Tharin Blumenschein 's Avatar

Tharin Blumenschein

@tblumens.bsky.social

Protein NMR spectroscopy, teaching, and random opinions

490 Followers  |  601 Following  |  4 Posts  |  Joined: 02.10.2023  |  1.9774

Latest posts by tblumens.bsky.social on Bluesky

Preview
The UK is no longer offering COVID vaccines to pregnant women โ€“ hereโ€™s why that might be a bad idea From spring 2025, pregnant women will no longer be eligible for free COVID vaccines in the UK.

This is a fuller article on vaccines and pregnancy I wrote after England made decision to remove free access in autumn

28.05.2025 07:51 โ€” ๐Ÿ‘ 43    ๐Ÿ” 14    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 2
Post image

In a world of Matts, be a Derek.

10.03.2025 19:44 โ€” ๐Ÿ‘ 31915    ๐Ÿ” 8037    ๐Ÿ’ฌ 458    ๐Ÿ“Œ 258
Video thumbnail

Structural biology is in an era of dynamics & assemblies but turning raw experimental data into atomic models at scale remains challenging. @minhuanli.bsky.social and I present ROCKET๐Ÿš€: an AlphaFold augmentation that integrates crystallographic and cryoEM/ET data with room for more! 1/14.

24.02.2025 12:22 โ€” ๐Ÿ‘ 137    ๐Ÿ” 60    ๐Ÿ’ฌ 6    ๐Ÿ“Œ 5

After some years in the drawer, our work on the dynamics of the Phytophthora effector Avr3a11 is out on Biochemistry! This WY domain shows flexibility thatโ€™s likely important for function, and a general property. pubs.acs.org/doi/10.1021/...

24.02.2025 17:21 โ€” ๐Ÿ‘ 3    ๐Ÿ” 2    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Preview
Probing the Function of RNA Structural Elements in the FMDV Genome using Biophysical and Genetic Approaches at The Pirbright Institute on FindAPhD.com PhD Project - Probing the Function of RNA Structural Elements in the FMDV Genome using Biophysical and Genetic Approaches at The Pirbright Institute, listed on FindAPhD.com

๐Ÿšจ I'm delighted to announce a fully-funded PhD studentship (October 2025 entry) in collaboration with the Pirbright Institute.

Are you interested in FMDV genome replication and packaging? Fascinated by structure and RNA-protein interactions? More info here:

www.findaphd.com/phds/project...

20.01.2025 11:12 โ€” ๐Ÿ‘ 15    ๐Ÿ” 14    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 1
Post image

Daydreaming in the lab is fine provided you've turned off your hot plate and not left anything oxidising

11.01.2025 12:06 โ€” ๐Ÿ‘ 35    ๐Ÿ” 7    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

PSA to share with folks you know: Anyone migrating to or already on BSky will be happier if they use the plugin to find their twitter mutuals. One is the Sky Follower Bridge extension that works on Chrome, Firefox, Edge and others. Pass it on! ๐Ÿฆ‹

07.01.2025 05:07 โ€” ๐Ÿ‘ 104    ๐Ÿ” 27    ๐Ÿ’ฌ 7    ๐Ÿ“Œ 2
Experience Postgrad Life Sciences | Enhancing diversity among life scientists of the future

โ€ผ๏ธDeadline 16th January 2025โ€ผ๏ธApplications are open for the 2025 Experience Postgrad Life Sciences programme. Paid 8-week summer internships aimed to enhance diversity among life scientists of the future!! @cambridgebiosci.bsky.social @corpuscambridge.bsky.social www.exppg.lifesci.cam.ac.uk

07.01.2025 06:50 โ€” ๐Ÿ‘ 3    ๐Ÿ” 7    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Preview
PhD studentship: Structural and functional characterisation of mycobacterial outer membrane proteins at Newcastle University on FindAPhD.com PhD Project - PhD studentship: Structural and functional characterisation of mycobacterial outer membrane proteins at Newcastle University, listed on FindAPhD.com

First post of the year to mark my return from maternity leave :) Excited to share the first open PhD position in my group.
Deadline end of February.
Please spread the word. www.findaphd.com/phds/projectdetails.aspx?PJID=181239

06.01.2025 21:14 โ€” ๐Ÿ‘ 41    ๐Ÿ” 34    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 3
Open recruitment for the Tornini Lab
Department of Integrative Biology and Physiology & Institute for Society and Genetics
Hispanic Serving Institution Infrastructure Initiative
University of California, Los Angeles (UCLA)
www.torninilab.org
We are a new developmental, cell, and molecular biology lab interested in understanding the
genetics of vertebrate neurodevelopment.
We use genome engineering, single-cell technologies, behavioral analyses, pharmacological
profiling, confocal imaging, genomics, and computational biology using the vertebrate
zebrafish (Danio rerio) system and other models (like sea lamprey) for evolutionary studies.
Our work is driven by curiosity, independence and teamwork, fun, a sense of urgency, and a
desire to understand how networks of genes regulate brain and organismal development. This
work can help us better understand basic mechanisms of what happens in human
developmental disorders or diseases and can inform novel therapeutic strategies.
We are recruiting across all levels.
Our lab works in multiple complementary areas (please see below).
Weโ€™re looking to match motivated people with what motivates them in a supportive and
engaging environment.
We are recruiting staff research scientists (1-2 years after undergrad+), graduate students (open
rotation positions), postdocs, and other positions as relevant.
While multiple of our projects are already funded, we strongly support candidates to identify
and apply for your own fellowships/grants with the full mentorship and resources of the lab.
Like our research? Think you might be a good fit?
Consider joining us!
For more information, please visit our website, the next page, or contact Val at: vtornini at ucla
dot edu
UCLA is an equal opportunity employer.

Open recruitment for the Tornini Lab Department of Integrative Biology and Physiology & Institute for Society and Genetics Hispanic Serving Institution Infrastructure Initiative University of California, Los Angeles (UCLA) www.torninilab.org We are a new developmental, cell, and molecular biology lab interested in understanding the genetics of vertebrate neurodevelopment. We use genome engineering, single-cell technologies, behavioral analyses, pharmacological profiling, confocal imaging, genomics, and computational biology using the vertebrate zebrafish (Danio rerio) system and other models (like sea lamprey) for evolutionary studies. Our work is driven by curiosity, independence and teamwork, fun, a sense of urgency, and a desire to understand how networks of genes regulate brain and organismal development. This work can help us better understand basic mechanisms of what happens in human developmental disorders or diseases and can inform novel therapeutic strategies. We are recruiting across all levels. Our lab works in multiple complementary areas (please see below). Weโ€™re looking to match motivated people with what motivates them in a supportive and engaging environment. We are recruiting staff research scientists (1-2 years after undergrad+), graduate students (open rotation positions), postdocs, and other positions as relevant. While multiple of our projects are already funded, we strongly support candidates to identify and apply for your own fellowships/grants with the full mentorship and resources of the lab. Like our research? Think you might be a good fit? Consider joining us! For more information, please visit our website, the next page, or contact Val at: vtornini at ucla dot edu UCLA is an equal opportunity employer.

Novel micropeptides in vertebrate neurodevelopment
 Using zebrafish models, we
ask: what are these proteins; what are their functions in neurodevelopment; what are other
โ€œignoredโ€ or โ€œdark proteomeโ€ genes we are missing; and what can they reveal about human
neurodevelopmental disorders or diseases?
Chromatin regulators in vertebrate development and behavior
A growing group of evolutionarily conserved chromatin regulators have been identified as
genes linked with neurodevelopmental disorders, such as autism. In many cases, patients may
struggle with co-occurring conditions that impact daily life in childhood and adulthood,
including seizures, sleeplessness or sleep disruptions, and autoimmune disruptions. How do
these genes work to establish and maintain neural cell types during development, and in turn
shape circuits during early critical periods, including interactions with the environment, to
establish organismal physiological processes? 

Non-neuronal regulation during development and aging
Non-neuronal cell types, including oligodendrocytes and microglia, have emerged as key
players in shaping neurodevelopment and into adulthood. How are the cellular, molecular, and
physiological dynamics of these cell types in developing and aging brains affected in mutant
genetic models linked to neurodevelopmental disorders? Can we target these cells to
modulate neural dysregulation and resulting behaviors in these mutant models?

Evolution of vertebrate brain cell states
We seek to understand the principles of how novel genes co-evolve with the emergence of
neural cell types found only in vertebrates.
We use cross-species genomics and functional approaches with the jawless vertebrate model,
sea lamprey, to elucidate the roles of vertebrate-specific genes on the gene regulatory
networks.
Bioethics, neuroethics, and genetics
We seek to integrate evidence-based methods throughout our projects to investigate and address bioethical considerations in this research domain.

Novel micropeptides in vertebrate neurodevelopment Using zebrafish models, we ask: what are these proteins; what are their functions in neurodevelopment; what are other โ€œignoredโ€ or โ€œdark proteomeโ€ genes we are missing; and what can they reveal about human neurodevelopmental disorders or diseases? Chromatin regulators in vertebrate development and behavior A growing group of evolutionarily conserved chromatin regulators have been identified as genes linked with neurodevelopmental disorders, such as autism. In many cases, patients may struggle with co-occurring conditions that impact daily life in childhood and adulthood, including seizures, sleeplessness or sleep disruptions, and autoimmune disruptions. How do these genes work to establish and maintain neural cell types during development, and in turn shape circuits during early critical periods, including interactions with the environment, to establish organismal physiological processes? Non-neuronal regulation during development and aging Non-neuronal cell types, including oligodendrocytes and microglia, have emerged as key players in shaping neurodevelopment and into adulthood. How are the cellular, molecular, and physiological dynamics of these cell types in developing and aging brains affected in mutant genetic models linked to neurodevelopmental disorders? Can we target these cells to modulate neural dysregulation and resulting behaviors in these mutant models? Evolution of vertebrate brain cell states We seek to understand the principles of how novel genes co-evolve with the emergence of neural cell types found only in vertebrates. We use cross-species genomics and functional approaches with the jawless vertebrate model, sea lamprey, to elucidate the roles of vertebrate-specific genes on the gene regulatory networks. Bioethics, neuroethics, and genetics We seek to integrate evidence-based methods throughout our projects to investigate and address bioethical considerations in this research domain.

We are openly recruiting at all levels at the Tornini Lab at the University of California, Los Angeles (UCLA)!
Please share with your networks. For more information, please check the info below, visit www.torninilab.org, or email me directly at vtornini at ucla dot edu. Thank you in advance!

09.12.2024 20:48 โ€” ๐Ÿ‘ 34    ๐Ÿ” 29    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 2

Two stages of writing:

1) This shouldn't take too long
2) Oh no

04.12.2024 19:36 โ€” ๐Ÿ‘ 37670    ๐Ÿ” 7138    ๐Ÿ’ฌ 571    ๐Ÿ“Œ 790

Bloody hell.

26.11.2024 13:22 โ€” ๐Ÿ‘ 9    ๐Ÿ” 5    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Preview
MRC DiMeN Doctoral Training Partnership: Investigating regulatory role of transposable elements in human retina during development and aging. at Newcastle University on FindAPhD.com PhD Project - MRC DiMeN Doctoral Training Partnership: Investigating regulatory role of transposable elements in human retina during development and aging. at Newcastle University, listed on FindAPhD....

I have a Fully funded @DiMeN_DTP PhD available currently!

Exploring transposable elements in the human retina and their role in aging & neurodegeneration!

www.findaphd.com/phds/project...

๐Ÿ”ฌ Fully computational project
๐Ÿงฌ Bioinformatics & single-cell
focus

Get in touch for an informal chat

20.11.2024 06:39 โ€” ๐Ÿ‘ 5    ๐Ÿ” 6    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
LinkedIn This link will take you to a page thatโ€™s not on LinkedIn

We are hiring postdoctoral associates for lnkd.in/ePm4h4pE Project in collaboration w Mario Motta IBM lnkd.in/e6qpbUSb on Localized Quantum Chemistry Algorithms for Quantum Computers. LASSCF will be integrated with use sample-based quantum diagonalization, recently developed by Mario and IBM

19.11.2024 19:33 โ€” ๐Ÿ‘ 19    ๐Ÿ” 10    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 1

Bluesky tip for newbies: Bluesky has no real algorithm. Likes here do nothing but show the poster that you enjoyed their content.

That kindness is always going to be appreciated by creators, but if you want to help to boost something here, you have to repost it so others see it. ๐Ÿ™‚

18.11.2024 10:27 โ€” ๐Ÿ‘ 26534    ๐Ÿ” 9226    ๐Ÿ’ฌ 20    ๐Ÿ“Œ 12

Oops - I guess this is a problem without any kind of verification process on here yetโ€ฆ

19.11.2024 08:39 โ€” ๐Ÿ‘ 11    ๐Ÿ” 1    ๐Ÿ’ฌ 2    ๐Ÿ“Œ 2

I am about to be recruiting two post-docs to work on cryoEM and cryoET of amyloid aggregates... Anyone interested please drop me a line while the wheels of our HR department turn.............

18.11.2024 15:09 โ€” ๐Ÿ‘ 63    ๐Ÿ” 52    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 4
From explainxkcd - "The periodic table is used to arrange chemical elements based on their properties. This comic groups them together into regions with labels humorously reflecting their properties, characteristics, or uses."

https://www.explainxkcd.com/wiki/index.php/2913:_Periodic_Table_Regions

From explainxkcd - "The periodic table is used to arrange chemical elements based on their properties. This comic groups them together into regions with labels humorously reflecting their properties, characteristics, or uses." https://www.explainxkcd.com/wiki/index.php/2913:_Periodic_Table_Regions

Periodic table regions (xkcd) #chemistry ๐Ÿงชโš’๏ธ

19.11.2024 05:51 โ€” ๐Ÿ‘ 143    ๐Ÿ” 32    ๐Ÿ’ฌ 2    ๐Ÿ“Œ 1
stable aminal vs. stable animal

stable aminal vs. stable animal

Do not confuse...

16.11.2024 21:36 โ€” ๐Ÿ‘ 175    ๐Ÿ” 29    ๐Ÿ’ฌ 4    ๐Ÿ“Œ 5
Turn on alt text reminder accessibility setting

Turn on alt text reminder accessibility setting

If you keep forgetting alt text, this setting is for you.

It's awesome!

10.11.2024 14:28 โ€” ๐Ÿ‘ 915    ๐Ÿ” 457    ๐Ÿ’ฌ 37    ๐Ÿ“Œ 72

Hey, thatโ€™s me! Please do spread the word about this project and get in touch if youโ€™re interested in finding out more.
XH-๐Ÿฅง interactions are the best!

14.11.2024 18:41 โ€” ๐Ÿ‘ 9    ๐Ÿ” 7    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Preview
Professor of RNA Biology and Molecular Genetics (tenure track/tenure) University of California, Irvine is hiring. Apply now!

Our department at UC Irvine is recruiting for a tenure-track position in RNA biology! Assistant or Associate level, any area of RNA biology including in microbiology are encouraged to apply. Come join our vibrant research community in SoCal!

recruit.ap.uci.edu/JPF09320

13.11.2024 20:15 โ€” ๐Ÿ‘ 84    ๐Ÿ” 87    ๐Ÿ’ฌ 2    ๐Ÿ“Œ 3

I tried that link (with my details instead) and found out Iโ€™m blocked by one person. Now Iโ€™m curious whyโ€ฆ

14.11.2024 08:57 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 2    ๐Ÿ“Œ 0

Hi everyone! So exciting to see all the people joining! I donโ€™t post very often, but Iโ€™ll try to make it worthwhile to all the new followers. Loving this new community!

13.11.2024 23:12 โ€” ๐Ÿ‘ 2    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Preview
The Uncertain Future of the Duke Herbarium: Impact on Botanical Research and Conservation Efforts The closure of the Duke Herbarium has raised concerns in the scientific community about the future of botanical research and the preservation of scientific resources. Learn more about the impact and i...

medriva.com/health/envir...

"The facility, which has been instrumental in studying plant diversity and evolution for over 180 years, is set to close due to budget cuts and a decline in staff."

15.02.2024 01:10 โ€” ๐Ÿ‘ 15    ๐Ÿ” 6    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 1

Not something I need, but my impression is that there are always plenty of unoccupied spaces at Biophysical Society meetings. Are those good enough? Iโ€™d be interested to know too.

02.02.2024 20:48 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

Last chance to apply to join us at the LMB for a PhD to explore archaeal cell division and the archaeal origins of eukaryotes: www2.mrc-lmb.cam.ac.uk/students/int...

03.12.2023 10:41 โ€” ๐Ÿ‘ 2    ๐Ÿ” 9    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 1

PhD studentship with myself and Ed Feil at the University of Bath looking at the evolution and epidemiology of plasmids - in particular looking at plasmid fusions/hybrids/recombinants. Lots of fun bioinformatics! Open to UK or international students.
#microsky
www.findaphd.com/phds/project...

18.10.2023 16:17 โ€” ๐Ÿ‘ 48    ๐Ÿ” 56    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 2

@tblumens is following 20 prominent accounts