. MacCannell and @leerobertslab.bsky.social (@universityofleeds.bsky.social) explore the the inter-organ signalling mechanisms of brown and beige adipose tissue-derived metabokines and lipokines.

📜 buff.ly/isAId5k

Moving on to metabokines in obesity with @leerobertslab.bsky.social

Application of CIBERSORTx and BayesPrism to deconvolution of bulk RNA-seq data from human myocardium and skeletal muscle RNA-sequencing (RNA-seq) is an important tool to explore molecular mechanisms of disease. Technological advances mean this can be performed at the single-cell level, but the large sample sizes needed ...

Application of CIBERSORTx and BayesPrism to deconvolution of bulk RNA-seq data from human myocardium and skeletal muscle: Heliyon www.cell.com/heliyon/full...

Paracrine role of endothelial IGF-1 receptor in depot-specific adipose tissue adaptation in male mice - Nature Communications Here the authors show that lowering IGF-1R levels in endothelial cells improves insulin sensitivity, boosts energy use, and supports beneficial changes in adipose tissue, offering insights into potent...

Metabolite-mediated inter-tissue signalling. Led by Jane Luk & Mark Kearney @unileedsnews.bsky.social in @naturecomms.bsky.social we identify malonic acid as an IGF1R-regulated endothelial-to-adipocyte metabokine mediating adipose metabolism. Great start to 2025.
www.nature.com/articles/s41...

Yesterday I had the huge pleasure of delivering my Inaugural Lecture as Professor @universityofleeds.bsky.social in front of my family, friends, colleagues and group. A huge thanks to them for making this possible. I’m excited to see what our future science holds.

Congratulations to Dr AlMutairy for her PhD viva today. Very proud. Thank you very much Dr Emer Fitzpatrick and Dr David Buckley for examining. @leerobertslab.bsky.social and @richard Cubbon co supervisors @envleeds.bsky.social @licamm.bsky.social

Brown and beige adipose tissue‐derived metabokine and lipokine inter‐organ signalling in health and disease Adipose tissue has an established endocrine function through the secretion of adipokines. However, a role for bioactive metabolites and lipids, termed metabokines and lipokines, is emerging in adipos...

Congratulations to 1st year PhD students Anna Malicka and Aysha Ali and Fellow Amanda MacCannell on publication of their review in #ExpPhys on brown adipose tissue-derived bioactive metabolite interorgan signalling. #brownadipose #metabokines
physoc.onlinelibrary.wiley.com/doi/10.1113/...

Job Opportunity at University of Leeds: Postdoctoral Research Fellow in Adipose Tissue – Cardiac Crosstalk in Cardiovascular Disease Are you a postdoctoral researcher with a keen interest in cardiometabolic molecular physiology and metabolism in health and disease?  Are you interested in how adipose tissue communicates with the hea...

We are hiring a postdoctoral research associate in adipose tissue - cardiac crosstalk to join my lab @UoL_LICAMM @LeedsMedHealth Experience of animal models of cardiovascular disease - positive. Job description and how to apply here: jobs.leeds.ac.uk/Vacancy.aspx...

Thanks Claire. No better place to receive a rejection!

Also perhaps a good time to rewatch The Big Lebowski!

It’s grant rejection Monday here today. All part of academic science of course, and we should normalise it, but we all know it’s disappointing. So I’m interested to know, what’s the best way people get over #grantrejection?

Sharing again as I have added a at least 20 newbies and people how I just found out were here. Just need to get that Giles Yeo over here now go.bsky.app/NRoqMvp

Thanks @chillslincoln79.bsky.social I’ve crossed the Rubicon and hoping for some balanced scientific discussions over this side.

Starting afresh on this platform. We are a research group in the School of Medicine @universityofleeds.bsky.social our interests include #metabolism, #adipose, #muscle in a setting of #cardiometabolicdisease #diabetes #obesity #heartfailure and #exercise.