New cocktail πΉ in town - in collaboration with @benlehner.bsky.social : Massive combinatorial mutagenesis + amyloid kinetics selection + thermodynamic modelling showing us the portrait π¨ of an amyloid transition state. Read about it in this great thread:
12.06.2025 13:30 β π 11 π 2 π¬ 1 π 0
Solving the many mysteries of amyloids π§©π§¬, next up at #VariantEffect25: @marianomartin.bsky.social from @bennibolo.bsky.social Lab presents:
Deep mutagenesis reveals the interplay between RIPKs amyloid nucleation and protein activity
23.05.2025 07:58 β π 8 π 6 π¬ 0 π 0
@juliadiumenge.bsky.social at #VariantEffect25
22.05.2025 10:06 β π 16 π 2 π¬ 0 π 1
@mattcoelho.bsky.social at #VariantEffect25
22.05.2025 08:09 β π 7 π 3 π¬ 0 π 0
VSS people are always hungry for more heatmaps discussion! (and burgers!) #VariantEffect25
22.05.2025 07:07 β π 5 π 1 π¬ 0 π 0
@nickywhiffin.bsky.social at #VariantEffect25
21.05.2025 10:24 β π 17 π 4 π¬ 0 π 1
Group Leader
The Genome Function Laboratory
The Francis Crick Institute, London
Scientist & Communicator. Fascinated by cells across scales - π, π¬and β³. PI @GIMM, EMBO member. Former Director @IGC, PD @Cambridge University, PhD @UCL/IGC. My motto: "Science from all for all". Mom of 2 wonderful girls. Views are my own.
Postdoc in Lehner lab @sangerinstitute | PhD @sangerinstitute @Cambridge_Uni | BSc @miptru π·πΊπ¦π²
Genomics | Synthetic Biology | Immunology | Reproduction
All views and opinions expressed are my own.
Researching somatic evolution at the University of Cambridge and Wellcome Sanger Institute. Also a scientific illustrator.
Professor of Biochemistry, Uppsala University. Views are my own.
Protein domains, disorder and interactions.
Opinions here are my own.
Day job: Professor and Chair,
Computational & Systems Biology,
University of Pittsburgh School of Medicine
https://rothlab.csb.pitt.edu/
Systematically testing impacts of genetic change & mapping protein interaction dynamics
Postdoc at @crg.eu Barcelona,
previously PhD at Cambridge University
Genomics | Mutational Scanning | Molecular Evolution π§¬π±
www.pyrisentinel.eu β°οΈπ www.puntseq.com
Digests proteins. High-throughput protein biophysics and design, Northwestern University. www.rocklinlab.org
Stanford BioE, Genetics & Sarafan ChEM-H. Chan-Zuckerberg Biohub Investigator. Our lab develops and applies microfluidic assays for high-throughput biophysics and biochemistry.
all our switches
π www.allox.bio
Co-founder & CTO @alloxbio.bsky.social / deep mutagenesis / open science / degrowth / anti-imperialism / tax the rich / my views / him
π www.allox.bio
music/arts addicted currently playing with genes, cells and proteins in bcn | PhD student at Institute for Bioengineering of Catalunya
https://linktr.ee/ireneminovas
En Bluesky desde 2008. De gira en http://www.facudiaz.net
Cancer Research UK Career Development Fellow at the Wellcome Sanger Institute - gene editing - drug resistance - cancer
PhD student at the Institute for Bioengineering of Catalonia (IBEC) | Deep mutational scanning
PhDing at the Sanger Institute, i'm evolving every day
πΌ isabellezane.bio