Mathieu Lepas

Endoplasmic reticulum–mitochondria contacts are prime hotspots of phospholipid peroxidation driving ferroptosis - Nature Cell Biology Sassano et al. identify endoplasmic reticulum–mitochondria contact sites as the intracellular location where phospholipid peroxidation first occurs to promote ferroptosis. Manipulating these contact s...

🍹@mariamls.bsky.social et al. identify ER–mitochondria contact sites as the intracellular location where phospholipid peroxidation first occurs to promote ferroptosis. Manipulating these contact sites dictates #ferroptosis sensitivity in #BreastCancer. @agostinislab.bsky.social
bit.ly/4l93AUW

✨En juillet, le Tour de France des jeunes de la SFM prend des vacances bien méritées et s'arrête sur l’ile paradisiaque de la Nouvelle Calédonie, pour y recontrer Grégoire Davignon, Jeune Docteur de l’IPNC! Envie d’en savoir plus sur son parcours et ses travaux fascinants ? : bit.ly/3IOcKce

Ce mois-ci, c’est Manon de Strasbourg qui vous présente son article coup de ❤️ du ReJMiF : Shigella sort ses SPATEs ! Cette bactérie pathogène produit des enzymes capables de cliver la protéine C3, un élément clé du système immunitaire. Foncez lire l’article de Debande et al. ! bit.ly/46xBVtl

Fungal infections are getting harder to treat The fungus Aspergillus fumigatus tops the World Health Organization's list of worrying fungal diseases. It's growing increasingly resistant to the first-line drug used to treat it.

Fungal infections are getting harder to treat. The fungus Aspergillus fumigatus tops the World Health Organization's list of worrying fungal diseases. It's growing increasingly resistant to the first-line drug used to treat it.
www.nbcnews.com/health/healt...

Marre des galères informatiques ?
🚀 Venez découvrir durant la session Jeunes comment l'IA et d'autres outils informatiques peuvent transformer votre quotidien.
📅 26 septembre 🚩 Congrès #Microbe2025

We are currently hosting a Research Topic at Frontiers in Cellular and Infection Microbiology (IF 4.8).

🦠🔬👩‍🔬 "Immunometabolic Circuits in Host-Pathogen Interaction".

Article submission has been extended to December 22nd!

www.frontiersin.org/research-top...

Ce mois-ci, c’est Thomas qui vous propose l’article coup de ♥️ du ReJMiF : un mécanisme fascinant où le rhinovirus humain 16 active la GTPase ARL5b, empêchant les macrophages de digérer les bactéries et régulant la sécrétion virale 🦠 Foncez lire les travaux de Suzanne Faure‑Dupuy 👉 bit.ly/446O3zY

⚠️Besoin d'un financement pour Microbes 2025 ?
La SFM te propose 2 bourses :
BOURSE DE VOYAGE 🚈 & BOURSE JEUNE REPORTER 🎤
⏳Candidatures avant le 31 juillet et le 31 août

Profite d'un remboursement de tes billets de train + hébergement ! 💵💸
▶️infos/candidatures : www.alphavisa.com/sfm/2025/fr/...

🚨 Attention ! Les candidatures pour le Prix de thèse, c’est jusqu’à demain ☀️

✨En juin, notre Tour de France passe par Montpellier, pour y rencontrer @noemieclaveyroles.bsky.social, doctorante au sein de l’unité DIGIMI. Elle travaille sur les interactions entre la bactérie Xenorabdus et le nématode. Envie d’en savoir plus sur son parcours et ses travaux ? bit.ly/3Tfh0DF

From lab safety to green practices: morning sessions sparked valuable input and ideas. #ICVSRetreat2025

🚨Our latest review in Thorax about the impact of climate change focusing on fungal pathogens in Europe 🌍

A truly enjoyable collaboration with Sarah Sedik @germhuntermd.bsky.social @martinhoenigl.bsky.social and @mbottery.bsky.social

thorax.bmj.com/content/earl...

@icvs-uminho.bsky.social

Title : “A toxic relationship : When the fungus meets its new gal” by Inês Pereira, Go and vote ✨

www.instagram.com/p/DKzaltPtPu...

Participez à la 6e Journée Jeunes Chercheur·se·s en mycologie, le 30 juin au CHU de Lille. Ateliers, échanges et concours (communication orale et thèse en 180 s). Gratuit sur inscription : forms.gle/qK24a9dobNnL... @sfmm-myco.bsky.social

📢 ICVS Student Seminar | Today, 1 PM
🎤 Cátia Rodrigues on "Unveiling the contribution of itaconate to pulmonary granulomatous inflammation in sarcoidosis"
📍 Auditorium A0.02, School of Medicine, UMinho
Don’t miss it!

Very nice time spent with our colleagues and friends Rosely Zancopé… | Aude STURNY LECLERE Very nice time spent with our colleagues and friends Rosely Zancopé, Dayvison Freitas, Rodrigo De Almeida Paes & Priscila Marques de Macedo at INI/Fiocruz - Instituto Nacional de Infectologia Evan...

www.linkedin.com/posts/aude-s...

✨En avril, le Tour de France des jeunes de la SFM passe par Paris !✨ Venez découvrir les travaux d'Alexandra Bouyssi, post-doctorante à l’IMRB ! Elle étudie les interactions entre le champignon Aspergillus et la bactérie Stenotrophomonas 🍄🧫 Pour en savoir plus 👉 bit.ly/4dyrmYi

A single-cell spatial chart of the airway wall reveals proinflammatory cellular ecosystems and their interactions in health and asthma - Nature Immunology Here, the authors use single-cell spatial transcriptomics to profile the airway wall landscape in health and during asthma. Discrete proinflammatory ecosystems containing alarmins, chemokines and a un...

🚨 We did it! Our latest work—led by my lab and the @lloydlab.bsky.social is now published in Nature Immunology! 🎉

Using single-cell spatial transcriptomics, we provide the first map of the airway wall.

🔗 www.nature.com/articles/s41...

#spatialbiology #asthma #mastcells #lungimmunology

📣 ICVS Advanced Seminars

🗓️ Thursday, May 22 at 12h
📍 Auditorium A0.03 – School of Medicine, UMinho

🎙️ Hélder Novais-Bastos
🧬 "Decoding the host-environment crosstalk in pulmonary fibrosis: advancing precision medicine"

Don’t miss this session on precision medicine and pulmonary fibrosis!

🔬✨ National Scientist’s Day ✨🔬
Today we celebrate scientists, especially at ICVS, for their work in advancing health and knowledge. This Saturday, ICVS marks the day with Family Day—science activities, lab visits, and fun for all ages!

#NationalScientistsDay #ICVSFamilyDay #ICVS

🚀 Excited to launch Germ Connect — our serious game to level up your pathogen knowledge designed with @maudsalmona.bsky.social ! 🧫🧠
From med students to ID & microbiology pros, there's a challenge for everyone.

Play now & test your skills!
#MedEd #SeriousGames

Available 👉 bit.ly/456Rwzi

T-cell branched glycosylation as a mediator of colitis-associated colorectal cancer progression: a potential new risk biomarker in inflammatory bowel disease AbstractBackground and Aims. Inflammatory bowel disease (IBD) is a chronic inflammatory disorder of the gastrointestinal tract, established as a risk facto

academic.oup.com/ecco-jcc/art...

Happy to share our most recent publication on how T cells glycosylation mediates #IBD progression to colorectal cancer defining the risk of colitis-associated cancer.
#glycotime Great work @eduardalgomes.bsky.social @i3suporto.bsky.social @GlycanTrigger

Aspergillus fumigatus biology, immunopathogenicity and drug resistance Nature Reviews Microbiology, Published online: 02 May 2025; doi:10.1038/s41579-025-01180-zIn this Review, van de Veerdonk and colleagues explore Aspergillus fumigatus biology, the host immune responses and the fungal mechanisms of immune evasion, as well as emerging challenges such as virus-associated pulmonary aspergillosis and azole resistance, and reflect on future directions for therapeutics and patient care improvement.

New online! Aspergillus fumigatus biology, immunopathogenicity and drug resistance

📢 ICVS Student Seminar | Monday, 1 PM 📢
Join us for a talk by Ana Raquel Fernandes on “Metabolic circuits of immune regulation and function during fungal infection.”
📍 Auditorium A0.02, School of Medicine, UMinho. Don’t miss it!

🧠✨ ICVS Student Seminars – May 2025
Join us every Monday at 13h (Room A0.02, School of Medicine – UMinho) for student-led talks on immunity, infections, malaria, chronic pain, and cancer.
Support young scientists and discover cutting-edge research!
#ICVSSeminars #UMinho #Research

Will climate change lead to more fungal infections? | News | Wellcome Fungi can keep us healthy or cause disease. As climate change drives fungi to adapt, learn how we can harness the benefits and tackle the threats.

Fungi can protect the environment, grow food and even develop new medicines. 🍄

But they can also cause disease.

As climate change spreads pathogenic fungi to new places, more people worldwide will be at risk.

Learn more in our explainer ⤵️
wellcome.org/news/will-cl...

Monocyte-macrophage membrane expression of IL-1R2 is a severity biomarker in sepsis - Cell Death & Disease Cell Death & Disease - Monocyte-macrophage membrane expression of IL-1R2 is a severity biomarker in sepsis

Happy to have been part of this great team!
Here our latest work published on Cell Death and Disease.

www.nature.com/articles/s41...

Human Immunity to Fungal Infections. New review from Donald Vinh @donvinh.bsky.social @mcgill.ca: rupress.org/jem/article/...

#InfectiousDisease #HostDefense #HumanDiseaseGenetics #Immunodeficiency

🧠🧬✨ We are extremely happy to invite you to join us this April 29th (10h30–12h WEST) for an exciting celebration of the Day of Immunology.

We’re shining a spotlight on brilliant ECRs who are exploring the immune system from every angle:
🧠 |🦠|🔁|🧒|🧫

🔗 Scan the QR code and join us!